Ocular surface interferometry (OSI) devices and systems for imaging, processing, and/or displaying an ocular tear film
First Claim
1. An apparatus for imaging an ocular tear film, comprising:
- a control system configured to;
(a) receive at least one first image containing optical wave interference of specularly reflected light and a background signal from a region of interest of an ocular tear film captured by an imaging device while illuminated by a multi-wavelength light source; and
(b) receive at least one second image containing the background signal from the region of interest of the ocular tear film captured by the imaging device;
wherein the control system is further configured to control the multi-wavelength light source to produce the specularly reflected light from at least one first portion of the region of interest of the ocular tear film while the multi-wavelength light source obliquely illuminates at least one second portion of the region of interest of the ocular tear film adjacent to the at least one first portion; and
wherein the control system is further configured to control the multi-wavelength light source to produce the specularly reflected light from the at least one second portion of the region of interest of the ocular tear film while the multi-wavelength light source obliquely illuminates the at least one first portion of the region of interest of the ocular tear film adjacent to the at least one second portion.
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Accused Products
Abstract
Ocular surface interferometry devices, systems, and methods are disclosed for imaging an ocular tear film. An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in a first image, wherein the specularly reflected light may be produced from various portions of the ocular tear film by obliquely illuminating various portions of the ocular tear film with a multi-wavelength light source, such as in a tiling pattern(s). The imaging device can also be focused on the lipid layer to capture a second image containing the background signal(s) present in the first image. The second image can be subtracted from the first image to reduce and/or eliminate the background signal(s) in the first image to produce a resulting image, which can used to measure a tear film layer thickness.
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Citations
27 Claims
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1. An apparatus for imaging an ocular tear film, comprising:
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a control system configured to; (a) receive at least one first image containing optical wave interference of specularly reflected light and a background signal from a region of interest of an ocular tear film captured by an imaging device while illuminated by a multi-wavelength light source; and (b) receive at least one second image containing the background signal from the region of interest of the ocular tear film captured by the imaging device; wherein the control system is further configured to control the multi-wavelength light source to produce the specularly reflected light from at least one first portion of the region of interest of the ocular tear film while the multi-wavelength light source obliquely illuminates at least one second portion of the region of interest of the ocular tear film adjacent to the at least one first portion; and wherein the control system is further configured to control the multi-wavelength light source to produce the specularly reflected light from the at least one second portion of the region of interest of the ocular tear film while the multi-wavelength light source obliquely illuminates the at least one first portion of the region of interest of the ocular tear film adjacent to the at least one second portion. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27)
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Specification