Opto-acoustic imaging system with detection of relative orientation of light source and acoustic receiver using acoustic waves
First Claim
1. A method for determining position and orientation of an optical delivery unit relative to an acoustic receiving unit, the method comprising:
- sampling and recording acoustic signals from a volume of a subject, the acoustic signals collected by the acoustic receiving unit;
identifying an acoustic response of a first fiducial marker and an acoustic response of a second fiducial marker based on the acoustic signals, wherein the acoustic responses indicate time separations between times of emission of the acoustic signals from a corresponding one of first and second fiducial marker sites and times of reception of the acoustic signals by the acoustic receiving unit at a data collection position relative to a coordinate reference frame; and
,determining position and orientation of the optical delivery unit in the coordinate reference frame based on the acoustic response of the first fiducial marker and the acoustic response of the second fiducial marker.
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Accused Products
Abstract
In an embodiment, a system and method are provided for determining position and orientation of an optical delivery unit relative to an acoustic receiving unit, in the field of opto-acoustic imaging, wherein the optical delivery unit comprises a first fiducial marker site configured to emit acoustic responses and a second fiducial marker site configured to emit acoustic responses. A plurality of acoustic signals from a volume of a subject are sampled and recorded, each of the plurality of acoustic signals being collected at a different data collection position relative to a coordinate reference frame. The system is configured to identify in each of the plurality of acoustic signals a response of a first fiducial marker and a response of a second fiducial marker. Each identified response indicates a separation between a fiducial marker site and a data collection position of an acoustic signal. The system determines the position and orientation of the optical delivery unit in the coordinate reference frame by using the identified responses of the first fiducial marker and the identified responses of the second fiducial marker.
68 Citations
25 Claims
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1. A method for determining position and orientation of an optical delivery unit relative to an acoustic receiving unit, the method comprising:
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sampling and recording acoustic signals from a volume of a subject, the acoustic signals collected by the acoustic receiving unit; identifying an acoustic response of a first fiducial marker and an acoustic response of a second fiducial marker based on the acoustic signals, wherein the acoustic responses indicate time separations between times of emission of the acoustic signals from a corresponding one of first and second fiducial marker sites and times of reception of the acoustic signals by the acoustic receiving unit at a data collection position relative to a coordinate reference frame; and
,determining position and orientation of the optical delivery unit in the coordinate reference frame based on the acoustic response of the first fiducial marker and the acoustic response of the second fiducial marker. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A system comprising:
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an optical energy delivery unit comprising an optical energy exit port adapted to deliver optical energy to a volume of a subject; an acoustic receiving unit configured to receive acoustic signals from the volume; first and second fiducial marker sites configured to emit acoustic response to be received by the acoustic receiving unit; a processing unit configured to perform processing of the acoustic signals received by the acoustic receiving unit, including determining a relative position of the optical energy delivery unit respective to the acoustic receiving unit; wherein determining the relative position of the optical energy delivery unit respective to the acoustic receiving unit includes determining a time separation between a first time corresponding to emission of an acoustic signal of the acoustic signals from a corresponding one of the first and second fiducial marker sites and a second time when at least a portion of the acoustic signal is received at the acoustic receiving unit; and
,display unit adapted to display an opto-acoustic image representing the volume. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19)
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20. A system, comprising:
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an acoustic receiver located on a distal surface of a primary contact unit, the primary contact unit comprising a distal end including its distal surface, the distal end of the primary contact unit being adapted to acoustically couple with a surface of a volume of tissue, the primary contact unit further comprising a proximal end; a first optically absorbing fiducial located on a distal surface of a secondary contact unit, the secondary contact unit comprising a distal end including its distal surface, which distal end of the secondary contact unit is adapted to acoustically couple with the volume; and
,a processing subsystem configured to perform processing comprising; identifying acoustic responses of the first optically absorbing fiducial and of the second optically absorbing fiducial by analyzing acoustic signals received by the acoustic receiver; and
,determining the position of the secondary contact unit respective to the primary contact unit using the identified responses; wherein the acoustic responses are based on time separations between an acoustic wave emitted at a fiducial marker site and receiving the acoustic wave emitted at a data collection position. - View Dependent Claims (21, 22, 23, 24, 25)
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Specification