Medicament delivery device having an activating mechanism

• US 10,518,032 B2
• Filed: 05/11/2015
• Issued: 12/31/2019
• Est. Priority Date: 05/12/2014
• Status: Active Grant

• Current Assignee: Sanofi
• Original Assignee: Sanofi
• Inventors: Helmer, Michael
• Primary Examiner(s): Bosworth, Kami A
• Assistant Examiner(s): Lalonde, Alexandra
• Application Number:
  US15/309,717
• Publication Number:
  US 20170136183A1
• Time in Patent Office: 1,695 Days
• CPC Class Codes: A61M 2005/2013 triggering of discharging means by contact of injector with patient body
• CPC Class Codes: A61M 2005/2026 Semi-automatic, e.g. user activated piston is assisted by additional source of energy
• CPC Class Codes: A61M 2005/247 with fixed or steady piercing means, e.g. piercing under movement of ampoule
• CPC Class Codes: A61M 5/2033 Spring-loaded one-shot injectors with or without automatic needle insertion multishot dosing syringes A61M5/31525, needle insertion only A61M5/3287
• CPC Class Codes: A61M 5/2466 by piercing without internal pressure increase A61M5/2429 takes precedence
• CPC Class Codes: A61M 5/3202 Devices for protection of the needle before use, e.g. caps A61M5/50 takes precedence; for infusion spikes A61M5/1626; protectors for sharps A61B50/3001
• CPC Class Codes: A61M 5/347 rotatable, e.g. bayonet or screw A61M5/344 takes precedence

Abstract

The disclosure relates to medicament delivery device including an activating mechanism, wherein the activating mechanism includes a hollow injection needle, a cartridge containing a dosage of a medicament, a cartridge carrier including at least one resilient arm for holding the cartridge, a removable needle cap for covering the injection needle, and a drive element adapted to couple with the cartridge, wherein the cartridge is retained in a position spaced apart from the injection needle in a proximal direction (P) by the at least one resilient arm when the medicament delivery device is in an initial position (P1), and wherein by removing the needle cap, the cartridge is releasable to be pushed into a distal direction (D) by the drive element with respect to the cartridge carrier.

Claims

1. A medicament delivery device comprising an activating mechanism, the activating mechanism comprising:

a hollow injection needle;

a cartridge containing a dosage of a medicament;

a cartridge carrier comprising at least one resilient arm configured to hold the cartridge;

a removable needle cap configured to cover the injection needle; and

a drive element adapted to couple with the cartridge;

wherein the cartridge is retained in a position spaced apart from the injection needle in a proximal direction by the at least one resilient arm when the medicament delivery device is in an initial position,

wherein by removing the needle cap, the cartridge is releasable and configured to be pushed into a distal direction by the drive element with respect to the cartridge carrier,

wherein an inner surface of a proximal end of the removable needle cap is configured to bear against an outer surface of the at least one resilient arm, and

wherein an outer surface of the proximal end of the removable needle cap is configured to bear against an inner surface of the cartridge carrier.

2. The medicament delivery device according to claim 1, wherein the at least one resilient arm is configured to be deformed radially outwards when the cartridge is pushed in the distal direction.

3. The medicament delivery device according to claim 1, wherein the drive element is a spring element that is arranged between a proximal end of the cartridge and a proximal end of the cartridge carrier, and

wherein the spring element is configured to be prestressed in the proximal direction when the medicament delivery device is in the initial position and destressed in the distal direction when the needle cap is removed.

4. The medicament delivery device according to claim 3, wherein the injection needle is adapted to pierce a sealing element of the cartridge when the cartridge is pushed in the distal direction.

5. The medicament delivery device according to claim 3, wherein the spring element is coupled to the cartridge carrier by a bayonet socket.

6. The medicament delivery device according to claim 1, further comprising a sleeve that is arranged within an outer body and movable with respect to the outer body so as to cover or to expose the injection needle.

7. The medicament delivery device according to claim 6, wherein

the injection needle is covered by the sleeve when the medicament delivery device is in the initial position, and

wherein the injection needle is exposed when the sleeve moves in the proximal direction with respect to the outer body.

8. The medicament delivery device according to claim 1, further comprising

a bung disposed within a proximal end of the cartridge to seal the proximal end of the cartridge when the medicament delivery device is in the initial position,

wherein the piston rod that is adapted to engage and displace the bung within the cartridge.

9. The medicament delivery device according to claim 1, wherein the at least one resilient arm is a lug-shaped cut out comprising

a first section protruding radially inwards from a circumference of the cartridge carrier;

and

a hook-shaped second section protruding axially in the distal direction,

wherein a hook end of the hook-shaped second section protrudes radially inwards.

10. The medicament delivery device according to claim 9, wherein the drive element is in the form of a spring element arranged between a proximal end of the cartridge and a proximal end of the cartridge carrier, and a shoulder of the cartridge is configured to bear against the hook end of the hook-shaped second section when the spring element is prestressed in the proximal direction, and

wherein the spring element is configured to be prestressed in the proximal direction when the medicament delivery device is in the initial position and destressed in the distal direction when the needle cap is removed.

11. The medicament delivery device according to claim 1, wherein a transverse opening is arranged through the cartridge carrier, wherein a sealing part is arrangeable within the transverse opening distally from the cartridge and proximally from an inner needle section.

12. The medicament delivery device according to claim 11, wherein the transverse opening is further arranged through the needle cap.

13. The medicament delivery device according to claim 11, further comprising a sleeve that is arranged within an outer body and movable with respect to the outer body so as to cover or expose the injection needle, wherein the transverse opening is further arranged through the outer body.

14. The medicament delivery device according to claim 11, further comprising a sleeve that is arranged within an outer body and movable with respect to the outer body so as to cover or expose the injection needle, wherein the transverse opening is further arranged through the sleeve.

15. The medicament delivery device according to claim 14, wherein the needle cap and the sealing part are integrally shaped with the flexible strip.

16. The medicament delivery device according to claim 11, wherein the sealing part is connected by a flexible strip to the needle cap.

17. The medicament delivery device of claim 1, wherein the medicament comprises a pharmaceutically active compound.