Automated reservoir fill system

• US 10,532,835 B2
• Filed: 06/24/2014
• Issued: 01/14/2020
• Est. Priority Date: 05/10/2011
• Status: Active Grant

• Current Assignee: Medtronic Minimed Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Minimed Incorporated (Medtronic Plc)
• Inventors: Chong, Colin A., Ibranyan, Arsen, Lorenzen, Eric M., Halili, Edgardo C.
• Primary Examiner(s): Price, Nathan R
• Assistant Examiner(s): Lee, Weng
• Application Number:
  US14/313,248
• Publication Number:
  US 20140305544A1
• Time in Patent Office: 2,030 Days
• CPC Class Codes: A61J 1/20 Arrangements for transferring or mixing fluids, e.g. from vial to syringe
• CPC Class Codes: A61J 1/2003 Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
• CPC Class Codes: A61J 1/2096 Combination of a vial and a syringe for transferring or mixing their contents
• CPC Class Codes: A61M 2205/3368 Temperature
• CPC Class Codes: A61M 2209/045 for filling, e.g. for filling reservoirs
• CPC Class Codes: A61M 5/00 Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests vaccination appliances for veterinary use A61D1/025 ; tube connectors, tube couplings, valves or branch units specially adapted for medical use A61M39/00; containers specially adapted for medical or pharmaceutical purposes A61J1/00; combinations of vial and syringe for mixing or transferring their contents A61J1/20; holders for containers for collecting, storing or administering blood or medical fluids A61J1/16
• CPC Class Codes: A61M 5/14244 adapted to be carried by the patient, e.g. portable on the body
• CPC Class Codes: A61M 5/36 with means for eliminating or preventing injection or infusion of air into body dialysis systems, blood oxygenators A61M1/14; haemofiltration equipment A61M1/34; automatic tube cut-off A61M39/281
• CPC Class Codes: B65B 3/003 Filling medical containers such as ampoules, vials, syringes or the like

Abstract

An automated reservoir filling system for a portable medical device is disclosed. The system includes a vial sealed by a septum partially filled with a liquid and a gas occupying a headspace. The system further includes a reservoir with a volume defined between a reservoir septum and a plunger head. The plunger head is coupled to a plunger arm which is further coupled to a drive system. Further included is a transfer system with a vial end that pierces the vial septum and remains in contact with the liquid, and a reservoir end that pierces the reservoir septum and remains in the reservoir volume. A controller coupled to the drive system to actuates the drive system automatically drawing fluid from the vial to the reservoir through the degas system.

Claims

1. A system to automatically fill a reservoir for a portable medical device comprising:

a vial having an exterior surface and an interior vial volume partially filled with a liquid at a temperature and a gas, the gas occupying a headspace, the vial further having a vial port sealed with a vial septum;

a reservoir having a reservoir volume defined between a reservoir port and a plunger head, the plunger head coupled to a plunger arm, the plunger arm coupled to a drive system defined to move the plunger arm within a chamber, the reservoir port being sealed by a reservoir septum;

a transfer system having a vial end defined to pierce the vial septum and remain in contact with the liquid, the transfer system further having a reservoir end defined to pierce the reservoir septum and remain in the reservoir volume, the transfer system adapted to enable continuous fluid flow between the vial and the reservoir during filling of the reservoir and adapted to be removable from the reservoir after filling of the reservoir;

a degas system defined to draw a vacuum on the headspace within the vial via the drive system;

an agitator coupled to the exterior of the vial and not in contact with the interior vial volume of the vial, the agitator defined to introduce pulses from the exterior of the vial to assist in degassing the liquid in the vial; and

a controller coupled to the drive system, the controller defined to actuate the agitator while air in the headspace is drawn through the transfer system to draw a partial vacuum on the headspace through the degas system and to degas the liquid in the vial, the controller further defined to actuate the drive system to draw the degassed liquid from the vial through the transfer system into the reservoir.

2. A system as defined in claim 1, wherein the transfer system further includes a check valve coupled to the controller and a vacuum coupled to the check valve, wherein the controller is defined to actuate the vacuum for a specified period of time so the partial vacuum is drawn on the headspace for a specified period of time.

3. A system as defined in claim 2, wherein after the specified period of time has lapsed, the controller is defined to actuate the check valve and the drive system to draw the degassed liquid from the vial into the reservoir.

4. A system as defined in claim 1, wherein the transfer system further includes a check valve coupled with the controller, and wherein the controller actuates the check valve and the drive system to maintain the partial vacuum drawn on the headspace in the vial and to expel a gas from the reservoir.

5. A system as defined in claim 4, wherein the controller actuates the check valve and the drive system to draw the degassed liquid from the vial into the reservoir.