System and method for generating a 2D image using mammography and/or tomosynthesis image data

• US 10,573,276 B2
• Filed: 06/20/2018
• Issued: 02/25/2020
• Est. Priority Date: 11/27/2011
• Status: Active Grant

• Current Assignee: Hologic Incorporated
• Original Assignee: Hologic Incorporated
• Inventors: Kreeger, Kevin, Smith, Andrew P., Kshirsagar, Ashwini, Ge, Jun, Zhang, Yiheng, Chui, Haili, Ruth, Christopher, Zhang, Xiangwei, Wei, Liyang, Stein, Jay
• Primary Examiner(s): Brier, Jeffery A
• Application Number:
  US16/013,701
• Publication Number:
  US 20190043456A1
• Time in Patent Office: 615 Days
• CPC Class Codes: A61B 6/025 Tomosynthesis
• CPC Class Codes: A61B 6/502 for diagnosis of breast, i.e. mammography
• CPC Class Codes: A61B 6/5205 involving processing of raw data to produce diagnostic data
• CPC Class Codes: A61B 6/5235 combining images from the same or different ionising radiation imaging techniques, e.g. PET and CT
• CPC Class Codes: A61B 6/5241 combining overlapping images of the same imaging modality, e.g. by stitching
• CPC Class Codes: G06T 11/006 Inverse problem, transformation from projection-space into object-space, e.g. transform methods, back-projection, algebraic methods
• CPC Class Codes: G06T 11/008 Specific post-processing after tomographic reconstruction, e.g. voxelisation, metal artifact correction
• CPC Class Codes: G06T 2207/10081 Computed x-ray tomography [CT]
• CPC Class Codes: G06T 2207/20221 Image fusion; Image merging
• CPC Class Codes: G06T 2207/30068 Mammography; Breast
• CPC Class Codes: G06T 2211/436 Limited angle
• CPC Class Codes: G06T 7/30 Determination of transform parameters for the alignment of images, i.e. image registration
• CPC Class Codes: G09G 5/377 for mixing or overlaying two or more graphic patterns G09G5/02, G09G5/397 take precedence

Abstract

The invention includes a method including the steps of obtaining a plurality of images, each of the images in the plurality having at least one corresponding region, generating a merged image, the merged image also having the corresponding region. The step of generating includes selecting an image source from the plurality of images to source image data for the corresponding region in the merged image by comparing attributes of the corresponding regions of the plurality of images to identify the image source having preferred attributes.

Claims

1. A method, comprising:

obtaining a plurality of images, each of the images in the plurality having at least one corresponding region;

generating a synthesized 2D mammography image, the synthesized 2D mammography image also having the corresponding region, wherein the synthesized 2D mammography image is generated by

selecting an image source from the plurality of images to source image data for the at least one corresponding region in the synthesized 2D mammography image by comparing attributes of the at least one corresponding region in one or more of the plurality of images to identify the image source having preferred attributes;

generating a map for the synthesized 2D mammography image, whereby the map identifies at least one of the plurality of images that sourced the corresponding region in the synthesized 2D mammography image; and

displaying at least one of the synthesized 2D mammography image and the source image data for the at least one corresponding region.

2. The method of claim 1, wherein the preferred attributes include attributes indicative of potential cancers.

3. The method of claim 1 further comprising filtering the plurality of images to magnify attributes of the plurality of images.

4. The method of claim 3, wherein filtering applies different filters to images of different types.

5. The method of claim 1 further comprising visually indicating a distribution of the preferred attributes in the corresponding region by providing a histogram to illustrate a depth of the preferred attributes.

6. The method of claim 1, wherein the plurality of images include 3D projection or reconstruction images.

7. The method of claim 1, wherein the plurality of images is selected from a group consisting of tomosynthesis projection images, reconstructed tomosynthesis slices, mammograms, and synthesized two dimensional images.

8. The method of claim 1, wherein the at least one of the plurality of images that sourced the at least one region overlays the synthesized 2D mammography image such that a user can view both types of images at the same time or by toggling between the types.

9. A display workstation, comprising:

a processor;

a display station operatively coupled with the processor; and

an interface operatively coupled with the processor, wherein the respective processor and interface are configured to allow a user to selectively cause the processor to

obtain a plurality of images, each of the images in the plurality having at least one corresponding region,

generate a synthesized 2D mammography image having the at least one corresponding region, wherein the synthesized 2D mammography image is a synthesized mammography image that is generated by selecting an image source from the plurality of images to source image data for the at least one corresponding region in the synthesized 2D mammography image by comparing attributes of the at least one corresponding region in each of the plurality of images to identify the image source having preferred attributes,

generate a map for a user-selected region in the synthesized 2D mammography image, whereby the map identifies at least one of the plurality of images that sourced the user-selected region in the synthesized 2D mammography image, and

display on the display station the at least one of the plurality of images that sourced the user-selected region when the user-selected region is selected by the user,

the interface further configured to allow a user to selectively cause the processor to display three-dimensional information related to a selected region of the synthesized 2D mammography image on the display station.

10. The display workstation of claim 9, wherein the interface includes a mode selection mechanism enabling a user to select a mode of either generation or display of the synthesized 2D mammography image on the display station.

11. The display workstation of claim 9, wherein the interface allows a user to view both of or toggle between the synthesized 2D mammography image and the one of the group of images that sourced the at least one of the plurality of regions.

12. A display workstation, comprising:

a processor;

a display station operatively coupled with the processor; and

an interface operatively coupled with the processor, wherein the interface is configured to allow a user to selectively cause the processor to generate and display a synthesized 2D mammography image on the display station, the synthesized 2D mammography image comprising a two dimensional synthesized image comprising a plurality of regions, wherein at least two of the regions are sourced from different images selected from a group of images, and wherein the group of images include tomosynthesis projection images, tomosynthesis reconstruction slices, mammograms and synthesized 2D images,

the interface further configured to allow a user to selectively cause the processor to display three-dimensional information related to a selected region of the synthesized 2D mammography image on the display station,

wherein the interface provides a graphical indicator along with a display of the synthesized 2D mammography image such that the graphical indicator illustrates a depth of attributes within the regions.

13. The display workstation of claim 12, wherein the interface allows a user to cause the processor to display simultaneously, sequentially, or in toggle mode, two or more of the synthesized 2D mammography image, a tomosynthesis projection image, a tomosynthesis reconstruction slice, a mammogram, and a synthesized 2D image.