System and method for choosing electrodes in an implanted stimulator device

• US 10,537,741 B2
• Filed: 12/05/2005
• Issued: 01/21/2020
• Est. Priority Date: 12/03/2004
• Status: Active Grant

• Current Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Inventors: Bradley, Kerry, Manola, Ljubomir, Holsheimer, Jan
• Primary Examiner(s): Abreu, Michael J D
• Application Number:
  US11/295,168
• Publication Number:
  US 20060195159A1
• Time in Patent Office: 5,160 Days
• Field of Search: 607 9, 607 17, 607 46, 607 48, 607 59, 607 62
• CPC Class Codes: A61N 1/36132 using patient feedback
• CPC Class Codes: A61N 1/3614 based on impedance measurement
• CPC Class Codes: A61N 1/36185 Selection of the electrode configuration

Abstract

A method of selecting a subset of electrodes in a stimulator device implanted in a patient for further clinical evaluation is disclosed. The method comprises measuring at least first and second measurement for each of the plurality of electrodes that are indicative of the ability of the electrode if activated to provide useful therapy to the patient in which the stimulator device is implanted A weight is then determined for each of the measurements. The weight is then applied to each electrode measurement, which measurement may be normalized, and the weighted measurements for each electrode are preferably summed to arrive at a value which itself is indicative of a particular electrode'"'"'s ability to provide useful therapy to the patient. These values can then be used to determine a subset of the electrodes useful for further clinical evaluation in the patient, which improved the accuracy and speeding determining appropriate patient therapy.

Claims

1. A method of using a plurality of electrodes of a stimulator device implanted in a patient, the method comprising:

providing a stimulator device comprising a plurality of electrodes, wherein the stimulator device is implanted in a patient;

taking a first type of measurement for each of the plurality of electrodes of the stimulator device;

taking a second different type of measurement for each of the plurality of electrodes of the stimulator device, wherein the measurements are indicative of the ability of the respective electrode if activated to provide useful therapy to the patient in which the stimulator device is implanted;

applying a first weight to the first type of measurement to respectively arrive at first weighted measurements for the respective electrodes;

applying a second weight to the second type of measurement to respectively arrive at second weighted measurements for the respective electrodes;

computing a function of the first and second weighted measurements to arrive at a value;

using the value to determine a subset of the electrodes; and

activating at least one electrode of the subset of the electrodes to deliver therapy to the patient.

2. The method of claim 1, wherein at least one of the first and second types of measurement is selected from the group consisting of electrode impedance, field potential, and nerve response.

3. The method of claim 2, wherein one of the first and second types of measurement is a quantitative value indicative of subjective user feedback based on stimulation of a given electrode.

4. The method of claim 1, wherein the first type of measurement is one of an electrode impedance, a field potential, a nerve response, and a qualitative value indicative of subjective user feedback based on stimulation of a given electrode, and the second type of measurement is another different one of the electrode impedance, the field potential, the nerve response, and the qualitative value indicative of subjective user feedback based on stimulation of a given electrode.

5. The method of claim 1, wherein the first type of measurement is objective and the second type of measurement is subjective.

6. The method of claim 1, wherein the function comprises summing the first and second weighted measurements for each electrode.

7. The method of claim 1, wherein one of the first and second types of measurement is indicative of a thickness of a cerebro-spinal fluid.

8. The method of claim 1, wherein at least one of the first and second types of measurement is normalized before applying at least one of the first and second weights to the at least one first and second types of measurement.

9. The method of claim 1, further comprising determining at least one of the first and second weights for at least one of the respective first and second types of measurement by an assessment of a variance of the respective measurements between the plurality of electrodes.

10. The method of claim 1, wherein at least one of the first and second weights is predetermined.

11. The method of claim 1, wherein the first type of measurement is considered more significant and the first weight is applied to the first type of measurement, such that the first type of measurement is given a larger influence on the value.

12. A method of using a plurality of electrodes of a stimulator device implanted in a patient, the method comprising:

providing a stimulator device comprising a plurality of electrodes, wherein the stimulator device is implanted in a patient;

taking a first type of measurement for each of the plurality of electrodes of the stimulator device;

taking a second different type of measurement for each of the plurality of electrodes of the stimulator device;

applying a first weight to the first type of measurement to arrive at first weighted measurements for the respective electrodes;

applying a second weight to the second type of measurement to arrive at second weighted measurements for the respective electrodes;

processing the first and second weighted measurements for each electrode to arrive at a value for each electrode;

using the values to determine a subset of the electrodes; and

activating at least one electrode of the subset of the electrodes to deliver therapy to the patient.

13. The method of claim 12, wherein at least one of the first and second types of measurement is selected from the group consisting of electrode impedance, field potential, and nerve response.

14. The method of claim 13, wherein one of the first and second types of measurement is a quantitative value indicative of subjective user feedback based on stimulation of a given electrode.

15. The method of claim 12, wherein applying the first and second weights to the first and second types of measurement to arrive at the first and second weighted measurements for the respective electrodes comprises multiplying the weight for each measurement by the measurement for each electrode.

16. The method of claim 12, wherein one of the first and second types of measurement is indicative of a thickness of a cerebro-spinal fluid.

17. The method of claim 12, wherein at least one of the first and second types of measurement is normalized before applying at least one of the first and second weights to the at least one first and second types of measurement.

18. The method of claim 12, further comprising determining at least one of the first and second weights for at least one of the respective first and second types of measurement by an assessment of the variance of the respective measurements between the plurality of electrodes.

19. The method of claim 12, wherein at least one of the first and second weights is predetermined.

20. The method of claim 12, wherein processing the weighted measurements for each electrode comprises summing the first and second weighted measurements for each electrode.

21. The method of claim 12, wherein the first measurement type is objective and the second types of measurement is subjective.

22. The method of claim 12, wherein the first type of measurement is considered more significant and the first weight is applied to the first type of measurement, such that the first type of measurement is given a larger influence on the value.