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Method of administration and treatment

  • US 10,632,146 B2
  • Filed: 08/20/2019
  • Issued: 04/28/2020
  • Est. Priority Date: 09/15/2017
  • Status: Active Grant
First Claim
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1. The method of treating a melasma, comprising administering a transdermal formulation consisting of a buffering agent to a patient suffering from a melasma, wherein the transdermal formulation reduces the level of brown to gray-brown at the site of melasma by at least 50% wherein the buffering agent is sodium bicarbonate.

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