Method and system for applying stimulation in treating sleep disordered breathing
First Claim
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1. A stimulation system comprising:
- an implantable pulse generator comprising;
a sensing element to receive sensed respiratory effort information;
a stimulation element to apply a stimulation signal to a hypoglossal nerve via a nerve electrode; and
a controller to implement a therapy manager and in communication with at least the sensing element and the stimulation element, wherein the controller comprises a processing resource and a non-transitory computer readable memory storing machine readable instructions, executable via the processing resource, to;
determine, via the therapy manager, an indication of an upper airway flow limitation via the sensed respiratory effort information from the sensing element, wherein the indicated upper airway flow limitation corresponds to at least a partial obstruction of the upper airway flow associated with obstructive sleep apnea; and
determine an obstructive sleep apnea therapy via the therapy manager, via automatically selecting based on the determined indication of the upper airway flow limitation, between at least;
a first nerve stimulation protocol to apply stimulation to the hypoglossal nerve via the stimulation element synchronous with an expiratory phase of a respiratory cycle; and
a second nerve stimulation protocol to apply stimulation to the hypoglossal nerve via the stimulation element during both of a portion of an inspiratory phase of the respiratory cycle and a portion of the expiratory phase,wherein the instructions are to;
automatically select the first nerve stimulation protocol upon determination, via the therapy manager, that the indicated upper airway flow limitation predominantly coincides with the expiratory phase; and
cause application of nerve stimulation via the stimulation module according to the automatically selected first nerve stimulation protocol.
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Abstract
A stimulation protocol determination system includes an input module and a selector module. The input module is provided to receive an indication of an upper airway flow limitation via sensed respiratory effort information. The selection module is provided to automatically select, based on the indicated upper airway flow limitation, a stimulation protocol.
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Citations
27 Claims
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1. A stimulation system comprising:
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an implantable pulse generator comprising; a sensing element to receive sensed respiratory effort information; a stimulation element to apply a stimulation signal to a hypoglossal nerve via a nerve electrode; and a controller to implement a therapy manager and in communication with at least the sensing element and the stimulation element, wherein the controller comprises a processing resource and a non-transitory computer readable memory storing machine readable instructions, executable via the processing resource, to; determine, via the therapy manager, an indication of an upper airway flow limitation via the sensed respiratory effort information from the sensing element, wherein the indicated upper airway flow limitation corresponds to at least a partial obstruction of the upper airway flow associated with obstructive sleep apnea; and determine an obstructive sleep apnea therapy via the therapy manager, via automatically selecting based on the determined indication of the upper airway flow limitation, between at least; a first nerve stimulation protocol to apply stimulation to the hypoglossal nerve via the stimulation element synchronous with an expiratory phase of a respiratory cycle; and a second nerve stimulation protocol to apply stimulation to the hypoglossal nerve via the stimulation element during both of a portion of an inspiratory phase of the respiratory cycle and a portion of the expiratory phase, wherein the instructions are to; automatically select the first nerve stimulation protocol upon determination, via the therapy manager, that the indicated upper airway flow limitation predominantly coincides with the expiratory phase; and cause application of nerve stimulation via the stimulation module according to the automatically selected first nerve stimulation protocol. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
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16. A stimulation system, comprising:
an implantable pulse generator comprising; a sensing element to receive sensed respiratory effort information; a stimulation element to apply a stimulation signal to a hypoglossal nerve via a nerve electrode; and a controller to implement a therapy manager and in communication with at least the sensing element and the stimulation element, wherein the controller comprises a processing resource and a non-transitory computer readable memory storing machine readable instructions, executable via the processing resource, to; determine, via the therapy manager, an indication of an upper airway flow limitation via the sensed respiratory effort information from the sensing element, wherein the indicated upper airway flow limitation corresponds to at least a partial obstruction of the upper airway flow associated with obstructive sleep apnea; and determine an obstructive sleep apnea therapy via the therapy manager, via automatically selecting based on the determined indication of the upper airway flow limitation, between at least; a first nerve stimulation protocol to apply stimulation to the hypoglossal nerve via the stimulation element synchronous with an expiratory phase of a respiratory cycle; and a second nerve stimulation protocol to apply stimulation to the hypoglossal nerve via the stimulation element during both of a portion of an inspiratory phase of the respiratory cycle and a portion of the expiratory phase, wherein the instructions are to; automatically select the second nerve stimulation protocol upon determination, via the therapy manager, that the indicated upper airway flow limitation predominantly coincides with both of a first portion of the inspiratory phase and a first portion of the expiratory phase but does not predominantly coincide with a second portion of inspiratory phase and with a second portion of the expiratory phase; and cause application of nerve stimulation via the stimulation module according to the automatically selected second nerve stimulation protocol. - View Dependent Claims (17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27)
Specification