Diagnostic simulator

• US 10,542,892 B2
• Filed: 07/27/2017
• Issued: 01/28/2020
• Est. Priority Date: 11/02/2011
• Status: Active Grant

• Current Assignee: Seno Medical Instruments, Inc.
• Original Assignee: Seno Medical Instruments, Inc.
• Inventors: Herzog, Donald G., Ackerman, William
• Primary Examiner(s): Hoffa, Angela M
• Assistant Examiner(s): Bor, Helene
• Application Number:
  US15/661,090
• Publication Number:
  US 20170332915A1
• Time in Patent Office: 915 Days
• CPC Class Codes: A61B 5/0095 by applying light and detecting acoustic waves, i.e. photoacoustic measurements
• CPC Class Codes: A61B 5/14542 for measuring blood gases A61B5/14551 takes precedence
• CPC Class Codes: A61B 8/4281 characterised by sound-transmitting media or devices for coupling the transducer to the tissue
• CPC Class Codes: G01N 29/0654 Imaging
• CPC Class Codes: G01N 29/2418 using optoacoustic interaction with the material, e.g. laser radiation, photoacoustics photoacoustic cells G01N21/1702; measuring characteristics of vibrations by using radiation-sensitive means G01H9/00; acousto-optical conversion techniques for short-range imaging G01S15/8965; sound-producing devices using laser bundle G10K15/046
• CPC Class Codes: G01N 29/30 Arrangements for calibrating or comparing, e.g. with standard objects

Abstract

A testing apparatus for an optoacoustic device includes a light pulse sensor operatively connected to a light output port of the optoacoustic device, the light pulse sensor being adapted to sense a pulse of light capable of generating an optoacoustic response in a subject and to distinguish between the light pulse and the at least one other light pulse on the basis of the predominant wavelength. The light pulse sensor outputs a trigger signal associated with the distinguished light pulse when such light pulse is sensed. A transducer signal simulator outputs a first plurality of electrical signals simulating those produced by a transducer array and reflective of an optoacoustic response in a subject to a light pulse at a first wavelength in response to a trigger signal from the light pulse sensor associated with a light pulse having a first wavelength. The simulator outputs a second plurality of electrical signals simulating those produced by a transducer array and reflective of an optoacoustic response in a subject to a light pulse at a second predominant wavelength in response to a trigger signal from the light pulse sensor associated with a light pulse having a second wavelength. Conductors carry the plurality of electrical signals output by the transducer signal simulator to the pins of a multi-pin connector.

Claims

1. A testing apparatus for testing operation of an optoacoustic device comprising:

a light pulse sensor configured to receive light pulses transmitted from a light output port of an optoacoustic device and further configured;

i) to detect a first light pulse having a first predominant wavelength and a second light pulse having a second predominant wavelength, and ii) to output a trigger signal in response to detection of at least one of the first and second light pulses; and

a signal output unit configured to;

receive the trigger signal from the light pulse sensor;

output a first simulated electrical response signals simulating an optoacoustic response of the subject tissue to the first light pulse; and

output a second simulated electrical response signals simulating an optoacoustic response of the subject tissue to the second light pulse.

2. The testing apparatus as set forth in claim 1, further comprising a plurality of conductors configured for carrying the first and second plurality of simulated electrical response signals output by the signal output unit to the optoacoustic device.

3. The testing apparatus as set forth in claim 1, wherein the signal output unit is configured to store a plurality of stored signal sets, the plurality of stored signal sets including a first stored signal set corresponding to the first plurality of simulated electrical response signals and a second stored signal set corresponding to the second plurality of simulated electrical response signals.

4. The testing apparatus as set forth in claim 3, wherein the signal output unit comprises a selector configured to select at least one of the first stored signal set and the second stored signal set.

5. The testing apparatus as set forth in claim 4, wherein the testing apparatus further comprises a user interface wherein the selector is implemented in software with the user interface.

6. The testing apparatus as set forth in claim 3, wherein the first stored signal set comprises data associated with a first actual optoacoustic response of a subject tissue recorded by the transducer array during a first previous operation of the optoacoustic device.

7. The testing apparatus as set forth in claim 6, wherein the second stored signal set comprises data associated with a second actual optoacoustic response of a subject tissue recorded by the transducer array during a second previous operation of the optoacoustic device.

8. The testing apparatus as set forth in claim 3, wherein the plurality of stored signal sets further includes a diagnostic stored signal set comprising data associated with a plurality of simulated electrical response signals that could not reasonably correspond to an optoacoustic response of a subject tissue recorded by the transducer array.

9. The testing apparatus as set forth in claim 1, wherein the light pulse sensor comprises:

a first light sensor configured to sense a pulse of light having the first predominant wavelength and configured to output a first signal; and

a second light sensor configured to sense a pulse of light having the second predominant wavelength and configured to output a second signal,

wherein the trigger signal output by the light pulse sensor is a combination of the first and second signals.

10. The testing apparatus as set forth in claim 1, wherein the signal output unit is configured to receive sinogram data from the optoacoustic device and create signal set pairs based on the sinogram data received.

11. A method of testing operation of an optoacoustic device comprising:

receiving in a light pulse sensor, light pulses transmitted from light output port of an optoacoustic device;

detecting in the light pulses received a first light pulse having a first predominant wavelength or a second light pulse having a second predominant wavelength;

outputting a trigger signal responsive to detecting the at least one of the first and second light pulses;

receiving in a signal output unit the trigger signal from the light pulse sensor;

simulating an optoacoustic response of the subject tissue to the first light pulse responsive to detecting the first light pulse; and

simulating an optoacoustic response of the subject tissue to the second light pulse responsive to detecting the second light pulse.

12. The method as set forth in claim 11, further comprising storing signal sets, the signal sets including a first signal set corresponding to the first plurality of simulated electrical response signals and a second signal set corresponding to the second plurality of simulated electrical response signals.

13. The method as set forth in claim 12, wherein the first signal set comprises data associated with a first actual optoacoustic response of a subject tissue recorded by a transducer array.

14. The method as set forth in claim 13, wherein the second signal set comprises data associated with a second actual optoacoustic response of a subject tissue recorded by transducer array.

15. The method as set forth in claim 12, wherein the signal sets further include a diagnostic signal set comprising data associated with a plurality of simulated electrical response signals that could not reasonably correspond to an optoacoustic response of a subject tissue recorded by the transducer array.

16. The method as set forth in claim 11, wherein the light pulse sensor comprises a first light sensor and a second light sensor and wherein:

detecting in the received light pulses comprises;

sensing in the first light sensor a pulse of light having the first predominant wavelength and outputting a first signal; and

sensing in the second light sensor a pulse of light having the second predominant wavelength and outputting a second signal; and

outputting the trigger signal comprises combining the first and second signals to generate the trigger signal.

17. The method as set forth in claim 11, further comprising:

receiving sinogram data from an optoacoustic system;

creating signal set pairs based on the sinogram data received;

verifying the trigger signal based on at least one signal set pair created based on the sinogram data received.