Recirculating dialysate fluid circuit for blood measurement
First Claim
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1. A method for determining an effective clearance of a dialyzer, comprising:
- measuring a first conductivity value of a dialysate flowing from an outlet of the dialyzer not having contacted a urease containing material layer of a sorbent regeneration system;
measuring a second conductivity value of the dialysate flowing from the outlet of the dialyzer after the dialysate has contacted the urease containing material layer of the sorbent regeneration system;
intermittently providing an electrolyte bolus or diluent to a dialysate flow path and measuring a bolus conductivity of the dialysate passing to the dialyzer to provide a third conductivity value;
measuring a bolus conductivity of the dialysate passing from the dialyzer to provide a fourth conductivity value;
measuring a dialysate flow rate; and
determining the effective clearance of the dialyzer from the third and fourth conductivity values.
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Abstract
A blood based solute monitoring system for measuring at least one blood solute species that has a first recirculation flow path in fluid communication with a dialyzer. The first recirculation flow path is configured to allow a fluid to recirculate through a dialyzer such that the concentration of at least one solute species in the fluid becomes equilibrated to the solute species concentration of the blood in a blood compartment of the dialyzer. The blood solute monitoring system has at least one sensor to measure a fluid characteristic.
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Citations
6 Claims
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1. A method for determining an effective clearance of a dialyzer, comprising:
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measuring a first conductivity value of a dialysate flowing from an outlet of the dialyzer not having contacted a urease containing material layer of a sorbent regeneration system; measuring a second conductivity value of the dialysate flowing from the outlet of the dialyzer after the dialysate has contacted the urease containing material layer of the sorbent regeneration system; intermittently providing an electrolyte bolus or diluent to a dialysate flow path and measuring a bolus conductivity of the dialysate passing to the dialyzer to provide a third conductivity value; measuring a bolus conductivity of the dialysate passing from the dialyzer to provide a fourth conductivity value; measuring a dialysate flow rate; and determining the effective clearance of the dialyzer from the third and fourth conductivity values. - View Dependent Claims (2, 3, 4, 5, 6)
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Specification