Compositions

• US 10,639,253 B2
• Filed: 11/19/2015
• Issued: 05/05/2020
• Est. Priority Date: 11/21/2014
• Status: Active Grant

• Current Assignee: Symrise AG
• Original Assignee: Symrise AG
• Inventors: Pesaro, Manuel, Join, Benoit, Machinek, Arnold
• Primary Examiner(s): Roberts, Lezah
• Application Number:
  US14/946,163
• Publication Number:
  US 20160143825A1
• Time in Patent Office: 1,629 Days
• CPC Class Codes: A61K 2800/10 General cosmetic use
• CPC Class Codes: A61K 8/33 containing oxygen
• CPC Class Codes: A61K 8/34 Alcohols
• CPC Class Codes: A61K 8/347 Phenols
• CPC Class Codes: A61K 8/37 Esters of carboxylic acids
• CPC Class Codes: A61P 17/10 Anti-acne agents
• CPC Class Codes: A61P 31/04 Antibacterial agents
• CPC Class Codes: A61Q 11/00 Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
• CPC Class Codes: A61Q 13/00 Formulations or additives for perfume preparations essential oils or perfumes per se C11B9/00
• CPC Class Codes: A61Q 15/00 Anti-perspirants or body deodorants deodorisation of air A61L9/00
• CPC Class Codes: A61Q 17/005 Antimicrobial preparations
• CPC Class Codes: A61Q 17/04 Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
• CPC Class Codes: A61Q 19/00 Preparations for care of the skin
• CPC Class Codes: A61Q 19/08 Anti-ageing preparations
• CPC Class Codes: A61Q 19/10 Washing or bathing preparations
• CPC Class Codes: A61Q 5/02 Preparations for cleaning the hair
• CPC Class Codes: A61Q 5/12 Preparations containing hair conditioners
• CPC Class Codes: A61Q 9/02 Shaving preparations
• CPC Class Codes: A61Q 9/04 Depilatories

Abstract

Suggested is a composition comprising

• (a) at least one lactate ester and
• (b1) at least one second compound selected from the group encompassing benzaldehyde derivatives, aromatic aldehydes and aromatic acids.

Claims

1. A composition, consisting of

(a) at least one lactate ester selected from the group consisting of

2. The composition of claim 1, comprising

at least one species selected from group (Ia), (Ic), (Id), (Ie) and (If) and

wherein component (b) is selected from group consisting of a combination of (b1 and b2), (b2 and b3) and (b1 and b3).

3. A cosmetic or personal care composition, comprising the composition of claim 1.

4. The composition of claim 3, comprising the sum of compounds (a+b1+b2+b3) in an amount of 0.05 to 2% b.w.—

calculated on the total composition.

5. The composition of claim 3, which is a skin care composition, a hair composition, a sun care composition or a fragrance composition.

6. A method for improving antimicrobial performance of a cosmetic or personal care composition comprising incorporating a working amount of the composition of claim 1.

7. The method of claim 6, wherein an amount of 0.05 to 2% b.w. of the sum of compounds (a+b1+b2+b3) is added to a cosmetic or personal care composition.

12. The composition of claim 1, wherein the lactate ester (a) is selected from the group consisting of

13. The composition of claim 1, wherein the composition is in the absence of 3-phenyl propanol.

8. A composition comprising a mixture of compounds selected from the group consisting of

(1) butyl lactate at 1% and 3-phenylpropanol at 0.25%,

(2) butyl lactate at 1% and p-anisic acid at 0.25%,

(3) amyl lactate at 0.75% and p-anisic aldehyde at 0.25%,

(4) amyl lactate at 0.75% and 3-phenylpropanol at 0.25%,

(5) amyl lactate at 0.75% and p-anisic acid at 0.25%,

(6) benzyl lactate at 0.75% and p-anisic aldehyde at 0.25%,

(7) benzyl lactate at 0.75% and 3-phenylpropanol at 0.25%, and

(8) benzyl lactate at 0.75% and p-anisic acid at 0.25%;

and

wherein the composition has antimicrobial activity.

10. A cosmetic or personal care composition comprising the composition of claim 8.

14. The composition of claim 8, wherein:

mixture (1) is synergistic against gram negative bacterium E. coli;

mixture (2) is synergistic against mould A. brasiliensis;

mixture (3) is synergistic against gram positive bacterium S. aureus;

mixture (4) is synergistic against gram positive bacterium S. aureus;

mixture (5) is synergistic against mould A. brasiliensis;

mixture (6) is synergistic against gram positive bacterium S. aureus;

mixture (7) is synergistic against mould A. brasiliensis.

9. A composition comprising a mixture of compounds, wherein the mixture of compounds is selected from the group consisting of

(1) butyl lactate at 1% and 3-phenylpropanol at 0.25%,

(2) amyl lactate at 0.75% and p-anisic aldehyde at 0.25%,

(3) amyl lactate at 0.75% and 3-phenylpropanol at 0.25%,

(4) benzyl lactate at 0.75% and p-anisic aldehyde at 0.25%, and

(5) benzyl lactate at 0.75% and 3-phenylpropanol at 0.25%.

11. A cosmetic or personal care composition comprising the composition of claim 9.