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Method for treating cancer with a Coxsackievirus B3 (CVB3) variant

  • US 10,639,337 B2
  • Filed: 09/29/2017
  • Issued: 05/05/2020
  • Est. Priority Date: 09/29/2017
  • Status: Active Grant
First Claim
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1. A method for treating cancer in a subject in need thereof, comprising administering to said subject a therapeutically effective amount of a PD variant of the Coxsackie B3 group (CVB3) virus, wherein the PD variant is defined by an amino acid sequence comprising SEQ ID NO:

  • 2, and wherein the cancer is selected from the group consisting of colorectal carcinoma, esophageal cancer, breast cancer, lung cancer, pancreatic cancer, prostate cancer, gastric cancer and liver cancer.

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