Band transducer ultrasound therapy

• US 10,603,521 B2
• Filed: 12/27/2017
• Issued: 03/31/2020
• Est. Priority Date: 04/18/2014
• Status: Active Grant

• Current Assignee: Ulthera Inc. (Merz Pharma GmbH & Company Kgaa)
• Original Assignee: Ulthera Inc. (Merz Pharma GmbH & Company Kgaa)
• Inventors: Emery, Charles D., Peterson, Michael T., Hope, Joshua D.
• Primary Examiner(s): Pehlke, Carolyn A
• Application Number:
  US15/855,949
• Publication Number:
  US 20180117366A1
• Time in Patent Office: 825 Days
• CPC Class Codes: A61B 2017/00084 Temperature
• CPC Class Codes: A61B 2017/00106 ultrasonic
• CPC Class Codes: A61N 2007/0034 Skin treatment
• CPC Class Codes: A61N 2007/0065 Concave transducers
• CPC Class Codes: A61N 2007/0078 with multiple treatment transducers
• CPC Class Codes: A61N 2007/0082 Scanning transducers
• CPC Class Codes: A61N 2007/0091 with moving parts, e.g. transducers, lenses, reflectors
• CPC Class Codes: A61N 7/02 Localised ultrasound hyperthermia hyperthermia in general A61F7/00
• CPC Class Codes: G10K 11/30 using refraction, e.g. acoustic lenses
• CPC Class Codes: G10K 11/352 by moving the transducer

Abstract

Embodiments of a dermatological cosmetic treatment and/or imaging system and method can include use of transducer to create a linear thermal treatment zone at a focal depth to form a band shaped treatment area. The system can include one or more ultrasound transducers, a cylindrical transduction element, an imaging element, a hand wand, a removable transducer module, a control module, and/or graphical user interface. In some embodiments, a coated transducer may be used to provide more consistent treatment in cosmetic procedures, including brow lifts, fat reduction, sweat reduction, and treatment of the décolletage. Skin tightening, lifting and amelioration of wrinkles and stretch marks are provided. Treatment may include heating of tissue for a duration to deactivate a percentage of cells in the treatment region.

Claims

1. A method of reducing variance in focal gain in a planar band treatment area for heating tissue with a cylindrically focused ultrasound transducer, comprising:

applying a current from a power source to a cylindrical transduction element to form a linear focal zone at a focal depth,

moving the cylindrical transduction element with a motion mechanism along a linear path perpendicular to the linear focal zone to produce a planar band treatment area, and

reducing a variance in focal gain at the linear focal zone at the focal depth by applying an electrical signal to a portion of the cylindrical transduction element, the cylindrical transduction element comprising a first surface, a second surface, a plurality of coated regions, and an uncoated region,

wherein the plurality of coated regions comprises an electrical conductor,

wherein the first surface comprises at least one coated region of the plurality of the coated regions,

wherein the second surface comprises the uncoated region and a subset of the plurality of coated regions,

wherein the subset of the plurality of coated regions on the second surface cover at least 60% of the second surface,

wherein the subset of the plurality of coated regions on the second surface comprise a lateral edge, a medial edge, a first side edge, and a second side edge, and the portion of the cylindrical transduction element comprises the subset of the plurality of coated regions,

wherein the applying the signal to the subset of the plurality of coated regions directs uniform ultrasound energy with a reduced focal gain to the linear focal zone at the focal depth.

2. The method of claim 1, wherein the reducing the focal gain facilitates the efficient and consistent treatment of tissue, wherein the cylindrical transduction element applies ultrasonic therapy to a thermal treatment zone at the focal depth.

3. The method of claim 1, wherein the reducing the focal gain reduces a peak such that a variance around the focal depth is reduced by 75-200%.

4. The method of claim 1, wherein the reducing the focal gain reduces a peak such that a variance of an intensity around the focal depth is 5 mm or less.

5. The method of claim 1, wherein the reducing the focal gain reduces a variance in focal gain in a range of 0.01-10.

6. The method according to claim 1, wherein the cylindrical transduction element is housed within an ultrasonic hand-held probe, wherein the ultrasonic probe comprises:

a housing,

the cylindrical transduction element, and

the motion mechanism;

wherein the ultrasound transducer is movable within the housing,

wherein the motion mechanism is attached to the ultrasound transducer, and further comprising stopping the ultrasound transducer along the linear path within the housing.

7. A method of reducing variance in focal gain in a planar band treatment area for heating tissue with a cylindrically focused ultrasound transducer, comprising:

using a cylindrical transduction element to reduce edge noise at a linear focal zone at a focal depth by reducing a variance in a focal gain in a range of 0.01-10 by driving the cylindrical transduction element with a power source for applying ultrasonic energy to the linear focal zone at the focal depth,

wherein the driving the cylindrical transduction element comprises applying an electric signal from the power source to a plurality of electrically conductive coated regions on the cylindrical transduction element, and

moving the cylindrical transduction element with a motion mechanism along a linear path perpendicular to the linear focal zone to produce a uniform, planar heating area.

8. The method of claim 7,

wherein the cylindrical transduction element comprises a first surface and a second surface,

wherein the first surface comprises an electrically conductive coating fully covering the first surface,

wherein the second surface comprises two electrically conductive coated regions and at least one region that is not coated with an electrically conductive coating,

wherein the two coated regions on the second surface comprises a conductive material that forms an electrode when the power source is in electric communication with each coated region,

wherein the conductive material comprises silver;

wherein the coated regions on the second surface cover at least 80% of the second surface;

wherein the coated regions on the second surface comprise a lateral edge, a medial edge, a first side edge, and a second side edge,

wherein the driving the cylindrical transduction element comprises applying an electric signal from the power source to the coated regions on the second surface.

9. The method of claim 7, wherein the first surface is a concave surface and the second surface is a convex surface.

10. The method of claim 7, wherein the cylindrical transduction element is housed within an ultrasonic hand-held probe, wherein the ultrasonic probe comprises:

a housing,

the cylindrical transduction element, and

a motion mechanism;

wherein the ultrasound transducer is movable within the housing,

wherein the motion mechanism is attached to the ultrasound transducer, and further comprising moving the ultrasound transducer along a linear path within the housing.

11. The method of claim 10, further comprising moving the cylindrical transduction element with the motion mechanism to heat a treatment area at the focal depth to a temperature in a range between 40-65 degrees Celsius.

12. The method of claim 7, further comprising producing a uniform temperature in a treatment area with the cylindrical transduction element in a range of 42-55 degrees Celsius in the material at the focal depth.

13. The method of claim 7, further comprising imaging the material with one or more imaging elements, wherein the cylindrical transduction element further comprises an opening for placement of the one or more imaging elements.

14. A method of reducing variance in focal gain in a planar band treatment area for heating tissue with a cylindrically focused ultrasound transducer, comprising:

using a cylindrical transduction element to reduce edge noise at a linear focal zone at a focal depth with the cylindrical transduction element by reducing a variance of an intensity around the focal depth to 5 mm or less by driving the cylindrical transduction element with a power source for applying ultrasonic energy to the linear focal zone at the focal depth,

wherein the driving the cylindrical transduction element comprises applying an electric signal from the power source to a plurality of coated regions on the cylindrical transduction element, and

moving the cylindrical transduction element with a motion mechanism along a linear path perpendicular to the linear focal zone to produce a uniform, planar heating area.

15. The method of claim 14,

wherein the cylindrical transduction element comprises a first surface and a second surface,

wherein the first surface comprises an electrically conductive coating,

wherein the second surface comprises at least two electrically conductive coated regions and at least one region that is not coated with an electrically conductive coating,

wherein the at least two coated regions on the second surface comprises a conductive material that forms an electrode when the power source is in electric communication with the at least two coated regions,

wherein the conductive material comprises any one or more of the group consisting of:

silver, copper, gold, and chrome;

wherein the coated regions on the second surface comprise curved edges and straight edges;

wherein the coated regions on the second surface cover at least 70% of the second surface,

wherein the driving the cylindrical transduction element comprises applying an electric signal from the power source to the at least two electrically conductive coated regions on the second surface.

16. The method of claim 14, wherein the cylindrical transduction element is housed within an ultrasonic hand-held probe, wherein the ultrasonic probe comprises:

a housing,

the cylindrical transduction element, and

a motion mechanism;

wherein the ultrasound transducer is movable within the housing,

wherein the motion mechanism is attached to the ultrasound transducer, and further comprising moving the ultrasound transducer along a linear path within the housing.

17. The method of claim 14, further comprising moving the cylindrical transduction element with the motion mechanism to heat a treatment area at the focal depth to a temperature in a range between 40-65 degrees Celsius.

18. The method of claim 14, wherein the reducing edge noise facilitates the production of a uniform temperature in a treatment area.

19. The method of claim 14, wherein the power source drives the cylindrical transduction element to produce a temperature in a range of 42-55 degrees Celsius in a tissue at the focal depth.

20. The method of claim 14, further comprising one or more imaging elements, wherein the cylindrical transduction element has an opening for placement of the one or more imaging elements.