Solid-forming local anesthetic formulations for pain control
First Claim
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1. A formulation for pain control, comprising:
- from about 4 wt % to about 10 wt % lidocaine;
from about 4 wt % to about 10 wt % tetracaine;
from about 10 wt % to about 18 wt % polyvinyl alcohol;
from about 2 wt % to about 6 wt % of an emulsifier selected from sorbitan monopalmitate or sorbitan monostearate;
from about 25.94 wt % to about 51.87 wt % water;
from about 2 wt % to about 13 wt % petrolatum; and
from about 18 wt % to about 36 wt % dicalcium phosphate;
wherein the formulation has an initial viscosity that ranges from about 40,000 centipoise to 370,500 centipoise.
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Abstract
Solid-forming local anesthetic formulations for pain control can include a lidocaine base and tetracaine base, polyvinyl alcohol, water, and an emulsifier. The formulation can be prepared to be in a semi-solid state prior to application to a skin surface, can form a soft solidified layer after application, and can provide pain relief when applied to a skin surface proximate a pain site.
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Citations
14 Claims
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1. A formulation for pain control, comprising:
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from about 4 wt % to about 10 wt % lidocaine; from about 4 wt % to about 10 wt % tetracaine; from about 10 wt % to about 18 wt % polyvinyl alcohol; from about 2 wt % to about 6 wt % of an emulsifier selected from sorbitan monopalmitate or sorbitan monostearate; from about 25.94 wt % to about 51.87 wt % water; from about 2 wt % to about 13 wt % petrolatum; and from about 18 wt % to about 36 wt % dicalcium phosphate; wherein the formulation has an initial viscosity that ranges from about 40,000 centipoise to 370,500 centipoise. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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Specification