Clot retrieval device for removing clot from a blood vessel

• US 10,588,649 B2
• Filed: 12/31/2015
• Issued: 03/17/2020
• Est. Priority Date: 03/09/2011
• Status: Active Grant

• Current Assignee: Neuravi Limited (Johnson & Johnson)
• Original Assignee: Neuravi Limited (Johnson & Johnson)
• Inventors: Brady, Eamon, Gilvarry, Michael, Razavi, Mahmood K., Vale, David, Griffin, Patrick, Casey, Brendan, McNamara, Jason
• Primary Examiner(s): Nguyen, Tuan V
• Application Number:
  US14/986,332
• Publication Number:
  US 20160192954A1
• Time in Patent Office: 1,538 Days
• CPC Class Codes: A61B 17/22031 Gripping instruments, e.g. forceps, for removing or smashing calculi A61B17/221 takes precedence
• CPC Class Codes: A61B 17/221 Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions surgical snare instruments A61B17/32056
• CPC Class Codes: A61B 17/320725 with radially expandable cutting or abrading elements A61B17/32075 takes precedence
• CPC Class Codes: A61B 2017/00292 mounted on or guided by flexible, e.g. catheter-like, means
• CPC Class Codes: A61B 2017/00526 Methods of manufacturing
• CPC Class Codes: A61B 2017/00867 shape memory effect for prostheses A61F2210/0014
• CPC Class Codes: A61B 2017/22034 for gripping the obstruction or the tissue part from inside
• CPC Class Codes: A61B 2017/22094 for crossing total occlusions, i.e. piercing
• CPC Class Codes: A61B 2017/2212 having a closed distal end, e.g. a loop
• CPC Class Codes: A61B 2017/2215 having an open distal end
• CPC Class Codes: A61F 2/011 Instruments for their placement or removal
• CPC Class Codes: A61F 2/013 Distal protection devices, i.e. devices placed distally in combination with another endovascular procedure, e.g. angioplasty or stenting
• CPC Class Codes: A61F 2002/016 made from wire-like elements
• CPC Class Codes: A61F 2002/018 made from tubes or sheets of material, e.g. by etching or laser-cutting
• CPC Class Codes: A61F 2230/0069 cylindrical
• CPC Class Codes: A61F 2230/008 paraboloidal
• CPC Class Codes: A61F 2230/0091 helically-coiled or spirally-coiled, i.e. having a 2-D spiral cross-section
• CPC Class Codes: A61F 2230/0093 Umbrella-shaped, e.g. mushroom-shaped

Abstract

A clot retrieval device (9501) for removing clot from a blood vessel comprises an inner elongate body (9503) and an outer elongate body (9504) at least partially overlying the inner elongate body (9503). The device also comprises an elongate member or shaft (9502) having a proximal end which extends exterior of a patient so that a user can retrieve the stent-basket device and captured clot by retracting the shaft (9502). The outer elongate body (9504) and the inner elongate body (9503) are connected to the distal end of the shaft (9502) and are expandable relative to the shaft (9502) from a collapsed delivery configuration to an expanded deployed configuration. The outer elongate body (9504) is expandable relative to the inner elongate body (9503) to a radial extent which is greater than the radial extent of the inner body (9503) in the deployed configuration.

Claims

1. A clot retrieval device for removing clot from a blood vessel, the device having a collapsed delivery configuration and an expanded deployed configuration and comprising:

a shaft extending between a proximal end and a distal end; and

an expandable body extending distally of the distal end of the shaft, the expandable body comprising;

a plurality of clot scaffolding sections connected by hinge elements configured to self-align the clot scaffolding sections for articulating in bends of the vasculature, wherein each hinge element is the only point of contact between respective clot scaffolding sections; and

at least one clot inlet mouth between adjacent clot scaffolding sections,

wherein regions of the plurality of clot scaffolding sections are configured to exert an outward radial force on the clot to urge the clot towards the at least one clot inlet mouth; and

wherein the expandable body comprises a plurality of struts and at least some of the plurality of struts include a series of clot engagement protrusions.

2. The device of claim 1, wherein the plurality of struts form an array of cells in each clot scaffolding section.

3. The device of claim 1, wherein the series of clot engagement protrusions are arranged along at least one proximally facing surface of the at least some of the plurality of struts while at least one other surface of the at least some of the plurality of struts is free from the series of clot engagement protrusions.

4. The device of claim 3, wherein the series of clot engagement protrusions are arranged along a radially inner surface of at least some of the plurality of struts.

5. The device of claim 1, wherein the series of clot engagement protrusions includes one or more of a cylindrical segment, a spherical segment, a conical segment, a frustum, a triangular segment, a D-shaped segment, or an eyelet element.

6. The device of claim 1, further including a distal net included at a distal end of the device selectively moveable relative to the expandable body.

7. The device of claim 1, wherein the series of clot engagement protrusions are disposed on a proximally facing surface of the respective strut whereby the struts are capable of exerting a retracting force on the clot in a direction substantially parallel to a central axis of the blood vessel.

8. The device of claim 1, further including an inner member extending through the expandable body.

9. The device of claim 1, wherein the expandable body is eccentrically coupled to the elongate member.

10. A clot retrieval device for removing clot from a blood vessel, the device having a collapsed delivery configuration and an expanded deployed configuration and comprising:

a shaft extending between a proximal end and a distal end; and

an expandable body eccentrically coupled to and extending distally of the shaft, the expandable body comprising;

at least two clot scaffolding segments connected by a hinge element configured to self-align the clot scaffolding sections for articulating in bends of the vasculature, wherein the hinge element is the only point of contact between the at least two clot scaffolding segments; and

at least one clot inlet mouth between the at least two clot scaffolding segments,

wherein regions of the plurality of at least two clot scaffolding segments are configured to exert an outward radial force on the clot to urge the clot towards the at least one clot inlet mouth; and

wherein the expandable body comprises a plurality of struts and at least some of the plurality of struts include a series of clot engagement protrusions.

11. The device of claim 10, wherein the plurality of struts form an array of cells in each clot scaffolding section.

12. The device of claim 10, wherein the series of clot engagement protrusions are arranged along at least one surface of the at least some of the plurality of struts while at least one other surface of the at least some of the plurality of struts is free from the series of clot engagement protrusions.

13. The device of claim 12, wherein the series of clot engagement protrusions are arranged along a radially inner surface of at least some of the plurality of struts.

14. The device of claim 10, wherein the series of clot engagement protrusions includes one or more of a cylindrical segment, a spherical segment, a conical segment, a frustum, a triangular segment, a D-shaped segment, or an eyelet element.

15. A clot retrieval device for removing clot from a blood vessel, the device having a collapsed delivery configuration and an expanded deployed configuration and comprising:

a shaft extending between a proximal end and a distal end;

an expandable body extending distally of the shaft, the expandable body comprising;

at least two clot scaffolding segments connected by a self-aligning hinge element for articulating bends of the vasculature, wherein the hinge element is the only point of contact between the at least two clot scaffolding segments; and

at least one clot inlet mouth between the at least two clot scaffolding segments,

wherein regions of the plurality of at least two clot scaffolding segments are configured to exert an outward radial force on the clot to urge the clot towards the at least one clot inlet mouth; and

a distal net coupled to the expandable body and extending distally thereof, wherein the expandable body comprises a plurality of struts and at least some of the plurality of struts include a series of clot engagement protrusions disposed on a proximal facing surface of the respective struts.

16. The device of claim 15, wherein the plurality of struts form an array of cells in each clot scaffolding section.

17. The device of claim 15, wherein the series of clot engagement protrusions are arranged along at least one surface of the at least some of the plurality of struts while at least one other surface of the at least some of the plurality of struts is free from the series of clot engagement protrusions.

18. The device of claim 15, wherein the distal net is selectively moveable relative to the expandable body.

19. The device of claim 15, wherein the series of clot engagement protrusions includes one or more of a cylindrical segment, a spherical segment, a conical segment, a frustum, a triangular segment, a D-shaped segment, or an eyelet element.

20. The device of claim 15, further including an inner member extending through the expandable body.