Method for preparing 3,6-anhydro-L-galactose, and use thereof

• US 10,639,261 B2
• Filed: 08/10/2018
• Issued: 05/05/2020
• Est. Priority Date: 01/18/2012
• Status: Active Grant

• Current Assignee: Korea University Research and Business Foundation
• Original Assignee: Korea University Research and Business Foundation
• Inventors: Kim, Kyoung Heon, Choi, In Geol, Kang, Nam Joo, Yun, Eun-Ju, Lee, Sae Young, Kim, Ji Hye, Kim, Young Ah, Kim, Bo Bae, Baek, Eun Ji
• Primary Examiner(s): McIntosh, III, Traviss C
• Application Number:
  US16/100,337
• Publication Number:
  US 20180344607A1
• Time in Patent Office: 634 Days
• Field of Search: None
• CPC Class Codes: A61K 31/7004 Monosaccharides having only carbon, hydrogen and oxygen atoms
• CPC Class Codes: A61K 8/60 Sugars; Derivatives thereof
• CPC Class Codes: A61P 17/00 Drugs for dermatological disorders
• CPC Class Codes: A61P 17/16 Emollients or protectives, e.g. against radiation
• CPC Class Codes: A61P 29/00 Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
• CPC Class Codes: A61Q 19/00 Preparations for care of the skin
• CPC Class Codes: A61Q 19/007 Preparations for dry skin
• CPC Class Codes: A61Q 19/02 for chemically bleaching or whitening the skin
• CPC Class Codes: C07H 1/08 from natural products
• CPC Class Codes: C07H 3/10 Anhydrosugars, e.g. epoxides
• CPC Class Codes: C12P 19/02 Monosaccharides 2-ketogulonic acid C12P7/60
• CPC Class Codes: C12P 19/14 produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase , e.g. by cellulase, hemicellulase
• CPC Class Codes: C12Y 302/01 Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)

Abstract

The present invention relates to a method for preparing 3,6-anhydro-L-galactose, and use thereof. More specifically, 3,6-anhydro-L-galactose, which is a monosaccharide constituting agar, is produced in a high yield through chemical and enzymatic methods, and the physiological activities thereof such as whitening, moisturizing, antioxidant, antiinflammatory activities and the like are displayed, thereby enabling industrial use thereof.

Claims

1. A method for treating inflammatory diseases, comprising administering an effective amount of 3,6-anhydro-L-galactose to a subject in need thereof.

2. The method of claim 1, wherein the subject is a dog, a cat, a mouse, or a human.