Vascular implants and methods of fabricating the same

• US 10,639,176 B2
• Filed: 11/21/2016
• Issued: 05/05/2020
• Est. Priority Date: 02/09/2007
• Status: Active Grant

• Current Assignee: Taheri Laduca LLC
• Original Assignee: Taheri Laduca LLC
• Inventors: Arnault de la Menardiere, Brice, Alavar, Frederich A. L., LaDuca, Robert C., LaDuca, Paul A., Lasalle, Carol M.
• Primary Examiner(s): Szpira, Julie A
• Application Number:
  US15/357,836
• Publication Number:
  US 20170196714A1
• Time in Patent Office: 1,261 Days
• CPC Class Codes: A61F 2/04 Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts A61F2/18, A61F2/20 take precedence; devices, other than stent-grafts, providing patency to, or preventing collapsing of, tubular structures of the body other than stent-grafts, e.g. stents A61F2/82; instruments specially adapted for placement or removal of stents or stent-grafts A61F2/95
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2/2436 Deployment by retracting a sheath
• CPC Class Codes: A61F 2/2451 Inserts in the coronary sinus for correcting the valve shape
• CPC Class Codes: A61F 2/848 having means for fixation to the vessel wall, e.g. barbs
• CPC Class Codes: A61F 2/856 Single tubular stent with a side portal passage
• CPC Class Codes: A61F 2/90 characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2002/061 provided with means for allowing access to secondary lumens
• CPC Class Codes: A61F 2002/075 the stent being loosely attached to the graft material, e.g. by stitching
• CPC Class Codes: A61F 2002/8483 Barbs
• CPC Class Codes: A61F 2210/0014 using shape memory or superelastic materials, e.g. nitinol
• CPC Class Codes: A61F 2220/0016 with sharp anchoring protrusions, e.g. barbs, pins, spikes
• CPC Class Codes: A61F 2220/0033 made by longitudinally pushing a protrusion into a complementary-shaped recess, e.g. held by friction fit
• CPC Class Codes: A61F 2220/0041 using additional screws, bolts, dowels or rivets, e.g. connecting screws
• CPC Class Codes: A61F 2220/0066 stapled
• CPC Class Codes: A61F 2220/0075 sutured, ligatured or stitched, retained or tied with a rope, string, thread, wire or cable
• CPC Class Codes: A61F 2250/0006 for adjusting angular orientation
• CPC Class Codes: A61F 2250/0007 for adjusting length
• CPC Class Codes: A61F 2250/001 for adjusting a diameter

Abstract

The present invention is directed to vascular implants and methods for fabricating the same. The implantable devices include but are not limited to stents, grafts and stent grafts. In many embodiments, the devices include one or more side branch lumens interconnected with the main lumen.

Claims

1. An implantable stent for use in a vessel or tubular structure comprising:

a unitary structure having a main lumen formed of struts and at least one side branch lumen formed of struts, wherein the main lumen has a main lumen first end and a main lumen second end, wherein the at least one side branch lumen has a side branch lumen first end and a side branch lumen second end, wherein the struts forming the side branch lumen first end are connected to the struts forming the main lumen between the main lumen first end and the main lumen second end, wherein the main lumen and the side branch lumen have a pattern of interconnected cells, wherein the size of the interconnected cells of the side branch lumen varies along a distal length of the side branch lumen, wherein an angle between the at least one side branch lumen and the main lumen is adjustable between a first angle and a second angle, wherein when the angle is the first angle, the side branch lumen second end is closer to the main lumen first end than to the main lumen second end, and wherein when the angle is the second angle, the side branch lumen second end is closer to the main lumen second end than to the main lumen first end.

2. The implantable stent of claim 1, wherein the unitary structure comprises one or more sections having cells having a first size and one or more other sections having cells having a second size different from the first size.

3. The implantable stent of claim 1, wherein the main lumen has at least one section of smaller cells adjacent at least one side branch lumen.

4. The implantable stent of claim 1, wherein the struts comprise first struts and second struts, wherein the first struts are thicker than the second struts, and wherein the first and second struts extend along a length of the main branch lumen.

5. The implantable stent of claim 1, wherein a thickness of a strut forming one of the cells at a first or second end of the main lumen is greater than a thickness of a strut forming another cell at another portion of the main lumen.

6. The implantable stent of claim 1, further comprising a graft material, wherein the graft material is adjacent at least a portion of the main lumen and at least a portion of the at least one side branch lumen, and wherein the graft material has ridges and grooves.

7. The implantable stent of claim 1, wherein the size of the interconnected cells of the side branch lumen decreases along the distal length of the side branch lumen.

8. The implantable stent of claim 1, wherein the size of the interconnected cells of the side branch lumen progressively decreases from the side branch lumen first end to the side branch lumen second end.

9. An implantable stent for use in a vessel or tubular structure comprising:

interconnected cells forming a main lumen and at least one side branch lumen, wherein the main lumen has a main lumen first end and a main lumen second end, wherein the at least one side branch lumen has a side branch lumen first end and a side branch lumen second end, wherein the side branch lumen first end is connected to the main lumen, wherein when the at least one side branch lumen is in a fully deployed configuration, the at least one side branch lumen is between the main lumen first end and the main lumen second end, wherein an angle between the at least one side branch lumen and the main lumen is adjustable between a first angle and a second angle, wherein when the angle is the first angle and the at least one side branch lumen is in the fully deployed configuration, the side branch lumen second end is closer to the main lumen first end than to the main lumen second end, wherein the stent has one or more sections having cells having a first size and one or more other sections having cells having a second size different from the first size, and wherein the size of the cells of the main branch lumen progressively decreases from a main branch lumen medial portion to at least one of the main branch lumen first end and the main branch lumen second end.

10. The implantable stent of claim 9, wherein the main lumen has at least one section of smaller cells relative to cells of at least one side branch lumen, wherein the at least one side branch lumen comprises two side branch lumens, and wherein at least a portion of the at least one section of smaller cells is between the two side branch lumens.

11. The implantable stent of claim 9, wherein when the at least one side branch lumen is in the fully deployed configuration, the cell size of the at least one side branch lumen is progressively reduced in the distal direction from the side branch lumen first end to the side branch lumen second end such that the cell size is smaller at the side branch lumen second end than at the side branch lumen first end.

12. The implantable stent of claim 9, wherein a first or second end of the main lumen has struts with a thickness greater than struts of another portion of the main lumen;

and/or

wherein the stent is configured to be attached to a sensor or a valve.

13. The implantable stent of claim 9, further comprising a graft material, wherein the graft material is adjacent at least a portion of the main lumen and at least a portion of the at least one side branch lumen, and wherein the graft material has ridges and grooves wherein when the angle is the second angle and the at least one side branch lumen is in the fully deployed configuration, the side branch lumen second end is closer to the main lumen second end than to the main lumen first end.

14. The implantable stent of claim 9, further comprising a graft material, wherein the graft material is adjacent at least a portion of the main lumen and at least a portion of the at least one side branch lumen, and wherein the graft material has ridges and grooves, wherein the ridges and grooves extend within or around at least a portion of a circumference of the main lumen and at least one of the at least one side branch lumen, and wherein the ridges and grooves extend in a longitudinal direction along at least one of the main lumen and at least one of the at least one side branch lumen.

15. An implantable stent for use in a vessel or tubular structure comprising:

interconnected struts forming a main lumen and at least one side branch lumen, wherein the main lumen has a main lumen first end and a main lumen second end, wherein the at least one side branch lumen has a side branch lumen first end and a side branch lumen second end, wherein the side branch lumen first end is attached to the main lumen, wherein when the at least one side branch lumen is in a fully deployed configuration, the side branch lumen second end is between the main lumen first end and the main lumen second end, wherein an angle between the at least one side branch lumen and the main lumen is adjustable such that the at least one side branch lumen is adjustable between a first configuration and a second configuration, wherein when the at least one side branch lumen is in the first configuration and the at least one side branch lumen is in the fully deployed configuration, the side branch lumen second end is closer to the main lumen first end than to the main lumen second end, wherein the main lumen has cells having a first size, wherein at least one side branch lumen has cells having a second size different from the first size, wherein the at least one side branch lumen has a first distal section of cells and a second distal section of cells, wherein the size of the cells of the first distal section is larger than the size of the cells of the second distal section, and wherein the second distal section is closer to the side branch lumen second end than the first distal section.

16. The implantable stent of claim 15, wherein the main lumen has at least one section of smaller cells adjacent at least one side branch lumen wherein when the at least one side branch lumen is in the second configuration and the at least one side branch lumen is in the fully deployed configuration, the side branch lumen second end is closer to the main lumen second end than to the main lumen first end.

17. The implantable stent of claim 15, wherein the main lumen has at least one section of smaller cells adjacent at least one side branch lumen, wherein the cell size of the at least one side branch lumens gets smaller in the distal direction, and wherein the stent comprises stainless steel, elgiloy, tungsten, platinum, or NITINOL.

18. The implantable stent of claim 15, further comprising a graft material, wherein the graft material is adjacent at least a portion of the main lumen and at least a portion of the at least one side branch lumen, wherein the graft material has ridges and grooves, and wherein the ridges and grooves extend within or around at least a portion of a circumference of the main lumen and at least one of the at least one side branch lumen.

19. The implantable stent of claim 15, wherein a first or second end of the main lumen has a first strut having a thickness greater than a second strut at another portion of the main lumen;

and/or

wherein the stent is configured to be attached to a sensor or a valve.

20. The implantable stent of claim 15, wherein the size of the cells of the side branch lumen progressively decreases from the side branch lumen first end to the side branch lumen second end.