Systems and methods using a gas mixture to select ions
First Claim
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1. A system configured to permit switching of a cell between at least two modes comprising a collision mode and a reaction mode to select ions received by the cell, the system comprising:
- a cell configured to receive a gas mixture comprising a binary gas mixture in the collision mode to pressurize the cell and configured to receive the same gas mixture comprising the binary gas mixture in the reaction mode to pressurize the cell; and
a processor electrically coupled to the cell, the processor configured to provide a voltage to the pressurized cell comprising the gas mixture in the collision mode to facilitate the transmission of select ions with an energy greater than an energy barrier induced by the provided first voltage, wherein the processor is further configured to provide a second voltage to the pressurized cell comprising the gas mixture in the reaction mode to guide select ions into a mass filter fluidically coupled to the cell.
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Abstract
Certain configurations described herein are directed to mass spectrometer systems that can use a gas mixture to select and/or detect ions. In some instances, the gas mixture can be used in both a collision mode and in a reaction mode to provide improved detection limits using the same gas mixture.
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Citations
20 Claims
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1. A system configured to permit switching of a cell between at least two modes comprising a collision mode and a reaction mode to select ions received by the cell, the system comprising:
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a cell configured to receive a gas mixture comprising a binary gas mixture in the collision mode to pressurize the cell and configured to receive the same gas mixture comprising the binary gas mixture in the reaction mode to pressurize the cell; and a processor electrically coupled to the cell, the processor configured to provide a voltage to the pressurized cell comprising the gas mixture in the collision mode to facilitate the transmission of select ions with an energy greater than an energy barrier induced by the provided first voltage, wherein the processor is further configured to provide a second voltage to the pressurized cell comprising the gas mixture in the reaction mode to guide select ions into a mass filter fluidically coupled to the cell. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
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Specification