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Method, system and computer readable medium for assessing actionable glycemic risk

  • US 10,638,981 B2
  • Filed: 02/16/2016
  • Issued: 05/05/2020
  • Est. Priority Date: 02/16/2015
  • Status: Active Grant
First Claim
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1. A method for assessing actionable glycemic risk comprising:

  • obtaining an output continuous glucose monitoring (BG) signal at a time t;

    determining a glycemic cost signal at the time t based on the output continuous glucose monitoring BGsignal with a glycemic cost function algorithm that attributes equal cost to each of two end points (BGtarget,lo, BGtarget,hi) of a desired blood glucose target range;

    using the glycemic cost signal to quantify actionable risk and unaddressable risk by determining an instantaneous hypoglycemia risk at the time t and an instantaneous hyperglycemia risk at the time t based on the glycemic cost signal, wherein actionable risk includes actionable hypoglycemia risk and actionable hyperglycemia risk;

    averaging each of the instantaneous hypoglycemia risk and the instantaneous hyperglycemia risk over a defined interval to determine a moving average hypoglycemia risk and a moving average hyperglycemia risk;

    averaging each of the moving average hypoglycemia risk and the moving average hyperglycemia risk across multiple days to generate a hypoglycemia risk profile (lop(s)) and a hyperglycemia risk profile (hip(s)) at time s of the day;

    administering insulin to a patient, via an insulin device, based on the generated hypoglycemia risk profile (lop(s)) and hyperglycemia risk profile (hip(s)).

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