Plasticized PVC admixtures with surface modifying macromolecules and articles made therefrom

• US 10,557,030 B2
• Filed: 04/17/2019
• Issued: 02/11/2020
• Est. Priority Date: 10/18/2016
• Status: Active Grant

• Current Assignee: Evonik Canada Inc. (Rag-Stiftung)
• Original Assignee: Evonik Canada Inc. (Rag-Stiftung)
• Inventors: Chang, Weilun, Ho, Jeannette, Santerre, J. Paul, Mullick, Sanjoy
• Primary Examiner(s): Mulcahy, Peter D.
• Application Number:
  US16/386,409
• Publication Number:
  US 20190248995A1
• Time in Patent Office: 300 Days
• CPC Class Codes: A61L 2420/02 Methods for coating medical devices
• CPC Class Codes: A61L 27/48 with macromolecular fillers
• CPC Class Codes: A61L 27/502 Plasticizers
• CPC Class Codes: C08J 2327/06 Homopolymers or copolymers of vinyl chloride
• CPC Class Codes: C08J 2475/08 from polyethers
• CPC Class Codes: C08J 3/18 Plasticising macromolecular compounds plasticisers C08K
• CPC Class Codes: C08K 5/0016 Plasticisers
• CPC Class Codes: C08K 5/12 of cyclic polycarboxylic acids
• CPC Class Codes: C08L 2201/10 Transparent films; Clear coatings; Transparent materials
• CPC Class Codes: C08L 2205/06 having improved processability or containing aids for moulding methods
• CPC Class Codes: C08L 27/06 Homopolymers or copolymers of vinyl chloride
• CPC Class Codes: C08L 75/06 from polyesters

Abstract

The present invention relates to polyvinvyl chloride (PVC) admixtures with plasticizers and surface modifying macromolecules. In accordance with embodiments, articles formed from the compositions disclosed herein may reduce leaching of plasticizers.

Claims

1. A blended composition comprising from 50% to 99.9% (w/w) of a polyvinyl chloride base polymer, from 10% to 50% (w/w) of a plasticizer that is di-(2-ethylhexyl)phthalate (DEHP), and from 0.01% to 20% (w/w) of a surface modifying macromolecule (SMM) described by the formula:

F_T-[B-A]_n-B-F_T,

where

(i) A comprises poly(diethylene glycol)adipate, (neopentyl glycol-ortho phthalic anhydride) polyester, (diethylene glycol-ortho phthalic anhydride) polyester, (1,6-hexanediol-ortho phthalic anhydride) polyester, polypropylene oxide, polyethylene oxide, or polytetramethylene oxide;

(ii) B comprises a urethane;

(iii) F_T is a polyfluoroorgano group, and

(iv) n is an integer from 1 to 10.

2. The composition of claim 1, wherein the composition comprises 20% to 45% (w/w) DEHP.

3. The composition of claim 1, wherein the amounts of said polyvinyl chloride base polymer, said plasticizer, and SMM provide a miscible admixture.

4. The composition of claim 1, wherein said composition comprises from 60% to 80% (w/w) of said polyvinyl chloride base polymer, from 20% to 40% (w/w) of said DEHP, and from 0.5% to 5% (w/w) of said SMM.

5. The composition of claim 1, further comprising one or more additives selected from the group consisting of a heat stabilizer, an impact modifier, a process aid, a lubricant, a filler, a flame retardant, a pigment, a blowing agent, a biocide, a viscosity modifier, an antistatic agent, an antioxidant, a UV absorber, an antifogging agent, and a bonding agent.

6. An article comprising the composition of claim 1.

7. The article of claim 6, wherein said article is transparent.

8. The article of claim 7, wherein said article is an implantable device.

9. The article of claim 8, wherein said implantable device contacts body fluids.

10. The article of claim 8, wherein said implantable device is in contact with fluids that enter the body.

11. The article of claim 7, wherein said article is PVC tubing or a PVC bag.

12. The article of claim 6, wherein said article exhibits reduced leaching of said plasticizing agent.

13. The article of claim 12, wherein said article has a hardness value on the shore A scale or the shore D scale.

14. The article of claim 13, wherein said article has a hardness value of between 60A and 85D.

15. A method for making an article comprising the steps of:

(a) preparing said blended composition of claim 1; and

(b) processing said composition to form or to coat said article.

16. The method of claim 15, wherein said processing comprises one or more of extruding, injection molding, calendaring, mixing, spraying, dipping, or casting said composition.

17. The method of claim 15, wherein said article is transparent.

18. The method of claim 15, wherein said article exhibits reduced leaching of said plasticizing agent.

19. The composition of claim 1, wherein the composition comprises 1.0%±

0.5% of said SMM.

20. The composition of claim 1, wherein the composition comprises 2.0%±

0.5% of said SMM.

21. The composition of claim 1, wherein the composition comprises 5.0%±

2.0% of said SMM.

22. The composition of claim 1, wherein A comprises polypropylene oxide and B is formed from hexamethylene diisocyanate.

23. The composition of claim 1, wherein A comprises poly(diethylene glycol)adipate and B is formed from 4,4′

-methylene bis(cyclohexyl isocyanate).

24. The composition of claim 1, wherein A comprises diethylene glycol-ortho phthalic anhydride and B is formed from 4,4′

-methylene bis(cyclohexyl isocyanate).