Branched vessel endoluminal device

• US 10,631,972 B2
• Filed: 04/13/2018
• Issued: 04/28/2020
• Est. Priority Date: 01/14/2003
• Status: Active Grant

• Current Assignee: Cleveland Clinic Foundation
• Original Assignee: Cleveland Clinic Foundation
• Inventors: Greenberg, Roy K., West, Karl J., Skender, Davorin K., Foster, James C.
• Primary Examiner(s): Schall, Matthew W
• Application Number:
  US15/952,703
• Publication Number:
  US 20180243076A1
• Time in Patent Office: 746 Days
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2/856 Single tubular stent with a side portal passage
• CPC Class Codes: A61F 2/89 the wire-like elements comprising two or more adjacent rings flexibly connected by separate members
• CPC Class Codes: A61F 2002/061 provided with means for allowing access to secondary lumens
• CPC Class Codes: A61F 2002/065 Y-shaped blood vessels
• CPC Class Codes: A61F 2002/067 modular
• CPC Class Codes: A61F 2002/068 Modifying the blood flow model, e.g. by diffuser or deflector
• CPC Class Codes: A61F 2002/072 Encapsulated stents, e.g. wire or whole stent embedded in lining
• CPC Class Codes: A61F 2002/075 the stent being loosely attached to the graft material, e.g. by stitching
• CPC Class Codes: A61F 2002/828 Means for connecting a plurality of stents allowing flexibility of the whole structure
• CPC Class Codes: A61F 2230/0013 Horseshoe-shaped, e.g. crescent-shaped, C-shaped, U-shaped
• CPC Class Codes: A61F 2230/0067 conical
• CPC Class Codes: A61F 2230/0069 cylindrical
• CPC Class Codes: A61F 2250/0063 Nested prosthetic parts

Abstract

An endoluminal prosthesis comprises a prosthetic trunk having a trunk lumen and a trunk wall, a first prosthetic branch having a first branch lumen and a branch wall, and a second prosthetic branch having a second branch lumen. The first branch lumen and the second branch lumen are both in fluid communication with the trunk lumen through the trunk wall and the second branch lumen is in fluid communication with the first branch lumen through the branch wall. Additional devices, systems, and methods are disclosed.

Claims

1. A branched and fenestrated prosthesis comprising:

a tubular body of biocompatible graft material having,

a first end,

a first cylindrical portion having a first diameter,

a second end,

a second cylindrical portion having a second diameter,

a lumen between the first and second ends,

a tapered portion between the first and second cylindrical portions and tapering from the first diameter to the second diameter,

a sidewall between the first and second ends,

a branch in the side wall in the tapered portion at least partially externally of the tubular body, the branch having a first end communicating with the lumen and a second end having an opening extending toward the second end;

a fenestrated region in the second cylindrical portion comprising a first unbranched fenestration in the sidewall spaced axially from the branch and a second unbranched fenestration in the sidewall spaced axially from the branch and circumferentially offset from the first unbranched fenestration; and

a plurality of stents attached along the length of the tubular body.

2. The branched prosthesis of claim 1, wherein the first end is a proximal end and the second end is a distal end.

3. The branched and fenestrated prosthesis of claim 1, wherein at least two stents of the plurality of stents are disposed in the fenestrated region and are internal stents.

4. The branched and fenestrated prosthesis of claim 3, wherein at least two stents of the plurality of stents are disposed in the first cylindrical portion and are internal stents.

5. The branched and fenestrated prosthesis of claim 1, wherein the branch extends from the tapered portion to the second cylindrical portion.

6. The branched and fenestrated prosthesis of claim 1, further comprising a third unbranched fenestration in the second cylindrical portion.

7. The branched and fenestrated prosthesis of claim 1, wherein the first portion has a first diameter and the second portion has a second diameter less than the first diameter and the branch is in the sidewall of the first portion.

8. The branched and fenestrated prosthesis of claim 6, wherein the third unbranched fenestration is disposed more proximate the first end and the first and second unbranched fenestrations are disposed more proximate the second end.

9. The branched and fenestrated prosthesis of claim 8, wherein the first and second unbranched fenestrations are each circumferentially offset from the third unbranched fenestration.

10. The branched and fenestrated prosthesis of claim 9, wherein the branch, the first unbranched fenestration, the second unbranched fenestration, and the third unbranched fenestration are all at least partially circumferentially offset from each other.

16. The branched and fenestrated prosthesis of claim 1, wherein at least three of the stents of the plurality of stents are in the first cylindrical portion, and wherein each of the at least three stents of the plurality of stents have an amplitude and wherein one of the at least three stents has an amplitude less than the amplitude of the another of the at least three stents.

17. The branched and fenestrated prosthesis of claim 1, wherein at least three of the stents of the plurality of stents are in the second cylindrical portion, and wherein each of the at least three stents of the plurality of stents have an amplitude and wherein one of the at least three stents has an amplitude less than the amplitude of the another of the at least three stents.

19. The branched and fenestrated prosthesis of claim 17, wherein at least three of the stents of the plurality of stents are in the first cylindrical portion, and wherein each of the at least three stents of the plurality of stents have an amplitude and wherein one of the at least three stents has an amplitude less than the amplitude of the another of the at least three stents.

20. The branched and fenestrated prosthesis of claim 17, wherein at least three of the stents of the plurality of stents are in the second cylindrical portion, and wherein each of the at least three stents of the plurality of stents have an amplitude and wherein one of the at least three stents has an amplitude less than the amplitude of the another of the at least three stents.

11. A branched and fenestrated prosthesis comprising:

a tubular body of biocompatible graft material having,

a proximal inflow end,

a proximal cylindrical portion having a first diameter,

a distal outflow end,

a distal cylindrical portion distal to the first cylindrical portion and having a second diameter,

a lumen between the first and second ends,

a tapered portion between the proximal and distal cylindrical portions and tapering from the first diameter to the second diameter,

a sidewall between the proximal and distal ends,

a branch in the side wall in the tapered portion extending from the fenestration and at least partially externally of the tubular body, the branch having a first end communicating with the lumen and a second end having an opening extending toward the distal outflow end;

a fenestrated region in the distal cylindrical portion comprising a first unbranched fenestration in the sidewall spaced distally of the branch, a second unbranched fenestration in the sidewall spaced distally of the branch and circumferentially offset from the first unbranched fenestration; and

a plurality of stents attached along the length of the tubular body.

12. The branched and fenestrated prosthesis of claim 11, wherein the first diameter is greater than the second diameter.

13. The branched and fenestrated prosthesis of claim 11, wherein at least three of the stents of the plurality of stents are in the proximal cylindrical portion.

14. The branched and fenestrated prosthesis of claim 13, wherein each of the at least three stents of the plurality of stents have an amplitude and wherein one of the at least three stents has an amplitude less than the amplitude of the another of the at least three stents.

15. The branched and fenestrated prosthesis of claim 11, wherein at least three of the stents of the plurality of stents are in the distal cylindrical portion, and

wherein each of the at least three stents of the plurality of stents have an amplitude and wherein one of the at least three stents has an amplitude less than the amplitude of the another of the at least three stents.

18. A branched and fenestrated prosthesis comprising:

a tubular body of biocompatible graft material having,

a proximal inflow end,

a proximal cylindrical portion having a first diameter,

a distal outflow end,

a distal cylindrical portion distal to the first cylindrical portion and having a second diameter,

a lumen between the first and second ends,

a tapered portion between the proximal and distal cylindrical portions and tapering from the first diameter to the second diameter,

a sidewall between the proximal and distal ends,

a single branch in the side wall in the tapered portion extending from the fenestration and at least partially externally of the tubular body, the branch having a first end communicating with the lumen and a second end having an opening extending toward the distal outflow end;

a fenestrated region in the distal cylindrical portion comprising a first unbranched fenestration in the sidewall spaced distally of the branch, a second unbranched fenestration in the sidewall spaced distally of the branch and circumferentially offset from the first unbranched fenestration; and

a plurality of stents attached along the length of the tubular body.