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Method for detecting circulating cells in superficial body fluids

  • US 10,639,012 B2
  • Filed: 09/19/2016
  • Issued: 05/05/2020
  • Est. Priority Date: 09/17/2015
  • Status: Active Grant
First Claim
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1. An in vitro method for detecting and quantifying circulating cells in superficial body fluids of a subject comprisinga) placing an ultrasound-based device in contact with a liquid sample isolated from a superficial body fluid of the subject for obtaining a ultrasound data of said liquid sample;

  • b) analyzing the ultrasound data obtained in step a) by a data processing system which provides information about cells and their concentration in the fluid, andc) correlating the information obtained in step b) with the presence and amount of circulating cells in the individual,wherein the ultrasound-based device operates at a central frequency in the range of 10-100 MHz and at a pulse duration between 25-1,000 ns, and at a wavelengths between 15 and 150 μ

    m.

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