Pharmaceutical compositions and methods for treating Alzheimer's disease
First Claim
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1. A pharmaceutical composition, comprising:
- about 12 mg to about 50 mg azelastine or a pharmaceutically acceptable salt of azelastine;
about 1 mg to about 4 mg donepezil or a pharmaceutically acceptable salt thereof, about 1 mg to about 2 mg rivastigmine or a pharmaceutically acceptable salt thereof, or about 1 mg to about 3 mg galantamine or a pharmaceutically acceptable salt thereof, or any combination thereof; and
one or more pharmaceutically acceptable excipients.
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Abstract
A pharmaceutical composition containing the therapeutically active ingredients of azelastine or a pharmaceutically acceptable salt of azelastine and donepezil or rivastigmine or galantamine or a pharmaceutically acceptable salt of thereof is disclosed. A method of using the pharmaceutical composition for treating patients suffering from mental, behavioral, cognitive disorders is also disclosed.
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Citations
15 Claims
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1. A pharmaceutical composition, comprising:
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about 12 mg to about 50 mg azelastine or a pharmaceutically acceptable salt of azelastine; about 1 mg to about 4 mg donepezil or a pharmaceutically acceptable salt thereof, about 1 mg to about 2 mg rivastigmine or a pharmaceutically acceptable salt thereof, or about 1 mg to about 3 mg galantamine or a pharmaceutically acceptable salt thereof, or any combination thereof; and one or more pharmaceutically acceptable excipients. - View Dependent Claims (2, 3, 4, 5, 6, 7)
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8. A method comprising orally administering a pharmaceutical composition to a patient having Alzheimer'"'"'s disease, the pharmaceutical composition comprising:
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about 12 mg to about 50 mg azelastine or a pharmaceutically acceptable salt of azelastine; about 1 mg to about 4 mg donepezil or a pharmaceutically acceptable salt thereof, about 1 mg to about 2 mg rivastigmine or a pharmaceutically acceptable salt thereof, or about 1 mg to about 3 mg galantamine or a pharmaceutically acceptable salt thereof, or any combination thereof; and one or more pharmaceutically acceptable excipients. - View Dependent Claims (9, 10, 11, 12, 13, 14, 15)
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Specification