Apparatus for performing peritoneal ultrafiltration

• US 10,576,195 B2
• Filed: 11/20/2015
• Issued: 03/03/2020
• Est. Priority Date: 11/21/2014
• Status: Active Grant

• Current Assignee: Triomed AB
• Original Assignee: Triomed AB
• Inventors: Axelsson, Mikael, Landholm, Stefan, Persson, Eva, Bengtsson, Hans
• Primary Examiner(s): Hayman, Imani N
• Application Number:
  US15/528,434
• Publication Number:
  US 20170281848A1
• Time in Patent Office: 1,565 Days
• CPC Class Codes: A61M 1/1566 Means for adding solutions or substances to the treating fluid
• CPC Class Codes: A61M 1/159 specially adapted for peritoneal dialysis
• CPC Class Codes: A61M 1/28 Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
• CPC Class Codes: A61M 1/281 Instillation other than by gravity
• CPC Class Codes: A61M 1/282 Operational modes
• CPC Class Codes: A61M 1/287 Dialysates therefor
• CPC Class Codes: A61M 1/288 Priming priming in extracorporeal blood circuits A61M1/3643
• CPC Class Codes: A61M 2205/07 having air pumping means
• CPC Class Codes: A61M 2205/12 with interchangeable cassettes forming partially or totally the fluid circuit
• CPC Class Codes: A61M 2205/3331 Pressure; Flow
• CPC Class Codes: A61M 2205/3334 Measuring or controlling the flow rate
• CPC Class Codes: A61M 2205/8206 battery-operated
• CPC Class Codes: B01D 61/243 Dialysis

Abstract

An apparatus for ultrafiltration of a patient being overhydrated due to congestive heart failure, comprising a tube set including a connector for connection to a patient line for access to the peritoneal cavity of the patient. A flow pump is arranged for addition and removal outflow and inflow (recirculation) of fluid from/to the peritoneal cavity. An osmotic agent peristaltic pump is arranged for replenishment of glucose solution to the fluid added to the peritoneal cavity for promoting ultrafiltration. The glucose is replenished intermittently for keeping a concentration of glucose substantially constant in the peritoneal cavity. The flow pump comprises a pressure chamber with rigid walls and a flexible pump bag arranged therein. An air pump pressurizes the chamber for outflow of fluid from the peritoneal cavity by a sub pressure and inflow of fluid to the peritoneal cavity by an overpressure, which pressures are maintained within safe limits.

Claims

1. An apparatus for ultrafiltration of a patient in need thereof, comprising

a patient tube comprising a connector for connection to a patient line for access to a fluid installed in a peritoneal cavity of the patient;

a flow pump comprising a pressure chamber having rigid walls and a pump bag arranged inside said pressure chamber and an air pump for generating a negative pressure inside said pressure chamber for removal of fluid in an outflow from said peritoneal cavity into said pump bag, and for generating a positive pressure for introduction of fluid in an inflow from said pump bag to the peritoneal cavity;

a glucose bag, comprising concentrated glucose solution and a glucose tube connected to said patient tube;

a glucose pump arranged in said glucose tube for addition of concentrated glucose from said glucose bag into said outflow of fluid by said flow pump;

whereby the glucose is diluted and replenished intermittently.

2. The apparatus according to claim 1, wherein said glucose bag comprises glucose at a concentration of 10%, 15%, 20%, 25%, 35% or 40% or 50%, and wherein the glucose is diluted to a final concentration of less than 3% before addition to the peritoneal cavity.

3. The apparatus according to claim 1, further comprising a flow meter for measuring the flow rate of said inflow or outflow fluid.

4. The apparatus according to claim 1, further comprising:

a cassette in which the flow of glucose from the glucose bag is diluted by said outflow of fluid.

5. The apparatus according to claim 4, further comprising

a fluid pressure meter connected to the cassette for sensing the pressure during said inflow and/or said outflow and for emitting an alarm if the pressure exceeds a first predetermined level.

6. The apparatus according to claim 5, wherein the fluid pressure meter is arranged to measure the pressure in the cassette before said inflow to the peritoneal cavity as an indication of the pressure in the peritoneal cavity and to emit an alarm if the pressure is above a second predetermined pressure.

7. The apparatus according to claim 5, wherein an air pressure meter is arranged in said pressure chamber and is arranged to compare the pressure inside said pressure chamber with the pressure in said cassette for indicating a flow when the pressure difference is smaller than a third predetermined value.

8. The apparatus according to claim 6, wherein an air pressure meter is arranged in said pressure chamber and is arranged to compare the pressure inside said pressure chamber with the pressure in said cassette for indicating a flow when the pressure difference is smaller than a third predetermined value.

9. The apparatus according to claim 1, wherein an air pressure meter in said pressure chamber is arranged to indicate when the pump bag is filled by:

measuring a decrease of pressure chamber pressure to an outflow pressure;

measuring a constant pressure chamber pressure during said outflow;

measuring a decrease of pressure chamber pressure to a minimum pressure after said outflow;

wherein an evaluation device is arranged to indicate an error if a time period of constant outflow chamber pressure is less than a predetermined time period.

10. The apparatus according to claim 1, wherein an air pressure meter in said pressure chamber is arranged to indicate when the pump bag is empty by:

measuring an increase of pressure chamber pressure to an inflow pressure;

measuring a constant pressure chamber pressure during said inflow;

measuring an increase of pressure chamber pressure to a maximum pressure after said inflow;

wherein an evaluation device is arranged to indicate an error if a time period of constant chamber inflow pressure is less than a predetermined time period.