Guide wires, catheters, and guide wire catheter systems and methods

• US 10,596,354 B2
• Filed: 09/23/2016
• Issued: 03/24/2020
• Est. Priority Date: 09/25/2015
• Status: Active Grant

• Current Assignee: Mark Taber
• Original Assignee: Mark Taber
• Inventors: Taber, Mark
• Primary Examiner(s): Dougherty, Sean P
• Assistant Examiner(s): Melhus, Benjamin S
• Application Number:
  US15/274,701
• Publication Number:
  US 20170087339A1
• Time in Patent Office: 1,278 Days
• CPC Class Codes: A61M 2025/09125 Device for locking a guide wire in a fixed position with respect to the catheter or the human body
• CPC Class Codes: A61M 2025/09133 having specific material compositions or coatings; Materials with specific mechanical behaviours, e.g. stiffness, strength to transmit torque
• CPC Class Codes: A61M 2025/09166 having radio-opaque features
• CPC Class Codes: A61M 2025/09175 having specific characteristics at the distal tip
• CPC Class Codes: A61M 25/09041 Mechanisms for insertion of guide wires
• CPC Class Codes: A61M 25/0905 extendable, e.g. mechanisms for extension
• CPC Class Codes: A61M 25/10 Balloon catheters A61M25/0125 takes precedence; embolectomy A61B17/22032; retractors A61B17/02; inflatable balloons for placing stents or stent-grafts A61F2/958 ; stomach balloons for treatment of obesity A61F5/0003; oesophagal tubes A61J15/00

Abstract

Guide wires, systems and methods can improve advancement through the vasculature, particularly when the catheter tip encounters resistance or an obstruction and cannot advance. The guide wire can include an enlargement spaced proximally from a distal tip of the elongated member alone or in combination with a configured portion of the wire. The configured guide wire can be positioned in the vasculature and a medical device such as a catheter can track over the guide wire. The catheter can get caught-up in the vasculature or on implanted devices during advancement. When that occurs, the configured guide wire can be retracted back to the catheter tip and the guide wire configuration can cause the catheter distal tip to move and/or deflect away from the obstruction or resistance allowing the system to advance. The guide wire can be returned to its distal position and the procedure can continue.

Claims

1. A system comprising:

a catheter having a catheter tip, a proximal portion, and a distal portion;

a guide wire configured for advancing a device having a longitudinal lumen diameter through a vasculature, the guide wire comprising;

an elongated member having a proximal end and a distal end; and

an enlargement being disposed on the distal end of the elongated member, the enlargement being spaced proximally from a distal tip of the distal end of the elongated member, the enlargement having a dimension larger than the distal tip and the longitudinal lumen diameter of the device,

wherein an outer diameter of the enlargement is configured to be greater than an outer diameter of the catheter tip, the enlargement enlarges radially from the catheter tip along a longitudinal axis of the enlargement, and

wherein the enlargement is adapted to move the device away from an obstruction or the vasculature.

2. The system of claim 1, wherein a portion of the proximal end of the elongated member has a rigidity coefficient greater than a portion of the distal end.

3. The system of claim 1, further comprising a bend in the elongated member, the bend being disposed proximate the enlargement on a proximal side of the enlargement.

4. The system of claim 3, wherein at least one of the bend and the enlargement has a hydrophilic coating or is radio-opaque.

5. The system of claim 3, wherein the bend is at least one of:

a curve, a sinusoidal curve, a non-linear section, an angulation, a peak, a valley, a squiggle, curvilinear, and helical.

6. The system of claim 3, wherein the bend has a variable stiffness.

7. The system of claim 3, wherein the bend has a stiffness coefficient greater than the remaining portion of the elongated member.

8. The system of claim 1, wherein the enlargement has a profile that is determined based upon a catheter tip profile and the enlargement is greater than the catheter tip profile.

9. The system of claim 8, wherein the enlargement profile is about 30 percent larger than the catheter tip profile.

10. The system of claim 8, wherein a diameter of the guide wire is 0.014 inches and a diameter of the enlargement is 0.027 inches, when used with a 0.021 inch diameter catheter tip.

11. The system of claim 1, the guide wire further comprising linearly spaced radio-opaque markers to facilitate measurement of a lesion length.

12. The system of claim 1, wherein the enlargement has a radial dimension that is determined based upon the catheter tip outer diameter.

13. The system of claim 1, wherein the enlargement is spherical shaped.

14. The system of claim 1, wherein the enlargement is non-spherical shaped.

15. The system of claim 1, wherein the catheter has a catheter shaft and is configured to encompass the guide wire.

16. The system of claim 15, wherein the guide wire comprises linearly spaced radio-opaque markers to facilitate measurement of a lesion length.

17. The system of claim 15, wherein the enlargement is proximally offset from a distal tip of the distal end of the guide wire.

18. The system of claim 15, wherein the distal portion is enlarged in relation to the catheter shaft, the catheter tip being configured to engage with the enlargement of the guide wire upon the catheter becoming stuck.

19. The system of claim 18, wherein the outer diameter of the catheter tip is 30% greater than an outer diameter of the shaft of the catheter.

20. The system of claim 15, wherein the catheter includes a balloon that protrudes radially from, and extends along, the shaft of the catheter.

21. The system of claim 15, wherein the guide wire has a non-linear portion of at least one of:

a curve, a sinusoidal curve, a non-linear section, an angulation, a peak, a valley, a squiggle, curvilinear, and helical.

22. The system of claim 1, wherein the elongated member has a uniform outer diameter and wherein the distal tip of the distal end of the elongated member has a same or smaller outer diameter as the uniform outer diameter of the elongated member.

23. The system of claim 1, further comprising a bend in the elongated member, the bend being disposed proximate the enlargement, wherein the bend is adapted to deflect the device away from the obstruction or the vasculature.

24. The system of claim 23, wherein the bend is disposed at least one of proximal the enlargement, distal to the enlargement, or at the enlargement.

25. The system of claim 1, wherein the enlargement has a profile that is determined based upon a catheter tip profile and the enlargement is greater than the catheter tip profile, and wherein the enlargement is adapted to move the catheter tip away from the obstruction or the vasculature.

26. The system of claim 1, wherein the enlargement shrinks radially at a distance spaced from the catheter tip.

27. The system of claim 1, the enlargement further comprising a proximal end having a first dimension and a distal end having a second dimension, wherein a third dimension located between the proximal end and the distal end is larger than at least one of the first dimension and the second dimension.

28. The system of claim 1, the elongated member further comprising a non-linear portion adjacent the enlargement.

29. The system of claim 1, wherein the enlargement is configured to partially retreat inside the catheter tip.

30. The system of claim 1, wherein the enlargement is configured to not retreat inside the catheter tip.

31. The system of claim 1, wherein the enlargement further comprises multiple enlargements, and wherein the guide wire further comprises a non-linear portion, the multiple enlargements disposed at the non-linear portion.

32. The system of claim 1, wherein the enlargement further comprises multiple enlargements.

33. The system of claim 32, wherein the guide wire further comprises a non-linear portion, wherein at least one of the multiple enlargements is disposed at the non-linear portion.

34. The system of claim 33, wherein at least one of the multiple enlargements is disposed proximate the non-linear portion.

35. The system of claim 1, wherein the enlargement comprises a distal enlargement spaced apart from a proximal enlargement and the proximal enlargement has an outer diameter that is equal to or smaller than the distal enlargement.

36. The system of claim 1, wherein the enlargement comprises a distal enlargement spaced apart from a proximal enlargement and the distal enlargement has an outer diameter that is equal to or smaller than the proximal enlargement.

37. A method of navigating through vasculature, comprising:

advancing a guide wire through a vessel, the guide wire having a substantially uniform outer diameter, and the guide wire having a distal portion that includes a radial bulge;

advancing a catheter over the guide wire, the catheter having a proximal end and a distal end, wherein the radial bulge is larger than the distal end of the catheter;

encountering a vascular obstruction hindering advancement of the catheter; and

withdrawing the guide wire through the catheter to position the radial bulge in contact with the distal end of the catheter,

wherein the step of withdrawing allows the distal end of the catheter to be displaced away from the vascular obstruction to allow advancement of the catheter.

38. The method of claim 37, further comprising the step of:

advancing the catheter in contact with the radial bulge together past the vascular obstruction based on the guide wire displacing the distal end of the catheter.

39. The method of claim 37, further comprising the step of:

advancing the guide wire and the catheter separately past the vascular obstruction.

40. The method of claim 37, further comprising the step of:

maintaining the distal end of the catheter at the vascular obstruction while the guide wire is withdrawn and until the radial bulge is in contact with the distal end of the catheter.

41. The method of claim 37, where the step of withdrawing further comprises withdrawing the radial bulge causing the distal end of the catheter to become unobstructed.

42. The method of claim 37, wherein the step of advancing a guide wire further comprises advancing the guide wire with a curve proximate and proximal to the radial bulge.

43. The method of claim 37, further comprising rotating the guide wire upon encountering the vascular obstruction to assist in passage past or penetration through the vascular obstruction of the guide wire and catheter.

44. The method of claim 37, wherein the radial bulge comprises a proximal radial bulge and a distal radial bulge spaced apart from the radial bulge.

45. The method of claim 44, wherein withdrawing the guide wire through the catheter to position the radial bulge in contact with the distal end of the catheter further comprises withdrawing the proximal radial bulge within the catheter and withdrawing the distal radial bulge in contact with the distal end of the catheter, wherein the distal radial bulge interfaces with the vascular obstruction.

46. A guide wire configured for advancing a device having a longitudinal lumen diameter through a vasculature, the guide wire comprising:

an elongated member having a proximal end and a distal end;

an enlargement being disposed on the distal end of the elongated member, the enlargement being spaced proximally from a distal tip of the distal end of the elongated member, the enlargement having a dimension larger than the distal tip and the longitudinal lumen diameter of the device; and

a sinusoidal curve disposed proximate the enlargement on a proximal side of the enlargement,

wherein an outer diameter of the enlargement is configured to be greater than an outer diameter of a catheter tip, the enlargement enlarges radially from the catheter tip,

wherein the enlargement is adapted to move the device away from an obstruction or the vasculature.

47. The guide wire of claim 46, wherein the enlargement further comprises multiple enlargements.

48. The guide wire of claim 47, wherein at least one of the multiple enlargements is disposed at the sinusoidal curve.