Coatings containing polymer modified enzyme for stable self-cleaning of organic stains

• US 10,563,094 B2
• Filed: 07/29/2015
• Issued: 02/18/2020
• Est. Priority Date: 09/09/2011
• Status: Active Grant

• Current Assignee: Toyota Motor Corporation, Regents of The University of Minnesota (University of Minnesota)
• Original Assignee: Toyota Motor Engineering & Manufacturing North America Incorporated (Toyota Motor Corporation)
• Inventors: Jia, Hongfei, Wang, Ping, Zhang, Liting, Buthe, Andreas, Zhao, Xueyan, Wu, Songtao, Ishii, Masahiko, Zhang, Minjuan
• Primary Examiner(s): Yamasaki, Robert J
• Assistant Examiner(s): Constantine, Charles Zolton
• Application Number:
  US14/812,087
• Publication Number:
  US 20160024349A1
• Time in Patent Office: 1,665 Days
• Field of Search: None
• CPC Class Codes: A61K 47/60 the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
• CPC Class Codes: C08G 65/33337 cyclic
• CPC Class Codes: C08L 2203/02 for biomedical use
• CPC Class Codes: C08L 2205/02 containing two or more polymers of the same C08L -group
• CPC Class Codes: C09D 175/16 having terminal carbon-to-carbon unsaturated bonds
• CPC Class Codes: C09D 189/00 Coating compositions based on proteins; Coating compositions based on derivatives thereof foodstuff preparations A23J3/00
• CPC Class Codes: C09D 5/024 characterised by the additives
• CPC Class Codes: C09D 5/16 Antifouling paints; Underwater paints
• CPC Class Codes: C09D 7/40 Additives
• CPC Class Codes: C12N 11/06 attached to the carrier via a bridging agent
• CPC Class Codes: C12N 11/089 obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
• CPC Class Codes: C12N 9/14 Hydrolases (3)
• CPC Class Codes: C12N 9/20 Triglyceride splitting, e.g. by means of lipase
• CPC Class Codes: C12N 9/2408 acting on alpha -1,4-glucosidic bonds
• CPC Class Codes: C12N 9/2411 Amylases
• CPC Class Codes: C12N 9/54 bacteria being Bacillus
• CPC Class Codes: C12N 9/96 Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates

Abstract

Bioactive coatings that are stabilized against inactivation by weathering are provided including a base associated with a chemically modified enzyme, and, optionally a first polyoxyethylene present in the base and independent of the enzyme. The coatings are optionally overlayered onto a substrate to form an active coating facilitating the removal of organic stains or organic material from food, insects, or the environment.

Claims

1. A water-stabilized active coating composition comprising:

a polyurethane base in the form of a continuous film, the base formed from a two component solvent borne composition;

a chemically modified enzyme dispersed within said base, said enzyme being covalently modified with one or more molecules of a first polyoxyethylene,

wherein said enzyme is dispersed in said base as aggregates of said chemically modified enzyme, said aggregates having an average particle diameter of up to 5 micrometers,

wherein said aggregates are formed by adding a solution of said chemically modified enzyme to the two component solvent borne composition prior to formation of the continuous film, and allowing the chemically modified enzyme molecules to aggregate together to form the aggregates.

2. The coating composition of claim 1 wherein said first polyoxyethylene has a molecular weight of 10,000 Daltons or greater.

3. The coating composition of claim 1 wherein said first polyoxyethylene is a branched molecule.