Podophyllotoxin derivative with 4-position nitrogen substitution and preparation method and application thereof
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Abstract
A compound represented by formula (I) or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable formulation prepared using the compound and the salt. The compound represented by formula (I) or the pharmaceutically acceptable salt exhibits significantly higher buildup and concentration in the lungs compared to other tissues, a longer dwell time in the lungs, and/or elevated pharmaceutical efficacy.
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6 Claims
- 1. A compound of the following structure
Specification