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Retrievable self-expanding non-thrombogenic low-profile percutaneous atrioventricular valve prosthesis

  • US 10,583,004 B2
  • Filed: 02/26/2016
  • Issued: 03/10/2020
  • Est. Priority Date: 02/27/2015
  • Status: Active Grant
First Claim
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1. An atrioventricular prosthesis device comprising:

  • a frame disposed on a central member extending along a longitudinal axis thereof, and at least partially defining and enclosing a central cavity, the frame having a distal portion, a proximal portion, and a middle portion connected therebetween, the proximal portion of the frame comprising at least one first collar slidably connected to the central member and a plurality of first elongated members connected to the at least one first collar, the first elongated members extending longitudinally and radially outwardly from the collar to define the central cavity when the frame is in a deployed state; and

    a valve construct formed, at least in part, from a cell growth scaffold, at least partially disposed within the central cavity defined by the frame, the valve construct comprising;

    an annular portion defining an aperture connected to one or more of the plurality of first elongated members for positioning the valve construct within the central cavity of the frame, anda plurality of leaflets extending longitudinally and radially inwardly from the annular portion,wherein the frame and valve construct are transitionable from a contracted state, in which the frame and valve construct are configured to be disposed within a catheter tube, to the deployed state in which a diameter of at least a portion of the frame and the valve construct substantially conforms to a diameter of a tricuspid and/or mitral valve opening.

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