Methods of lag-compensation for analyte measurements, and devices related thereto
First Claim
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1. A system comprising:
- an on-body unit configured for positioning on a subject, the on-body unit comprising an in vivo positionable glucose sensor; and
an analyte processing unit comprising;
a processor,a display for communicating lag compensated glucose level, wherein the lag compensated glucose level correlates with the subject'"'"'s blood glucose level at an initial reference time, anda memory comprising machine-executable instructions stored thereon for lag compensation of glucose level measurements, the instructions when executed cause the processor to;
receive at least three uncompensated glucose measurements prior to lag compensation, wherein the three uncompensated glucose measurements including a first uncompensated glucose measurement at the initial reference time, a second uncompensated glucose measurement at a first prior reference time, and a third uncompensated glucose measurement at a second prior reference time; and
determine a first scaled rate-of-change by multiplying a first weighting coefficient on a first rate of change computed from the first uncompensated glucose measurement at the initial reference time to the second uncompensated glucose measurement at the first prior reference time and determine a second scaled rate-of-change by multiplying a second weighting coefficient on a second rate of change computed from the first uncompensated glucose measurement at the initial reference time to the second uncompensated glucose measurement at the second prior reference time; and
calculate lag-compensated glucose level measurements from the uncompensated glucose measurements by adding the first scaled rate-of-change, the second scaled rate-of-change, and the first uncompensated glucose measurement.
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Abstract
In some aspects, methods of lag compensation of analyte measurements are provided. Methods of lag-compensation are provided for analyte point measurements and/or for analyte rate-of-change measurements. The methods include receiving a series of uncompensated analyte measurements and determining parameter values for analyte point and/or rate-of-change estimates based on reference analyte measurements. The analyte rate-of-change estimate is based on a sum of a plurality of scaled rates-of-changes. The analyte point estimate is based on a sum of an analyte point and a sum of a plurality of scaled rates-of-changes. Devices related to the methods are also provided.
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21 Claims
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1. A system comprising:
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an on-body unit configured for positioning on a subject, the on-body unit comprising an in vivo positionable glucose sensor; and an analyte processing unit comprising; a processor, a display for communicating lag compensated glucose level, wherein the lag compensated glucose level correlates with the subject'"'"'s blood glucose level at an initial reference time, and a memory comprising machine-executable instructions stored thereon for lag compensation of glucose level measurements, the instructions when executed cause the processor to; receive at least three uncompensated glucose measurements prior to lag compensation, wherein the three uncompensated glucose measurements including a first uncompensated glucose measurement at the initial reference time, a second uncompensated glucose measurement at a first prior reference time, and a third uncompensated glucose measurement at a second prior reference time; and determine a first scaled rate-of-change by multiplying a first weighting coefficient on a first rate of change computed from the first uncompensated glucose measurement at the initial reference time to the second uncompensated glucose measurement at the first prior reference time and determine a second scaled rate-of-change by multiplying a second weighting coefficient on a second rate of change computed from the first uncompensated glucose measurement at the initial reference time to the second uncompensated glucose measurement at the second prior reference time; and calculate lag-compensated glucose level measurements from the uncompensated glucose measurements by adding the first scaled rate-of-change, the second scaled rate-of-change, and the first uncompensated glucose measurement. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21)
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Specification