Visualization of deep brain stimulation efficacy

• US 10,625,082 B2
• Filed: 03/13/2018
• Issued: 04/21/2020
• Est. Priority Date: 03/15/2017
• Status: Active Grant

• Current Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Inventors: Laghi, Fabio
• Primary Examiner(s): Layno, Carl H
• Assistant Examiner(s): Morales, Jon Eric C
• Application Number:
  US15/920,153
• Publication Number:
  US 20180264278A1
• Time in Patent Office: 770 Days
• Field of Search: 607 45
• CPC Class Codes: A61N 1/0534 Electrodes for deep brain stimulation
• CPC Class Codes: A61N 1/36067 Movement disorders, e.g. tremor or Parkinson disease stimulating motor muscle A61N1/36003
• CPC Class Codes: A61N 1/36132 using patient feedback
• CPC Class Codes: A61N 1/36146 specified by the stimulation parameters
• CPC Class Codes: A61N 1/37223 Circuits for electromagnetic coupling
• CPC Class Codes: A61N 1/37247 User interfaces, e.g. input or presentation means

Abstract

A computing device executes a software program that communicates various deep brain stimulation (DBS) routines to a neurostimulator. The software program generates a graphical user interface (GUI) that receives inputs that are indicative of a patient'"'"'s response to the various DBS routines. The GUI further includes a representation of each of one or more electrode leads that are connected to the neurostimulator. Based on the patient response inputs, one or more symbols that are indicative of an effectiveness of the stimulation routines are displayed at positions on the lead representations that correspond to parameters of the stimulation routines.

Claims

1. A non-transitory computer-readable medium having instructions stored thereon to cause control circuitry in a computing device to:

generate a graphical user interface on a display of the computing device that includes a one or more representations of one or more electrode leads that are implantable in a patient'"'"'s brain, wherein each lead representation comprises a representation of a position of each of a plurality of electrodes and an axis for each of the plurality of electrodes representing different values of a stimulation parameter applied to the respective electrode;

cause telemetry circuitry in the computing device to communicate a stimulation routine to a neurostimulator that is connected to the one or more electrode leads and specifies one of the electrodes and a value of the stimulation parameter;

receive one or more inputs that are indicative of a patient'"'"'s response to execution of the stimulation routine by the neurostimulator; and

display on the computing device, at the position of the specified one of the electrodes and at a position along the axis for the specified one of the electrodes corresponding to the specified value of the stimulation parameter, one or more non-textual, graphical symbols that are indicative of an effectiveness of the stimulation routine, wherein the one or more non-textual, graphical symbols are based on the received one or more inputs.

2. The medium of claim 1, wherein the one or more inputs comprise one or more of a type of a symptom of the patient, an anatomical position of the patient'"'"'s symptom, or a rating of a severity of the patient'"'"'s symptom.

3. The medium of claim 1, wherein the one or more inputs comprise one or more of a type of side effect caused by the stimulation routine, an anatomical position of the side effect, or a rating of a severity of the side effect.

4. The medium of claim 1, wherein the graphical user interface comprises a field that is configured to receive a baseline rating of a severity of a symptom of the patient when no stimulation is applied.

5. The medium of claim 4, wherein the one or more non-textual, graphical symbols comprise an improvement indicator that is based on a difference between the baseline rating and a rating of a severity of the symptom when the stimulation routine is executed by the neurostimulator.

6. The medium of claim 5, wherein a color of the improvement indicator is determined based on a difference between the baseline rating and the rating of the severity of the symptom when the stimulation routine is executed by the neurostimulator.

7. The medium of claim 5, wherein the one or more non-textual, graphical symbols comprise a side effect indicator that is based on a severity of one or more side effects caused by the execution of the stimulation routine by the neurostimulator.

8. The medium of claim 7, wherein a color of the side effect indicator is determined based on the severity of the one or more side effects caused by the execution of the stimulation routine by the neurostimulator.

9. The medium of claim 8, wherein the improvement indicator is a circle and the side effect indicator is a ring around the circle.

10. The medium of claim 1, wherein each lead representation comprises one or more electrode representations.

11. The medium of claim 10, wherein the electrodes comprise a plurality of segmented electrodes and at least one of the one or more electrode representations is a segmented electrode representation that represents a set of the segmented electrodes.

12. The medium of claim 11, wherein each of the one or more electrode representations comprises an origin and one or more spokes that extend outward from the origin.

13. The medium of claim 12, wherein each spoke of the segmented electrode representation extends from the origin in a direction that corresponds to a position of one of the segmented electrodes about the electrode lead.

14. The medium of claim 1, wherein each lead representation comprises one or more electrode representations that comprise an origin and one or more spokes that extend outward from the origin.

15. The medium of claim 14, wherein the graphical user interface comprises at least one orientation adjuster to adjust an orientation of the one or more lead representations to match an orientation in which the one or more electrode leads are implanted in the patient.

16. The medium of claim 15, wherein the one or more orientation adjusters rotate the spokes of a lead representation'"'"'s electrode representations about their origin.

17. The medium of claim 14, wherein each of the spokes is a stimulation amplitude axis, and wherein the one or more non-textual, graphical symbols are displayed along the one or more spokes.

18. The medium of claim 1, wherein the one or more inputs are user inputs.

19. The medium of claim 1, wherein the one or more inputs are received from one or more sensors.

20. A system, comprising:

a neurostimulator; and

a non-transitory computer-readable medium having instructions stored thereon to cause control circuitry in a computing device to;

generate a graphical user interface on a display of the computing device that includes one or more lead representations of one or more electrode leads that are connected to the neurostimulator, wherein each lead representation comprises a representation of a position of each a plurality of electrodes and an axis for each of the plurality of electrodes representing different values of a stimulation parameter applied to the respective electrode;

cause telemetry circuitry in the computing device to communicate a stimulation routine to the neurostimulator and specifies one of the electrodes and a value of the stimulation parameter;

receive one or more inputs that are indicative of a patient'"'"'s response to execution of the stimulation routine by the neurostimulator; and

display on the computing device, at the position of the specified one of the electrodes and at a position along the axis for the specified one of the electrodes corresponding to the selected value of the stimulation parameter, one or more non-textual, graphical symbols that are indicative of an effectiveness of the stimulation routine, wherein the one or more non-textual, graphical symbols are based on the received one or more inputs.