Systems and methods for variable filter adjustment by heart rate metric feedback

• US 10,512,403 B2
• Filed: 10/16/2017
• Issued: 12/24/2019
• Est. Priority Date: 08/02/2011
• Status: Active Grant

• Current Assignee: Yukka Magic LLC
• Original Assignee: Valencell, Inc.
• Inventors: Romesburg, Eric Douglas
• Primary Examiner(s): Layno, Carl H
• Assistant Examiner(s): Ghand, Jennifer L
• Application Number:
  US15/784,960
• Publication Number:
  US 20180049645A1
• Time in Patent Office: 799 Days
• CPC Class Codes: A61B 5/0059 using light, e.g. diagnosis by transillumination, diascopy, fluorescence A61B5/0093, A61B5/1455, A61B5/02416 and A61B5/0261 take precedence
• CPC Class Codes: A61B 5/0095 by applying light and detecting acoustic waves, i.e. photoacoustic measurements
• CPC Class Codes: A61B 5/0205 Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
• CPC Class Codes: A61B 5/02416 using photoplethysmograph signals, e.g. generated by infrared radiation A61B5/14552 takes precedence
• CPC Class Codes: A61B 5/0245 by using sensing means generating electric signals, i.e. ECG signals
• CPC Class Codes: A61B 5/0816 Measuring devices for examining respiratory frequency measuring frequency of electric signals G01R23/00
• CPC Class Codes: A61B 5/316 Modalities, i.e. specific diagnostic methods
• CPC Class Codes: A61B 5/318 Heart-related electrical modalities, e.g. electrocardiography [ECG]
• CPC Class Codes: A61B 5/369 Electroencephalography [EEG] devices for psychotechnics A61B5/16
• CPC Class Codes: A61B 5/7225 Details of analog processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation A61B5/30, A61B5/316 take precedence; transformers for specific applications H01F38/00; amplifiers H03F
• CPC Class Codes: A61B 5/725 using specific filters therefor, e.g. Kalman or adaptive filters A61B5/316 take precedence
• CPC Class Codes: A61B 5/7278 Artificial waveform generation or derivation, e.g. synthesising signals from measured signals A61B5/327 takes precedence

Abstract

A physiological signal processing system for a physiological waveform that includes a cardiovascular signal component provides a variable high pass filter that is responsive to the physiological waveform, and that is configured to high pass filter the physiological waveform in response to a corner frequency that is applied. A heart rate metric extractor is responsive to the variable high pass filter and is configured to extract a heart rate metric from the physiological waveform that is high pass filtered. A corner frequency adjuster is responsive to the heart rate metric extractor and is configured to determine the corner frequency that is applied to the variable high pass filter, based on the heart rate metric that was extracted. Analogous methods may also be provided.

Claims

1. A physiological signal processing apparatus, comprising:

a memory comprising a non-transitory computer readable medium having computer program instructions stored therein; and

at least one processor coupled to the memory, wherein the at least one processor is configured to execute the computer program instructions stored in the memory to perform operations comprising;

extracting, via the at least one processor, a heart rate metric for a subject from a cardiovascular signal component of a physiological waveform provided by a physiological sensor that is coupled to the at least one processor; and

resetting the extracting of the at least one processor in response to determining that the physiological waveform is no longer being obtained, wherein the determining that the physiological waveform is no longer being obtained is responsive to detecting a loss of proximity of the physiological sensor to a body of the subject.

2. The physiological signal processing apparatus of claim 1, wherein the resetting the extracting comprises setting the extracted heart rate metric to a predetermined heart rate in response to the determining that the physiological waveform is no longer being obtained.

3. The physiological signal processing apparatus of claim 2, wherein the predetermined heart rate is a resting heart rate.

4. The physiological signal processing apparatus of claim 1, wherein the extracting the heart rate metric is based on an output of a variable filter, and wherein, responsive to detecting a proximity of the physiological sensor to the body of the subject, the operations further comprise determining a corner frequency applied to the variable filter from the heart rate metric.

5. The physiological signal processing apparatus of claim 4, wherein the operations further comprise initially setting a predetermined corner frequency corresponding to a predetermined heart rate prior to the determining the corner frequency that is applied to the variable filter from the heart rate metric.

6. The physiological signal processing apparatus of claim 5, wherein the initially setting the predetermined corner frequency comprises setting the predetermined corner frequency corresponding to the predetermined heart rate until the extracting locks on a heart rate in the physiological waveform.

7. The physiological signal processing apparatus of claim 6, wherein the operations further comprise determining that the extracting locks on the heart rate in the physiological waveform based on a spectral peak of the physiological waveform being within a constant or variable window around the extracted heart rate metric.

8. The physiological signal processing apparatus of claim 4, wherein the resetting the extracting further comprises resetting the corner frequency applied to the variable filter to a predetermined corner frequency corresponding to a predetermined heart rate in response to detecting the loss of proximity of the physiological sensor to the body of the subject.

9. The physiological signal processing apparatus of claim 1, wherein the physiological waveform comprises a photoplethysmograph (PPG) waveform, and wherein the operations further comprise processing the extracted heart rate metric to generate at least one physiological assessment.

10. A physiological signal processing method for a physiological waveform that includes a cardiovascular signal component therein, the physiological signal processing method comprising:

executing, by at least one processor, computer program instructions stored in a non- transitory computer readable medium to perform operations comprising;

extracting a heart rate metric for a subject from the cardiovascular signal component of the physiological waveform, wherein the physiological waveform is provided by a physiological sensor that is coupled to the at least one processor; and

resetting the extracting in response to determining that the physiological waveform is no longer being obtained, wherein the determining that the physiological waveform is no longer being obtained is responsive to detecting a loss of proximity of the physiological sensor to a body of the subject.

11. The physiological signal processing method of claim 10, wherein the resetting the extracting comprises setting the extracted heart rate metric to a predetermined heart rate in response to the determining that the physiological waveform is no longer being obtained.

12. The physiological signal processing method of claim 11, wherein the predetermined heart rate is a resting heart rate.

13. The physiological signal processing method of claim 10, wherein the extracting the heart rate metric is based on an output of a variable filter, and wherein, in response to detecting a proximity of the physiological sensor to the body of the subject, the operations further comprise determining a corner frequency applied to the variable filter from the heart rate metric.

14. The physiological signal processing method of claim 13, wherein the operations further comprise initially setting a predetermined corner frequency corresponding to a predetermined heart rate prior to the determining the corner frequency that is applied to the variable filter from the heart rate metric.

15. The physiological signal processing method of claim 14, wherein the initially setting the predetermined corner frequency comprises setting the predetermined corner frequency corresponding to the predetermined heart rate until the extracting locks on a heart rate in the physiological waveform.

16. The physiological signal processing method of claim 15, wherein the operations further comprise determining that the extracting locks on the heart rate in the physiological waveform based on a spectral peak of the physiological waveform being within a constant or variable window around the extracted heart rate metric.

17. The physiological signal processing method of claim 13, wherein the resetting the extracting further comprises resetting the corner frequency applied to the variable filter to a predetermined corner frequency corresponding to a predetermined heart rate in response to detecting the loss of proximity of the physiological sensor to the body of the subject.

18. The physiological signal processing method of claim 10, wherein the physiological waveform comprises a photoplethysmograph (PPG) waveform, and wherein the operations further comprise processing the extracted heart rate metric to generate at least one physiological assessment.

19. A computer program product for physiological signal processing, the computer program product comprising:

a non-transitory computer readable medium having computer program instructions stored therein that, when executed by at least one processor, causes the at least one processor to perform operations comprising;

extracting a heart rate metric for a subject from a cardiovascular signal component of a physiological waveform provided by a physiological sensor that is coupled to the at least one processor; and

resetting the extracting in response to determining that the physiological waveform is no longer being obtained, wherein the determining that the physiological waveform is no longer being obtained is responsive to detecting a loss of proximity of the physiological sensor to a body of the subject.