Adaptive radiotherapy treatment using ultrasound
First Claim
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1. A method of monitoring a target tissue in a patient during a radiation treatment, comprising:
- positioning an ultrasound imaging device such that the ultrasound imaging device is in contact with the patient'"'"'s perineum;
using the ultrasound imaging device to scan, transperineally, a target tissue in a genitourinary region of the patient to obtain, prior to a radiation fraction, a baseline image of the target tissue and surrounding tissue;
delivering the radiation fraction along at least one beam-delivery path to the target tissue using a radiation therapy device, wherein the at least one beam-delivery path is directed to the patient'"'"'s anatomy in a non-transperineal direction;
simultaneously delivering the radiation fraction while obtaining a plurality of ultrasound images using the ultrasound imaging device, wherein the ultrasound imaging device is positioned to obtain, from at least one transperineal direction, the plurality of ultrasound images, such that the ultrasound imaging device does not intersect the at least one beam-delivery path while obtaining the plurality of ultrasound images;
comparing the one or more of the plurality of ultrasound images with the baseline image; and
determining intrafractional movement of at least one of the target tissue or the surrounding tissue based on the compared one or more ultrasound images as the radiation fraction is delivered to the patient by the radiation therapy device.
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Abstract
Radiation treatment is delivered to a patient by positioning the patient such that a radiation beam is delivered to a lesion within the patient along a beam-delivery path while securing a diagnostic imaging device about the patient such that the diagnostic imaging device does not intersect the beam-delivery path. Radiation therapy is simultaneously delivered along the beam-delivery path while diagnostic images are obtained using the imaging device.
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Citations
16 Claims
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1. A method of monitoring a target tissue in a patient during a radiation treatment, comprising:
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positioning an ultrasound imaging device such that the ultrasound imaging device is in contact with the patient'"'"'s perineum; using the ultrasound imaging device to scan, transperineally, a target tissue in a genitourinary region of the patient to obtain, prior to a radiation fraction, a baseline image of the target tissue and surrounding tissue; delivering the radiation fraction along at least one beam-delivery path to the target tissue using a radiation therapy device, wherein the at least one beam-delivery path is directed to the patient'"'"'s anatomy in a non-transperineal direction; simultaneously delivering the radiation fraction while obtaining a plurality of ultrasound images using the ultrasound imaging device, wherein the ultrasound imaging device is positioned to obtain, from at least one transperineal direction, the plurality of ultrasound images, such that the ultrasound imaging device does not intersect the at least one beam-delivery path while obtaining the plurality of ultrasound images; comparing the one or more of the plurality of ultrasound images with the baseline image; and determining intrafractional movement of at least one of the target tissue or the surrounding tissue based on the compared one or more ultrasound images as the radiation fraction is delivered to the patient by the radiation therapy device. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
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Specification