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Compositions and methods for modulating Ataxin 3 expression

  • US 10,533,175 B2
  • Filed: 09/23/2016
  • Issued: 01/14/2020
  • Est. Priority Date: 09/25/2015
  • Status: Active Grant
First Claim
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1. An oligomeric compound comprising a modified oligonucleotide consisting of 15-25 linked nucleosides, wherein the oligonucleotide has a nucleobase sequence comprising at least 15, 16, 17, or 18 contiguous nucleobases of any one of SEQ ID NO:

  • 9 or 10, wherein at least one nucleoside of the modified oligonucleotide comprises a modified sugar.

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