Devices and methods for non-invasive multi-wavelength photobiomodulation for ocular treatments
First Claim
1. A device for delivery of photobiomodulation (PBM) to retinal tissue of an eye of a patient, the device comprising:
- a housing comprising an interior;
an eyepiece or eyebox configured and arranged for placement of at least one eye of the patient adjacent the eyepiece or eyebox;
a first light source selected from one or more LED, lamp, or laser, or any combination thereof, wherein the first light source is configured to produce a first light beam having a first therapeutic wavelength, and wherein the first light source is disposed within the housing;
a second light source selected from one or more LED, lamp, or laser, or any combination thereof, wherein the second light source is configured to produce a second light beam having a second therapeutic wavelength, wherein the second light source is disposed within the housing, and wherein the second therapeutic wavelength differs from the first therapeutic wavelength by at least 25 nm;
a relay structure configured and arranged to receive the first light beam and the second light beam from the first light source and the second light source, respectively, and to direct the first light beam and the second light beam to the eyepiece or eyebox; and
an actuator configured and arranged to move at least a portion of the relay structure to change a direction of at least one of the first light beam and the second light beam from at least a first position to at least a second position.
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Accused Products
Abstract
An ophthalmic phototherapy device and associated treatment methods to expose an eye to selected multi-wavelengths of light to promote the healing of damaged or diseased eye tissue. The device includes a housing having an interior; an eyepiece disposed on the housing and configured and arranged for placement of an eye of the patient adjacent the eyepiece; a first light source producing a first light beam having a first therapeutic wavelength and disposed within the housing; a second light source producing a second light beam having a second therapeutic wavelength and disposed within the housing, where the second therapeutic wavelength differs from the first therapeutic wavelength by at least 25 nm.
109 Citations
23 Claims
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1. A device for delivery of photobiomodulation (PBM) to retinal tissue of an eye of a patient, the device comprising:
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a housing comprising an interior; an eyepiece or eyebox configured and arranged for placement of at least one eye of the patient adjacent the eyepiece or eyebox; a first light source selected from one or more LED, lamp, or laser, or any combination thereof, wherein the first light source is configured to produce a first light beam having a first therapeutic wavelength, and wherein the first light source is disposed within the housing; a second light source selected from one or more LED, lamp, or laser, or any combination thereof, wherein the second light source is configured to produce a second light beam having a second therapeutic wavelength, wherein the second light source is disposed within the housing, and wherein the second therapeutic wavelength differs from the first therapeutic wavelength by at least 25 nm; a relay structure configured and arranged to receive the first light beam and the second light beam from the first light source and the second light source, respectively, and to direct the first light beam and the second light beam to the eyepiece or eyebox; and an actuator configured and arranged to move at least a portion of the relay structure to change a direction of at least one of the first light beam and the second light beam from at least a first position to at least a second position. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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14. A device for delivery of photobiomodulation (PBM) to retinal tissue of an eye of a patient, the device comprising:
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a housing comprising an interior; an eyepiece or eyebox configured and arranged for placement of at least one eye of the patient adjacent the eyepiece or eyebox; a first light source selected from one or more LED, lamp, or laser, or any combination thereof, wherein the first light source is configured to produce a first light beam having a first therapeutic wavelength, and wherein the first light source is disposed within the housing; a second light source selected from one or more LED, lamp, or laser, or any combination thereof, wherein the second light source is configured to produce a second light beam having a second therapeutic wavelength, wherein the second therapeutic wavelength differs from the first therapeutic wavelength by at least 25 nm; a reflective filter disposed within the housing and configured and arranged to substantially pass light having the first therapeutic wavelength and substantially reflect light having the second therapeutic wavelength, wherein the device is configured and arranged to direct the first and second light beams to the reflective filter and through the eyepiece or eyebox to provide PBM to the retinal tissue of the patient; a relay structure configured and arranged to receive the first light beam and the second light beam and direct the first light beam and the second light beam to the eyepiece or eyebox; and an actuator configured and arranged to move at least a portion of the relay structure to change a direction of at least one of the first light beam and the second light beam from at least a first position to at least a second position. - View Dependent Claims (15, 16, 17, 18, 19, 20, 21, 22)
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23. A device for delivery of photobiomodulation (PBM) to retinal tissue of an eye of a patient, the device comprising:
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a housing comprising an interior; an eyepiece or eyebox configured and arranged for placement of at least one eye of the patient adjacent the eyepiece or eyebox; a first light source selected from one or more LED, lamp, or laser, or any combination thereof, wherein the first light source is configured to produce a first light beam having a first therapeutic wavelength, and wherein the first light source is disposed within the housing; a second light source selected from one or more LED, lamp, or laser, or any combination thereof, wherein the second light source is configured to produce a second light beam having a second therapeutic wavelength, wherein the second light source is separate from the first light source and is disposed within the housing, and wherein the second therapeutic wavelength differs from the first therapeutic wavelength by at least 25 nm; a programmable controller operatively coupled to the first light source and to the second light source, wherein the programmable controller is configured, for each of the first light beam and the second light beam, to control one or more PBM parameter selected from a light energy emission, a light energy density, a light energy duration, a light energy frequency, a light energy area, or a light energy sequence, or any combination thereof; a relay structure configured and arranged to receive the first light beam and the second light beam and direct the first light beam and the second light beam to the eyepiece or eyebox; and an actuator configured and arranged to move at least a portion of the relay structure to change a direction of at least one of the first light beam and the second light beam from a first position to a second position.
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Specification