Method for testing insurgence of spinal ischemia due to endovascular treatment of aortic aneurisms

• US 10,617,424 B2
• Filed: 07/21/2017
• Issued: 04/14/2020
• Est. Priority Date: 05/10/2011
• Status: Active Grant

• Current Assignee: Be Safe SRL
• Original Assignee: Be Safe SRL
• Inventors: Zanatta, Paolo, Farneti, Fabrizio
• Primary Examiner(s): McEvoy, Thomas M
• Application Number:
  US15/656,984
• Publication Number:
  US 20170319215A1
• Time in Patent Office: 998 Days
• CPC Class Codes: A61B 17/12113 within an aneurysm
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2/90 characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2002/075 the stent being loosely attached to the graft material, e.g. by stitching
• CPC Class Codes: A61F 2002/9528 for retrieval of stents

Abstract

A removable implantable medical device (1) for the endovascular treatment of aneurysm, particularly of aneurysm of the thoracic aorta, comprising a supporting structure (2) tubular in shape and covered externally by a covering (3).

The supporting structure (2) and the covering (3) define a duct (4) for blood circulation.

The device is provided with extraction means (5) for extracting the duct (4) from the body of the subject in whom it is inserted. The extraction means (5) are associated with the duct (4) and communicate with the outside of the body.

Claims

1. A method for testing insurgence of spinal ischemia due to endovascular treatment of aortic aneurisms, the method comprising:

providing an implantable and removable medical device for endovascular insertion in the thoracic aorta, said medical device comprising a supporting structure which has a substantially tubular shape and is covered externally by a covering, to define a duct for blood circulation, said device comprising extraction means for extracting said duct from a body of a patient in whom it is inserted, said extraction means being associated with said duct and communicating with an outside of said body;

introducing said device in a segment of the thoracic aorta where an aneurism is formed;

defining a duct for blood circulation with the device;

expanding the duct to make a wall of the segment radially impervious to blood, thereby reducing blood flow through the patient'"'"'s intercostal arteries;

applying a stimulus to the patient'"'"'s motor cortex;

recording muscular contractions in a patient'"'"'s peripheral region in response to the stimulus;

evaluating a patient response to reduction of blood flow through the intercostal arteries based on the recorded muscular contractions; and

selecting an aneurism treatment method based at least in part on the evaluation.

2. The method of claim 1, wherein the extraction means comprises a biocompatible cable, a first end of the cable being attached to the device and a second end of the cable protruding from the patient.

3. The method of claim 1, wherein a length of the duct defined by the device is greater than a length of the segment deformed by the aneurysm in order to avoid an inflow of blood into pockets defined between the deformed portion of blood vessel and an outer surface of the duct.

4. The method of claim 1, wherein the supporting structure comprises a meshed fabric made of biocompatible metallic material.

5. The removable implantable medical device according to claim 4, wherein the biocompatible metallic material comprises an alloy of nickel and titanium.

6. The method of claim 1, wherein the covering comprises a biocompatible polymeric material.

7. The method of claim 1, wherein the covering is sewn onto the supporting structure.

8. The method of claim 1, wherein the device assumes an active configuration, defined by a first radial dimension of the duct for defining a passage lumen for blood flow, and a compressed configuration, defined by a second radial dimension of the duct for moving the device inside a catheter for insertion, the second radial dimension being smaller than the first radial dimension.

9. The method of claim 8, wherein the extraction means activate an extraction configuration defined by a third radial dimension of the duct for avoiding damage to the intima of blood vessels during extraction, the third radial dimension being smaller than the first radial dimension.

10. The method of claim 9, wherein the third radial dimension is substantially equal to said second radial dimension.

11. The method of claim 1, further comprising:

selectively activating the extraction means in response to the recorded muscular contractions.