Sphingosine kinase type 1 inhibitors and uses thereof
First Claim
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1. A method for inhibiting the activity of sphingosine kinase 1 in a patient, comprising:
- administering to a patient a compound having the formula
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Abstract
Provided are inhibitors of sphingosine kinase Type I that are useful in a number of applications, indications and diseases, as well as for monitoring pharmacokinetics and patient management. These compounds are applicable to treating tumors of the central nervous system, such as glioblastoma multiforme (GBM).
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10 Claims
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1. A method for inhibiting the activity of sphingosine kinase 1 in a patient, comprising:
administering to a patient a compound having the formula - View Dependent Claims (2, 3)
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4. A method for inhibiting the activity of sphingosine kinase 1 in a patient, comprising:
administering to a patient a compound having the formula - View Dependent Claims (5, 6, 7, 8, 9)
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10. A method for inhibiting the activity of sphingosine kinase 1 in a patient, consisting essentially of:
administering
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