Non-invasive optical measurement of blood analyte
First Claim
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1. A method comprising:
- receiving, by a processing system from a light detector, information associated with first optical signals detected by the light detector, wherein the first optical signals are detected from a first area illuminated by a light source, wherein the first area includes a blood vessel, and wherein the blood vessel is proximate to a surface of an exposed body part; and
determining, by the processing system, a concentration of a blood analyte based on the received information associated with the first optical signals, wherein determining the concentration of the blood analyte comprises;
determining a first light absorption profile from the information associated with the first optical signals detected by the light detector from an area including the blood vessel;
detecting a size of the blood vessel;
comparing the first light absorption profile to a plurality of pre-determined light absorption profiles having known blood analyte concentrations; and
calibrating a determined relative analyte concentration based on the size of the blood vessel.
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Abstract
Methods and devices for accurate noninvasive measurement of blood analyte concentrations are disclosed. In an example process, optical properties of a blood vessel proximate to the surface of an exposed body part, for example, the sclera or the backside of the eyelid, is measured. Analyte concentrations are determined based on the measured optical properties.
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Citations
19 Claims
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1. A method comprising:
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receiving, by a processing system from a light detector, information associated with first optical signals detected by the light detector, wherein the first optical signals are detected from a first area illuminated by a light source, wherein the first area includes a blood vessel, and wherein the blood vessel is proximate to a surface of an exposed body part; and determining, by the processing system, a concentration of a blood analyte based on the received information associated with the first optical signals, wherein determining the concentration of the blood analyte comprises; determining a first light absorption profile from the information associated with the first optical signals detected by the light detector from an area including the blood vessel; detecting a size of the blood vessel; comparing the first light absorption profile to a plurality of pre-determined light absorption profiles having known blood analyte concentrations; and calibrating a determined relative analyte concentration based on the size of the blood vessel. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A non-invasive analyte detection device comprising:
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a light source configured to illuminate a first area, wherein the first area includes a blood vessel, and wherein the blood vessel is proximate to a surface of an exposed body part; a light detector configured to detect first optical signals from the first area; and a processor configured to; receive information associated with the first optical signals; determine a first light absorption profile from the received information associated with the first optical signals determine a size of the blood vessel; and determine a concentration of a blood analyte based on the first light absorption profile and the size of the blood vessel. - View Dependent Claims (13, 14, 15, 16, 17, 18, 19)
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Specification