Endovascular cerebrospinal fluid shunt

• US 10,596,357 B2
• Filed: 04/06/2017
• Issued: 03/24/2020
• Est. Priority Date: 01/15/2014
• Status: Active Grant

• Current Assignee: Tufts Medical Center Incorporated (Healthcare Realty Trust, Inc.)
• Original Assignee: Tufts Medical Center Incorporated (Healthcare Realty Trust, Inc.)
• Inventors: Heilman, Carl, Malek, Adel M.
• Primary Examiner(s): Marcetich, Adam
• Application Number:
  US15/480,543
• Publication Number:
  US 20170209676A1
• Time in Patent Office: 1,083 Days
• CPC Class Codes: A61B 17/12168 having a mesh structure A61B17/1214 takes precedence
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 2090/3966 Radiopaque markers visible in an X-ray image
• CPC Class Codes: A61B 90/39 Markers, e.g. radio-opaque or breast lesions markers
• CPC Class Codes: A61M 2210/0693 Brain, cerebrum
• CPC Class Codes: A61M 2210/12 Blood circulatory system
• CPC Class Codes: A61M 27/006 Cerebrospinal drainage; Accessories therefor, e.g. valves

Abstract

Implantable shunt devices and methods for draining cerebrospinal fluid from a patient'"'"'s subarachnoid space include a shunt having opposed first and second ends, the second end being constructed to penetrate a wall of a sigmoid, transverse, straight, or sagittal sinus of the patient, a one-way valve, a hollow passageway extending between the second end and the one-way valve such that cerebrospinal fluid can be drained through the second end and out through the valve, and a mechanism coupled to the shunt and configured to anchor the shunt at a desired location proximal to the subarachnoid space.

Claims

1. A method for draining cerebrospinal fluid from a patient'"'"'s subarachnoid space into the venous system, the method comprising:

providing a shunt having opposed first and second ends and a one-way valve, wherein the first and second ends are in fluid communication to enable the cerebrospinal fluid to be drained from the subarachnoid space through the second end, the first end and the valve into the venous system;

endovascularly delivering the shunt to a dural venous sinus;

stabilizing the shunt against an inner wall of the dural venous sinus at a desired location proximal to the subarachnoid space;

implanting a portion of the shunt through the venous sinus wall of the patient; and

draining cerebrospinal fluid from the patient'"'"'s subarachnoid space into the patient'"'"'s venous system.

2. The method of claim 1, wherein endovascularly delivering the shunt to the dural venous sinus includes using a catheter.

3. The method of claim 1, further comprising:

placing the shunt percutaneously into the venous system of the patient without the need for open surgery.

4. The method of claim 1, further comprising draining the cerebrospinal fluid into a venous sinus lumen of the patient.

5. The method of claim 1, further comprising positioning a projection between said first and second ends of the shunt.

6. The method of claim 5, further comprising:

abutting the projection against the sinus wall.

7. The method of claim 1, further comprising providing the shunt including a tip with a sharpened end disposed at the second end of the shunt.

8. The method of claim 7, further comprising:

penetrating the sinus wall of the patient with the sharpened end.

9. The method of claim 1, further comprising providing the shunt with a tip at the second end of the shunt.

10. The method of claim 9, wherein the tip is a helical tip.

11. The method of claim 1 further comprising shielding the shunt in the subarachnoid space from surrounding brain parenchyma tissue.

12. The method of claim 11 further comprising providing the shunt with a globe-shaped member.

13. The method of claim 12 wherein the globe-shaped member is configured to revert to an initial globe shape upon being positioned within the subarachnoid space.

14. The method of claim 1 further comprising providing the shunt with a radiopaque material.

15. The method of claim 1 further comprising stabilizing the shunt with an inflatable balloon.

16. The method of claim 1 further comprising stabilizing the shunt with a collapsible member.

17. The method of claim 1 further comprising providing a stabilizing member configured to apply a constant outward radial force and anchor the shunt against the inner wall of the dural venous sinus at the desired location proximal to the subarachnoid space.

18. The method of claim 1 further comprising draining 10 cubic centimeters of CSF per hour.

19. The method of claim 1 wherein endovascularly delivering the shunt includes accessing the sinus wall via a femoral vein or a jugular vein.

20. The method of claim 1 further comprising preventing sinus blood from flowing into the subarachnoid space.

21. The method of claim 1 wherein the one-way valve is located at the first end or second end of the shunt.

22. The method of claim 1 wherein the one-way valve is located between the first end and second end of the shunt.