Medical device for modification of left atrial appendage and related systems and methods

• US 10,537,332 B2
• Filed: 04/19/2017
• Issued: 01/21/2020
• Est. Priority Date: 06/17/2009
• Status: Active Grant

• Current Assignee: Coherex Medical, Inc. (Johnson & Johnson)
• Original Assignee: Coherex Medical, Inc. (Johnson & Johnson)
• Inventors: Edmiston, Daryl R., Davis, Clark C., Martin, John Alexander, Miles, Scott D.
• Primary Examiner(s): Louis, Richard G
• Application Number:
  US15/491,347
• Publication Number:
  US 20170215889A1
• Time in Patent Office: 1,007 Days
• CPC Class Codes: A61B 17/0057 Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect sutures A61B17/04; closing rectum or urethra near body surface A61F2/0009
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12122 within the heart for closing a cardiac septal defect A61B17/0057
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/12177 comprising additional materials, e.g. thrombogenic, having filaments, having fibers or being coated
• CPC Class Codes: A61B 2017/00575 for closure at remote site, e.g. closing atrial septum defects
• CPC Class Codes: A61B 2017/00597 Implements comprising a membrane
• CPC Class Codes: A61B 2017/0069 with universal joint, cardan joint
• CPC Class Codes: A61B 2017/1205 Introduction devices
• CPC Class Codes: A61B 2017/12054 Details concerning the detachment of the occluding device from the introduction device
• CPC Class Codes: A61B 2017/12095 Threaded connection
• CPC Class Codes: A61F 2/011 Instruments for their placement or removal
• CPC Class Codes: A61F 2/2427 Devices for manipulating or deploying heart valves during implantation
• CPC Class Codes: A61F 2002/016 made from wire-like elements

Abstract

Devices, methods and systems are provided for occluding an opening within the tissue of a body, such as a left atrial appendage. In one embodiment, a medical device coupled to a delivery catheter includes a fluid flow path that facilitates contrast fluid to pass through the delivery catheter and the medical device to a distal side thereof to provide imaging information as to the position of the medical device positioned in the opening, such as the left atrial appendage. In another embodiment, a medical device is coupled to a delivery catheter, the medical device including flaps adjacent a hub of the medical device that close-off a bore of the hub upon the catheter being detached from the medical device.

Claims

1. A method for modifying a left atrial appendage (“

LAA”

) of a heart, the method comprising;

anchoring a medical device in the LAA with a delivery catheter directly coupled to a hub of the medical device such that the medical device includes an occluder material extending over a proximal side of medical device with occluder material flaps adjacent the hub in an open first position, the medical device having a spring element positioned over the hub and enveloped at least partially by the occluder material flaps; and

detaching the catheter from the hub of the medical device such that the occluder material flaps adjacent the hub automatically move to a closed second position to close-off the hub of the medical device.

2. The method according to claim 1, wherein the anchoring comprises anchoring the medical device with the occluder material being a polymeric material.

3. The method according to claim 1, wherein the detaching comprises unthreading the catheter from the medical device.

4. The method according to claim 1, wherein the detaching comprises detaching the catheter having threads from a threaded portion of the medical device.

5. The method according to claim 1, wherein the detaching comprises closing a bore of the hub with the occluder material flaps being biased to the closed position such that the occluder material flaps substantially eliminate exposure of metallic material on the proximal side of the medical device at the hub of the medical device.

6. A method for modifying a left atrial appendage (“

LAA”

) of a heart, the method comprising;

anchoring a medical device in the LAA with a delivery catheter coupled to a hub of the medical device such that the medical device includes a moveable portion positioned adjacent the hub and moveable between an open first position and a closed second position, the moveable portion in the open first position with the delivery catheter coupled to the medical device, the moveable portion having a spring element adjacent the hub and biased toward a flat configuration; and

detaching the delivery catheter from the hub of the medical device such that the moveable portion adjacent the hub automatically moves to the closed second position to close-off the hub of the medical device.

7. The method according to claim 6, wherein the anchoring comprises anchoring the medical device including the moveable portion having the spring element, the spring element biased upon being in the open first position and the spring element relaxed upon being in the closed second position.

8. The method according to claim 6, wherein the anchoring comprises anchoring the medical device with a polymeric material positioned at least partially over a proximal side of the medical device.

9. The method according to claim 6, wherein the detaching comprises unthreading the delivery catheter from the medical device.

10. The method according to claim 6, wherein the detaching comprises detaching the delivery catheter having threads from a threaded portion of the medical device.

11. The method according to claim 6, wherein the detaching comprises closing a bore of the hub with the moveable portion being biased to the closed position such that the moveable portion substantially eliminates exposure of metallic material on the proximal side of the medical device at the hub of the medical device.

12. The method according to claim 6, wherein the anchoring comprises anchoring the medical device with the moveable portion defining material flaps sized to at least partially envelope the spring element.

13. A method for closing-off an opening, the method comprising:

anchoring a medical device in the opening with a delivery catheter coupled to a hub of the medical device such that the medical device includes a moveable portion positioned adjacent the hub, the moveable portion being moveable between an open first position and a closed second position, the moveable portion being in the open first position with the delivery catheter coupled to the medical device, the moveable portion having a spring element positioned adjacent the hub and biased toward the closed position; and

detaching the delivery catheter from the hub of the medical device such that the spring element adjacent the hub automatically moves the moveable portion to the closed second position to cover a proximal side of the hub of the medical device.

14. The method according to claim 13, wherein the anchoring comprises anchoring the medical device with the moveable portion defining material flaps sized to at least partially envelope the spring element.

15. The method according to claim 14, wherein the anchoring comprises anchoring the medical device such that the material flaps are spaced apart in the open first position and, upon detaching the delivery catheter from the hub, the material flaps move to an overlapping configuration in the closed second position.

16. The method according to claim 13, wherein the anchoring comprises anchoring the medical device with the moveable portion including a polymeric material.

17. The method according to claim 13, wherein the anchoring comprises anchoring the medical device with the moveable portion defining material flaps sized to at least partially envelope the spring element.

18. The method according to claim 13, wherein the detaching comprises unthreading the delivery catheter from the medical device.

19. The method according to claim 13, wherein the detaching comprises detaching the delivery catheter having threads from a threaded portion of the medical device.

20. The method according to claim 13, wherein the detaching comprises closing a bore of the hub with the moveable portion being biased to the closed position such that the moveable portion defines flaps that cover metallic material on the proximal side of the medical device at the hub of the medical device.