Methods and systems for the treatment of polycystic ovary syndrome

• US 10,595,936 B2
• Filed: 04/21/2017
• Issued: 03/24/2020
• Est. Priority Date: 10/18/2013
• Status: Active Grant

• Current Assignee: May Health US Incorporated
• Original Assignee: Ziva Medical, Inc.
• Inventors: Zarins, Denise, Barman, Neil, Schwab, Garrett, Osborne, Roger, Sutton, Douglas
• Primary Examiner(s): Fowler, Daniel W
• Application Number:
  US15/494,188
• Publication Number:
  US 20170215949A1
• Time in Patent Office: 1,068 Days
• CPC Class Codes: A61B 17/22004 using mechanical vibrations, e.g. ultrasonic shock waves A61B17/225 takes precedence
• CPC Class Codes: A61B 17/42 Gynaecological or obstetrical instruments or methods ligaturing clamps or clips for the umbilical cord A61B17/122; curettage A61B17/320708; dilators A61M29/00
• CPC Class Codes: A61B 18/06 caused by chemical reaction , e.g. moxaburners
• CPC Class Codes: A61B 18/1206 Generators therefor
• CPC Class Codes: A61B 18/1482 having a long rigid shaft for accessing the inner body transcutaneously in minimal invasive surgery, e.g. laparoscopy
• CPC Class Codes: A61B 18/1485 having a short rigid shaft for accessing the inner body through natural openings
• CPC Class Codes: A61B 18/16 Indifferent or passive electrodes for grounding
• CPC Class Codes: A61B 18/22 the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
• CPC Class Codes: A61B 2017/00278 Transorgan operations, e.g. transgastric
• CPC Class Codes: A61B 2017/003 Steerable
• CPC Class Codes: A61B 2017/00455 Orientation indicators, e.g. recess on the handle
• CPC Class Codes: A61B 2017/306 holding by means of suction
• CPC Class Codes: A61B 2017/3405 using mechanical guide means
• CPC Class Codes: A61B 2017/3413 guided by ultrasound
• CPC Class Codes: A61B 2017/3488 Fixation to inner organ or inner body tissue
• CPC Class Codes: A61B 2017/4233 Operations on Fallopian tubes, e.g. sterilization A61B2017/1125 takes precedence
• CPC Class Codes: A61B 2018/00196 reciprocating lengthwise
• CPC Class Codes: A61B 2018/00273 Anchoring means for temporary attachment of a device to tissue
• CPC Class Codes: A61B 2018/00285 Balloons
• CPC Class Codes: A61B 2018/00291 using suction
• CPC Class Codes: A61B 2018/00559 : Female reproductive organs
• CPC Class Codes: A61B 2018/00577 : Ablation
• CPC Class Codes: A61B 2018/00589 : Coagulation
• CPC Class Codes: A61B 2018/00595 : Cauterization
• CPC Class Codes: A61B 2018/00642 : with feedback, i.e. closed loop control
• CPC Class Codes: A61B 2018/00702 : Power or energy
• CPC Class Codes: A61B 2018/0072 : Current
• CPC Class Codes: A61B 2018/00726 : Duty cycle
• CPC Class Codes: A61B 2018/00732 : Frequency
• CPC Class Codes: A61B 2018/00744 : Fluid flow
• CPC Class Codes: A61B 2018/00767 : Voltage
• CPC Class Codes: A61B 2018/00791 : Temperature
• CPC Class Codes: A61B 2018/00875 : Resistance or impedance
• CPC Class Codes: A61B 2018/00982 : combined with or comprising means for visual or photographic inspections inside the body, e.g. endoscopes
• CPC Class Codes: A61B 2018/0293 : using an instrument interstitially inserted into the body, e.g. needle
• CPC Class Codes: A61B 2018/048 : in gaseous form
• CPC Class Codes: A61B 2018/143 : multiple needles
• CPC Class Codes: A61B 2018/1432 : curved
• CPC Class Codes: A61B 2018/1475 : Electrodes retractable in or deployable from a housing
• CPC Class Codes: A61B 2090/378 : using ultrasound
• CPC Class Codes: A61B 2090/3925 : ultrasonic
• CPC Class Codes: A61B 2090/3966 : Radiopaque markers visible in an X-ray image
• CPC Class Codes: A61B 8/0841 : for locating instruments
• CPC Class Codes: A61B 8/085 : for locating body or organic structures, e.g. tumours, calculi, blood vessels, nodules
• CPC Class Codes: A61B 8/12 : in body cavities or body tracts, e.g. by using catheters catheters per se A61M25/00
• CPC Class Codes: A61B 8/4427 : Device being portable or laptop-like
• CPC Class Codes: A61B 8/4433 : involving a docking unit
• CPC Class Codes: A61F 6/20 : Vas deferens occluders; Fallopian occluders
• CPC Class Codes: A61N 2007/0043 : intra-cavitary
• CPC Class Codes: A61N 7/02 : Localised ultrasound hyperthermia hyperthermia in general A61F7/00
• CPC Class Codes: A61N 7/022 : intracavitary

Abstract

Described here are methods and systems for the manipulation of ovarian tissues. The methods and systems may be used in the treatment of polycystic ovary syndrome (PCOS). The systems and methods may be useful in the treatment of infertility associated with PCOS.

Claims

1. A system for performing an ovarian procedure in combination with a transvaginal probe having a probe handle, the system comprising:

a docking device comprising a proximal end, a distal end, and an elongate body having a lumen, the docking device further comprising;

an alignment element disposed at the proximal end proximal to the elongate body;

a docking device handle comprising a deployment feature; and

a radiofrequency energy element slidable within and deployable from the lumen of the docking device upon manipulation of the deployment feature, and comprising a curved distal portion;

an adapter configured to be removably coupled to the probe handle, the adapter comprising a receiving alignment channel having a geometry that allows engagement with the alignment element in a manner that maintains planar orientation and limits rotation of the docking device and radiofrequency energy element relative to the transvaginal probe; and

a generator configured to supply radiofrequency energy to the radiofrequency energy element.

2. The system of claim 1, wherein the radiofrequency energy element comprises an elongate body having a straightened length, a radius of curvature for the curved distal portion, an active electrode, and a return electrode.

3. The system of claim 2, wherein the straightened length ranges between about 5.0 and about 40 mm.

4. The system of claim 2, wherein the radius of curvature ranges between about 3.0 and about 10 mm.

5. The system of claim 1, wherein the docking device handle is configured to limit distal movement of the docking device relative to the transvaginal probe.

6. The system of claim 1, wherein the generator is configured to supply radiofrequency energy at a power of about 15 watts, and for a duration of about 20 to 60 seconds.

7. The system of claim 1, wherein the radiofrequency energy element comprises an echogenic material.

8. The system of claim 1, wherein a portion of the docking device comprises an echogenic material.

9. The system of claim 1, wherein the radiofrequency energy element and the docking device comprise an echogenic material having different echogenicity.

10. The system of claim 1, wherein the radiofrequency energy element comprises a plurality of areas of echogenic material having different echogenicity.