Clot retrieval device for removing clot from a blood vessel

• US 10,588,648 B2
• Filed: 12/31/2015
• Issued: 03/17/2020
• Est. Priority Date: 03/14/2013
• Status: Active Grant

• Current Assignee: Neuravi Limited (Johnson & Johnson)
• Original Assignee: Neuravi Limited (Johnson & Johnson)
• Inventors: Brady, Eamon, Casey, Brendan, Gilvarry, Michael, Hardiman, David, McArdle, Kevin, Razavi, Mahmood, Vale, David
• Primary Examiner(s): Dornbusch, Dianne
• Application Number:
  US14/985,574
• Publication Number:
  US 20160113663A1
• Time in Patent Office: 1,538 Days
• CPC Class Codes: A61B 17/12109 in a blood vessel
• CPC Class Codes: A61B 17/221 Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions surgical snare instruments A61B17/32056
• CPC Class Codes: A61B 17/320725 with radially expandable cutting or abrading elements A61B17/32075 takes precedence
• CPC Class Codes: A61B 2017/00358 Snares for grasping
• CPC Class Codes: A61B 2017/00778 Operations on blood vessels A61B2017/22097, A61B2017/320741 take precedence
• CPC Class Codes: A61B 2017/22034 for gripping the obstruction or the tissue part from inside
• CPC Class Codes: A61B 2017/2212 having a closed distal end, e.g. a loop
• CPC Class Codes: A61B 2017/2215 having an open distal end
• CPC Class Codes: A61F 2/013 Distal protection devices, i.e. devices placed distally in combination with another endovascular procedure, e.g. angioplasty or stenting
• CPC Class Codes: A61M 29/00 Dilators with or without means for introducing media, e.g. remedies instruments for performing visual medical inspections of cavities or tubes of the body A61B1/00

Abstract

A clot retrieval device 1 for removing occlusive clot from a blood vessel, the device comprises an inner elongate body 3 having a collapsed delivery configuration and an expanded deployed configuration and an outer elongate body 2 at least partially overlying the inner elongate body 2. The outer elongate body 2 is expandable to a radial extent which is greater than the radial extent of the inner body 3 in the deployed configuration to define a clot reception space 11. The outer elongate body 2 comprises a distal end portion 24,49 and the inner elongate body 3 comprises a main body portion 10 and a distal portion which extends in the deployed configuration towards the outer elongate body 2 to a greater extent than the main body portion. The distal portion 10 of the inner elongate member 3 and the distal end portion 24,49 of the outer elongate body 2 together define a three dimensional protective structure to substantially prevent distal egress of clot or clot fragments from the device.

Claims

1. A clot retrieval device for removing clot from a blood vessel, the device having a collapsed delivery configuration and an expanded deployed configuration and comprising:

a framework of struts forming a tubular porous inner body flow channel with a proximal portion and a distal portion; and

a framework of struts forming an outer tubular body having a proximal end located at or adjacent the distal portion of the porous inner body flow channel, the outer tubular body distally tapering from the proximal end and radially surrounding the distal portion of the porous inner body flow channel during both the collapsed delivery configuration and the expanded deployed configuration;

a distal scaffolding zone comprising a plurality of strut elements that form a generally conical tapering with a distal end of the outer tubular body, wherein strut elements of the scaffolding zone comprise a pore size smaller than cells of the tubular porous inner body;

wherein the outer tubular body comprises a plurality of cells that are larger than the cells of the porous inner body flow channel, the outer tubular body being expandable to a radial extent to define a clot reception space.

2. The device of claim 1, wherein a porosity provided by the porous inner body is greater than a porosity provided by the outer tubular body.

3. The device of claim 1, further comprising:

an elongate member having a distal end coupled to a proximal end of the porous inner body at a connection point.

4. The device of claim 3, wherein the connection point is radially offset relative to a longitudinal axis of the outer tubular body.

5. The device of claim 1, wherein the outer tubular body further includes at least one clot inlet mouth positioned between adjacent struts that form of at least one of the cells of the outer tubular body.

6. The device of claim 1, wherein the clot reception space is eccentrically arranged about a longitudinal axis of the outer tubular body.

7. A clot retrieval device for removing clot from a blood vessel, the device having a collapsed delivery configuration and an expanded deployed configuration comprising:

a framework of struts forming an inner body having a tubular main body portion in an expanded configuration, the inner body comprising a proximal portion and a distal portion;

a framework of struts forming an outer tubular body having a proximal end located at or adjacent the distal portion of the inner body, the outer tubular body distally tapering from the proximal end and radially surrounding the distal portion of the inner body during both the collapsed delivery configuration and the expanded deployed configuration,

a distal scaffolding zone comprising a plurality of strut elements that form a generally conical tapering with a distal end of the outer tubular body, wherein strut elements of the scaffolding zone comprise a pore size smaller than cells of the inner body; and

wherein the outer tubular body comprises a plurality of cells that are larger than the cells of the inner body;

wherein a diameter of the tubular main body portion in the expanded deployed configuration is less than 50% of a diameter of the outer tubular body in the expanded deployed configuration along a longitudinally-extending clot reception space between the main body portion of the inner body and the outer tubular body.

8. The device of claim 7, wherein a porosity provided by the inner body is greater than a porosity provided by the outer tubular body.

9. The device of claim 7, further comprising:

an elongate member having a distal end coupled to a proximal end of the inner body at a connection point.

10. The device of claim 9, wherein the connection point is radially offset relative to a longitudinal axis of the outer tubular body.

11. The device of claim 7, wherein the outer tubular body further includes at least one clot inlet mouth positioned between adjacent struts that form of at least one of the cells of the outer tubular body.

12. The device of claim 7, wherein the clot reception space is eccentrically arranged about a longitudinal axis of the outer tubular body.

13. The device of claim 7, wherein strut elements of the distal scaffolding zone are connected to the inner body.

14. The device of claim 7, wherein the distal scaffolding zone forms a fragment capture zone.

15. The device of claim 7, wherein the inner body and the outer tubular body each comprise a mesh-like structure the comprise the cells of the inner body and the outer tubular body.