MRI phantom including hollow fluid filled tubular textiles for calibrated anisotropic imaging
First Claim
1. An MRI phantom for calibrated anisotropic imaging comprising:
- hollow tubular textile fibers, wherein each hollow tubular fiber has an outer diameter of less than 30 microns and an inner diameter of less than 15 microns, and wherein at least 70 percent of the hollow tubular fibers are filled with a fluid,fasciculi formed by at least some of the hollow tubular fluid filled textile fibers;
tracks formed by the combination of at least some fasciculi; and
fixed frames supporting the tracks within the phantom, wherein at least one fixed frame is formed as a fiber density frame which includes fiber density variations across the fixed frame, whereby the fibers/unit area in the fixed frame are provided at distinct known distinct test points across the fixed frame, and wherein at least one fiber density frame will vary the number of fibers at least at three distinct test points to provide the fiber density variations, and wherein at least one fiber density frame which varies the number of fibers at least at three distinct test points to provide the fiber density variations is configured to vary the number of fibers by a fixed fiber amount in adjacent test points.
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Accused Products
Abstract
A universal, modular, temperature controlled MRI phantom for calibration and validation for anisotropic and isotropic imaging comprises an outer insulating shell configured to be received within an MRI chamber; an inner shell received within the outer insulating shell; a fluid conduits adjacent the inner shell for receiving temperature controlling fluid or gas cycling there-through; and a series of stacked layers of frames containing test points for the MRI phantom, each layer including at least one fiducial and including at least some anisotropic imaging test points in at least one frame and at least one isotropic imaging test point in at least one frame. The anisotropic imaging comprises hollow tubular textile fibers, wherein each hollow tubular fiber has an outer diameter of less than 50 microns and an inner diameter of less than 20 microns, wherein at least some hollow tubular fibers are filled with a fluid.
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Citations
11 Claims
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1. An MRI phantom for calibrated anisotropic imaging comprising:
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hollow tubular textile fibers, wherein each hollow tubular fiber has an outer diameter of less than 30 microns and an inner diameter of less than 15 microns, and wherein at least 70 percent of the hollow tubular fibers are filled with a fluid, fasciculi formed by at least some of the hollow tubular fluid filled textile fibers; tracks formed by the combination of at least some fasciculi; and fixed frames supporting the tracks within the phantom, wherein at least one fixed frame is formed as a fiber density frame which includes fiber density variations across the fixed frame, whereby the fibers/unit area in the fixed frame are provided at distinct known distinct test points across the fixed frame, and wherein at least one fiber density frame will vary the number of fibers at least at three distinct test points to provide the fiber density variations, and wherein at least one fiber density frame which varies the number of fibers at least at three distinct test points to provide the fiber density variations is configured to vary the number of fibers by a fixed fiber amount in adjacent test points. - View Dependent Claims (2)
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3. An MRI phantom for calibrated anisotropic imaging comprising:
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hollow tubular textile fibers, wherein each hollow tubular fiber has an outer diameter of less than 30 microns and an inner diameter of less than 15 microns, and wherein at least 70 percent of the hollow tubular fibers are filled with a fluid, fasciculi formed by at least some of the hollow tubular fluid filled textile fibers; tracks formed by the combination of at least some fasciculi; and fixed frames supporting the tracks within the phantom, wherein at least one fixed frame is formed as a fiber crossing frame which includes test points for at least three distinct angle fiber crossings across the fiber crossing frame. - View Dependent Claims (4)
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5. An MRI phantom for calibrated anisotropic imaging comprising:
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hollow tubular textile fibers, wherein each hollow tubular fiber has an outer diameter of less than 30 microns and an inner diameter of less than 15 microns, and wherein at least 70 percent of the hollow tubular fibers are filled with a fluid, fasciculi formed by at least some of the hollow tubular fluid filled textile fibers; tracks formed by the combination of at least some fasciculi; and fixed frames supporting the tracks within the phantom, wherein at least one fixed frame is formed as a physiologic simulation frame and includes a shell simulating a human cranium, simulated eyes and tracks simulating known physiologic optical neural tracts from the simulated eyes. - View Dependent Claims (6)
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7. An MRI phantom for calibrated anisotropic imaging comprising:
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hollow tubular textile fibers, wherein each hollow tubular fiber has an outer diameter of less than 30 microns and an inner diameter of less than 15 microns, and wherein at least 70 percent of the hollow tubular fibers are filled with a fluid, fasciculi formed by at least some of the hollow tubular fluid filled textile fibers; tracks formed by the combination of at least some fasciculi; and fixed frames supporting the tracks within the phantom, wherein at least one fixed frame is formed as a routing frame which includes a plurality of distinct track starting locations at one end thereof and a plurality of aligned track ending locations at an opposed end thereof and tracks extending from the starting locations to the ending locations, wherein some of the tracks end in an ending location that is not aligned with the respective track'"'"'s starting location. - View Dependent Claims (8, 9)
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10. An MRI phantom for calibrated anisotropic imaging comprising:
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hollow tubular textile fibers, wherein each hollow tubular fiber has an outer diameter of less than 30 microns and an inner diameter of less than 15 microns, and wherein at least 70 percent of the hollow tubular fibers are filled with a fluid, fasciculi formed by at least some of the hollow tubular fluid filled textile fibers; tracks formed by the combination of at least some fasciculi; and fixed frames supporting the tracks within the phantom, wherein the phantom is configured to be worn by a patient in the MRI.
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11. An MRI phantom for calibrated anisotropic imaging comprising:
A plurality of fixed frames within the phantom, each fixed frame supporting tracks which include a plurality of hollow tubular textile fibers, wherein each hollow tubular fiber has an outer diameter of less than 25 microns and an inner diameter of less than 5 microns, and wherein at least 70 percent of the hollow tubular fibers are filled with a fluid, and wherein at least one fixed frame is formed as a fiber crossing frame which includes test points for at least three distinct angle fiber crossings across the fiber crossing frame.
Specification