Axial lengthening thrombus capture system

• US 10,512,479 B2
• Filed: 12/03/2018
• Issued: 12/24/2019
• Est. Priority Date: 08/06/2015
• Status: Active Grant

• Current Assignee: Vascular Medcure Incorporated (Medtronic Plc)
• Original Assignee: KP Medcure, Inc.
• Inventors: Nguyen, Thanh Van, Nguyen, Duy, Ngo, Tung Hoang
• Primary Examiner(s): Woo, Julian W
• Application Number:
  US16/207,768
• Publication Number:
  US 20190099194A1
• Time in Patent Office: 386 Days
• CPC Class Codes: A61B 17/221 Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions surgical snare instruments A61B17/32056
• CPC Class Codes: A61B 17/320758 with a rotating cutting instrument, e.g. motor driven A61B17/320725, A61B17/32075 and A61B17/320783 take precedence; for removing intra-ocular material A61F9/00763; endoscopic rotatable cutting instruments A61B17/32002
• CPC Class Codes: A61B 2017/00867 shape memory effect
• CPC Class Codes: A61B 2017/00871 polymeric
• CPC Class Codes: A61B 2017/00893 pharmaceutically effective
• CPC Class Codes: A61B 2017/00938 hydrophobic
• CPC Class Codes: A61B 2017/00942 hydrophilic
• CPC Class Codes: A61B 2017/22038 with a guide wire
• CPC Class Codes: A61B 2017/22079 with suction of debris
• CPC Class Codes: A61B 2017/22081 Treatment of vulnerable plaque
• CPC Class Codes: A61B 2017/22084 stone- or thrombus-dissolving
• CPC Class Codes: A61B 2017/2212 having a closed distal end, e.g. a loop
• CPC Class Codes: A61B 2017/2217 single wire changing shape to a gripping configuration
• CPC Class Codes: A61B 2017/320052 Guides for cutting instruments
• CPC Class Codes: A61B 2017/320716 comprising means for preventing embolism by dislodged material
• CPC Class Codes: A61B 2017/320775 Morcellators, impeller or propeller like means
• CPC Class Codes: A61F 2/011 Instruments for their placement or removal
• CPC Class Codes: A61F 2/013 Distal protection devices, i.e. devices placed distally in combination with another endovascular procedure, e.g. angioplasty or stenting
• CPC Class Codes: A61F 2002/016 made from wire-like elements

Abstract

Systems and methods can remove material of interest, including blood clots, from a body region, including but not limited to the circulatory system for the treatment of pulmonary embolism (PE), deep vein thrombosis (DVT), cerebrovascular embolism, and other vascular occlusions.

Claims

1. A clot capture system, comprising:

a shape memory tubular body comprising a first end, a second end, and an axial length therebetween, the first end having an opening,

wherein the shape memory tubular body is transformable to a first expanded configuration in which the first end is expanded but the second end and a majority of the shape memory tubular body is compressed, wherein the shape memory tubular body is folded between the first end and the second end, wherein the shape memory tubular body has a first expanded axial length in the first expanded configuration,

wherein the shape memory tubular body is transformable to a second expanded configuration in which the shape memory tubular body has a second expanded axial length greater than the first expanded axial length, wherein a width of the opening in the first expanded configuration is substantially the same as the width of the opening in the second expanded configuration.

2. The clot capture system of claim 1, wherein the second expanded axial length is at least about 110% of the first axial length.

3. The clot capture system of claim 1, wherein the second expanded axial length is at least about 125% of the first axial length.

4. The capture system of claim 1, wherein the shape memory tubular body is porous.

5. The clot capture system of claim 1, wherein the shape memory tubular body comprises an impermeable, non-porous polymer.

6. The clot capture system of claim 1, wherein the shape memory tubular body comprises a semi-permeable porous polymer.

7. The clot capture system of claim 1, wherein the shape memory tubular body comprises nitinol braided, woven, or non-woven mesh.

8. The clot capture system of claim 1, wherein the shape memory tubular body is uncoated.

9. The clot capture system of claim 1, wherein the shape memory tubular body is coated with a thrombogenic agent.

10. The clot capture system of claim 1, wherein the shape memory tubular body is coated with a hydrophilic or hydrophobic agent.

11. The clot capture system of claim 1, wherein the shape memory tubular body comprises nitinol wire.

12. The clot capture system of claim 1, further comprising a filter collection chamber configured to collect and filter blood obtained from a suction element.

14. The clot capture system of claim 1, further comprising a suction element configured to operably connect with the opening of the shape memory tubular body.

15. The clot capture system of claim 1, further comprising a mechanical thrombectomy element.

16. The clot capture system of claim 15, wherein the mechanical thrombectomy element comprises a macerator.

13. A clot capture system, comprising:

a shape memory tubular body comprising a first end, a second end, and an axial length therebetween, the first end having an opening,

wherein the shape memory tubular body is transformable to a first expanded configuration in which the first end is expanded and the second end is compressed within a delivery instrument, wherein the shape memory tubular body comprises a fold between the first end and the second end, wherein the tubular body has a first expanded axial length in the first expanded configuration,

wherein the shape memory tubular body is configured to invert, evert, or roll out with respect to the delivery instrument to a second expanded configuration in which the shape memory tubular body has a second expanded axial length greater than the first expanded axial length.

17. A clot capture system, comprising:

a shape memory tubular body comprising a first end, a second end, and an axial length therebetween, the first end having an opening,

wherein the shape memory tubular body is transformable to a first expanded configuration in which the first end is expanded but the second end is compressed, wherein the shape memory tubular body comprises a fold between the first end and the second end, wherein the tubular body has a first expanded axial length in the first expanded configuration,

wherein the shape memory tubular body is transformable to a second expanded configuration in which the shape memory tubular body has a second expanded axial length greater than the first expanded axial length, and

an expanding guide element configured to receive the shape memory tubular body.

18. The clot capture system of claim 17, wherein the expanding guide element comprises an open funnel distal tip.

19. The clot capture system of claim 18, wherein the open funnel distal tip is porous to allow flow.