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Dimethyl sulfoxide (DMSO) or DMSO and methylsulfonylmethane (MSM) formulations to treat infectious diseases

  • US 10,596,109 B2
  • Filed: 12/01/2017
  • Issued: 03/24/2020
  • Est. Priority Date: 10/30/2009
  • Status: Active Grant
First Claim
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1. A system for treating drug-resistant tuberculosis, comprising:

  • a pretreatment composition configured for intravenous administration, the pretreatment composition comprising about 50 mg to about 60 mg dimethylsulfoxide (DMSO);

    a formulation comprising therapeutic agents dissolved in DMSO,wherein a concentration of the DMSO ranges from about 50% to about 95% in a total volume of about two to about six milliliters of the formulation,wherein the therapeutic agents are selected from three or more compounds selected from the group consisting of;

    streptomycin, isoniazid, rifampicin, pyraziamide, and ethambutol; and

    an inhalant device.

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