High pressure pre-burst for improved fluid delivery
First Claim
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1. A device, comprising:
- a hollow needle having a lumen and a plurality of injection ports comprising at least a first injection port, port A1, a second injection port, port A2, and a third injection port, port A3,wherein each of the plurality of injection ports increase in diameter from the proximal to the distal region of the needle, with said port A3 having an area greater than an area of said port A2 and the area of said port A2 being greater than an area of said port A1,wherein Σ
A1≥
Aneedle, and Aneedle is the cross-sectional area of the needle and Ai is the cross-sectional area of the plurality of injection ports,a plurality of individual channels within the lumen of the needle, the plurality of individual channels being oriented substantially parallel to a central longitudinal axis of the needle, wherein each of the plurality of injection ports is in fluid communication with one of the plurality of individual channels disposed within the lumen of the needle.
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Abstract
A needle with multiple injection ports is used in connection with a high-pressure injection system to infuse a treatment solution into a treatment area below the dermis of the skin. The needle has multiple tines that extend outwardly from the injection ports while inside the treatment area to disrupt tissue in the treatment area and to create multiple pathways of infusion. The tines are withdrawn and the needle is partially withdrawn, and solution is injected from the needle into the treatment area at high pressure to infuse the tissue within the treatment area. The burst, infusion, and a treatment such as an energy or third solution may be interleaved and repeated multiple times.
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Citations
16 Claims
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1. A device, comprising:
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a hollow needle having a lumen and a plurality of injection ports comprising at least a first injection port, port A1, a second injection port, port A2, and a third injection port, port A3, wherein each of the plurality of injection ports increase in diameter from the proximal to the distal region of the needle, with said port A3 having an area greater than an area of said port A2 and the area of said port A2 being greater than an area of said port A1, wherein Σ
A1≥
Aneedle, and Aneedle is the cross-sectional area of the needle and Ai is the cross-sectional area of the plurality of injection ports,a plurality of individual channels within the lumen of the needle, the plurality of individual channels being oriented substantially parallel to a central longitudinal axis of the needle, wherein each of the plurality of injection ports is in fluid communication with one of the plurality of individual channels disposed within the lumen of the needle. - View Dependent Claims (2, 3, 4, 5, 6, 7)
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8. A device, comprising:
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a hollow needle having a lumen and a plurality of injection ports comprising at least a first injection port, port A1, a second injection port, port A2, and a third injection port, port A3, wherein said port A1 is positioned in a proximal region of the needle, said port A3 is positioned in a distal region of the needle, said port A2 is positioned between said port A1 and said port A3, each of the plurality of injection ports extending through an outer surface of the needle and in fluid connection with the lumen, and said port A3 is the distal-most port that extends through the outer surface of the needle; and wherein each of the plurality of injection ports increase in diameter from the proximal to the distal region of the needle, with said port A3 having an area greater than an area of said port A2 and the area of said port A2 being greater than an area of said port A1, wherein Σ
Ai≥
Aneedle, and Aneedle is the cross-sectional area of the needle and Ai is the cross-sectional area of the plurality of injection ports;a compressor system in fluidic connection with the needle and configured to pressurize a fluid to be delivered to a destination via the plurality of injection ports, wherein a placement and cross-sectional area of the plurality of injection ports relative to the needle enables delivery of a volume of the fluid of between 0.1 mL and 20 mL at a pressure between 1 to 200 pounds per square inch and in a plane parallel to a skin surface, when the needle is inserted percutaneously and parallel to the overall surface of the skin, and a plurality of individual channels within the lumen of the needle, wherein each of the plurality of injection ports is in fluid communication with a corresponding one of the plurality of channels and wherein the plurality of individual channels are each oriented substantially parallel to a central longitudinal axis of the needle. - View Dependent Claims (9)
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10. A device, comprising:
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a hollow needle having a lumen and a plurality of injection ports comprising at least a first injection port, port A1, a second injection port, port A2, and a third injection port, port A3, wherein said port A1 is positioned in a proximal region of the needle, said port A3 is positioned in a distal region of the needle, said port A2 is positioned between said port A1 and said port A3, each of the plurality of injection ports extending through an outer surface of the needle and in fluid connection with the lumen, and said port A3 is the distal-most port that extends through the outer surface of the needle; and wherein each of the plurality of injection ports increase in diameter from the proximal to the distal region of the needle, with said port A3 having an area greater than an area of said port A2 and the area of said port A2 being greater than an area of said port A1, wherein Σ
A1≥
Aneedle, and Aneedle is the cross-sectional area of the needle and Ai is the cross-sectional area of the plurality of injection ports; anda plurality of individual channels within the lumen of the needle, wherein each one of the plurality of individual channels is in fluid communication with a corresponding one of the plurality of injection ports, and wherein each one of the plurality of individual channels is oriented substantially parallel to a central longitudinal axis of the needle. - View Dependent Claims (11, 12, 13, 14, 15, 16)
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Specification