Delivering and/or receiving material with respect to a subject surface

• US 10,543,310 B2
• Filed: 11/11/2016
• Issued: 01/28/2020
• Est. Priority Date: 12/19/2011
• Status: Active Grant

• Current Assignee: Yourbio Health Incorporated
• Original Assignee: Seventh Sense Biosystems, Inc.
• Inventors: Bernstein, Howard, Chickering, III, Donald E., Gong, Ping, Davis, Shawn
• Primary Examiner(s): Hayman, Imani N
• Assistant Examiner(s): Legette, Tiffany
• Application Number:
  US15/349,090
• Publication Number:
  US 20170281852A1
• Time in Patent Office: 1,173 Days
• CPC Class Codes: A61B 5/150022 for capillary blood or interstitial fluid
• CPC Class Codes: A61B 5/150099 by negative pressure, other than vacuum extraction into a syringe by pulling on the piston rod or into pre-evacuated tubes
• CPC Class Codes: A61B 5/150412 Pointed piercing elements, e.g. needles, lancets for piercing the skin blade-like piercing elements A61B5/150442
• CPC Class Codes: A61B 5/150969 Low-profile devices which resemble patches or plasters, e.g. also allowing collection of blood samples for testing
• CPC Class Codes: A61B 5/150984 Microneedles or microblades
• CPC Class Codes: A61B 5/15113 Manually triggered, i.e. the triggering requires a deliberate action by the user such as pressing a drive button
• CPC Class Codes: A61B 5/15188 Constructional features of reusable driving devices
• CPC Class Codes: A61M 1/38 Removing constituents from donor blood and storing or returning remainder to body , e.g. for transfusion
• CPC Class Codes: A61M 2037/0023 Drug applicators using microneedles
• CPC Class Codes: A61M 37/0015 by using microneedles
• CPC Class Codes: A61M 5/00 Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests vaccination appliances for veterinary use A61D1/025 ; tube connectors, tube couplings, valves or branch units specially adapted for medical use A61M39/00; containers specially adapted for medical or pharmaceutical purposes A61J1/00; combinations of vial and syringe for mixing or transferring their contents A61J1/20; holders for containers for collecting, storing or administering blood or medical fluids A61J1/16

Abstract

The present invention generally relates to receiving bodily fluid through a device opening. In one aspect, the device includes a flow activator arranged to cause fluid to be released from a subject. The flow activator may be actuated in a deployment direction by a deployment actuator, which may in turn cause fluid release from a subject. The flow activator may also be moved in a retraction direction by a retraction actuator. In one aspect, the device may include a vacuum source that may help facilitate fluid flow into the opening of the device and/or may help facilitate fluid flow from the opening to a storage chamber. In one aspect, an effector may enable fluid communication between the opening and the vacuum source and may do so in response to actuation of the flow activator.

Claims

1. A drug delivery device, including:

a flow activator arranged to cause delivery of a material to a subject and/or to cause release of blood or other material from the subject, the flow activator including one or more needles arranged to penetrate skin of a subject; and

a material source comprising a reservoir containing a drug prior to actuation of the device, the reservoir being configured to be penetrated by the one or more needles for delivery of the drug in the reservoir to the subject in response to actuation of the device,

wherein the one or more needles do not penetrate the reservoir prior to actuation of the device,

and wherein the one or more needles move distally through the reservoir toward the skin of the subject in response to actuation of the device.

2. The device of claim 1, wherein the reservoir includes a drug eluting hydrogel arranged to release the drug for delivery to skin openings formed by the one or more needles.

3. The device of claim 1 wherein penetration of the reservoir by the one or more needles causes an exterior surface of the one or more needles to be coated by the drug in the reservoir.

4. The device of claim 1, wherein the reservoir includes a dissolvable material.

5. The device of claim 1, wherein the one or more needles are hollow and the material is forced through the one or more needles and into a subject surface penetrated by the one or more needles.

6. The device of claim 1, further comprising a positive pressure source arranged to force the drug from the reservoir.

7. The device of claim 1, wherein actuation of the device causes the one or more needles to penetrate the reservoir prior to penetrating the skin or other surface of the subject.

8. The device of claim 1, wherein the one or more needles penetrate completely through the reservoir in response to actuation of the device.

9. The device of claim 1, further comprising a device actuator, wherein actuation of the device actuator causes the one or more needles to move downwardly toward the skin of the subject and penetrate the reservoir to deliver the drug in the reservoir to the subject.

10. The device of claim 9, further comprising an effector, wherein actuation of the device actuator causes the effector to deploy the one or more needles to move relative to the reservoir toward the skin or other surface of the subject.

11. The device of claim 10, wherein the effector comprises a snap dome actuator.

12. A drug delivery device, including:

a flow activator arranged to cause delivery of a material to a subject and/or to cause release of blood or other material from the subject, the flow activator including one or more needles arranged to penetrate skin of a subject; and

a material source comprising a reservoir containing a drug prior to actuation of the device, the reservoir being configured to be penetrated by the one or more needles for delivery of the drug in the reservoir to the subject in response to actuation of the device,

wherein the one or more needles do not penetrate the reservoir prior to actuation of the device, and

wherein penetration of the reservoir by the one or more needles causes an exterior surface of the one or more needles to be coated by the drug in the reservoir.

13. The device of claim 12, wherein the reservoir includes a drug eluting hydrogel arranged to release the drug for delivery to skin openings formed by the one or more needles.

14. The device of claim 12, wherein the reservoir includes a dissolvable material.

15. The device of claim 12, further comprising:

a device actuator, wherein actuation of the device actuator causes the one or more needles to move downwardly toward the skin of the subject and penetrate the reservoir to deliver the drug in the reservoir to the subject; and

an effector, wherein actuation of the device actuator causes the effector to deploy the one or more needles to move relative to the reservoir toward the skin or other surface of the subject.

16. The device of claim 15, wherein the effector comprises a snap dome actuator.