Herbo-mineral formulation for prevention, treatment and management of diabetes and method of preparation thereof

• US 10,639,341 B2
• Filed: 04/23/2018
• Issued: 05/05/2020
• Est. Priority Date: 04/24/2017
• Status: Active Grant

• Current Assignee: Muniyal Ayurvedic Research Centre
• Original Assignee: Muniyal Ayurvedic Research Centre
• Inventors: Shetty, M Vijayabhanu
• Primary Examiner(s): Barker, Michael
• Assistant Examiner(s): Davis, Deborah A
• Application Number:
  US15/960,343
• Publication Number:
  US 20180236018A1
• Time in Patent Office: 743 Days
• Field of Search: 424725
• CPC Class Codes: A61K 2300/00 Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
• CPC Class Codes: A61K 33/30 Zinc; Compounds thereof
• CPC Class Codes: A61K 35/614 Cnidaria, e.g. sea anemones, corals, coral animals or jellyfish
• CPC Class Codes: A61K 36/185 Magnoliopsida (dicotyledons)
• CPC Class Codes: A61K 36/24 Apocynaceae (Dogbane family), e.g. plumeria or periwinkle
• CPC Class Codes: A61K 36/328 Commiphora, e.g. mecca myrrh or balm of Gilead
• CPC Class Codes: A61K 36/37 Celastraceae (Staff-tree or Bittersweet family), e.g. tripterygium or spindletree
• CPC Class Codes: A61K 36/59 Menispermaceae (Moonseed family), e.g. hyperbaena or coralbead
• CPC Class Codes: A61K 36/61 Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
• CPC Class Codes: A61K 36/67 Piperaceae (Pepper family), e.g. Jamaican pepper or kava
• CPC Class Codes: A61K 36/9066 Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
• CPC Class Codes: A61K 36/9068 Zingiber, e.g. garden ginger
• CPC Class Codes: A61K 45/06 Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• CPC Class Codes: A61P 3/10 for hyperglycaemia, e.g. antidiabetics

Abstract

Herbo-mineral formulation for prevention, treatment and management of Diabetes and method of preparing the same are disclosed herein. The disclosed herbo-mineral formulation includes herb and mineral elements which facilitate in treating Diabetes and Diabetes associated complications. Further the disclosed formulation has been observed to exhibit hypoglycemic, hypolipidemic, and pancreatic cell regenerative properties.

Claims

1. A process for preparation of a formulation for treatment and management of Diabetes said process comprising:

levigating at least one bhasma, Guggulu, and shilajit in a grinder to obtain a levigated mixture;

adding herbs to said levigated mixture and grinding, wherein said herbs comprise powdered form of Salacia chinensis, Withania somnifera, Boerhavia diffusa, Aristolochia indica, Aegle marmelos, Cyperus rotundus, Hemidesmus indicus, Glycyrrhiza glabra, Inula racemosa, Plumbago rosea, Terminalia chebula, Terminalia bellerica, Emblica officinalis, Piper longum, Piper nigrum, Azadirachta indica, Myrica nagi, Terminalia arjuna, Andrographis paniculata, Trichosanthes dioica, Gymnema sylvestre, Santalum alba, Woodfordia fruticosa, Mucuna pruriens, Eugenia jambolana, Curcuma longa, Zingiber officinalis and Tinospora cordifolia, and

adding grinding decoction to said grinder while continuing grinding to obtain a ground mass, wherein said grinding decoction is a decoction of ingredients comprising Salacia chinensis, Cedrus deodara, Tribulus terrestris, Acacia catechu, Andrographis paniculata, Pterocarpus marsupium, Ocimum sanctum, Adhatoda vasica, Aegle marmelos, Carum carvi, Trigonella foenum graecum, Momordica charantia and Areca catechu.

2. The process as claimed in claim 1, wherein said bhasma comprises Abhraka Bhasma, Vanga Bhasma, Yashada Bhasma, Pravala Bhasma, Loha Bhasma and Swarna Makshika Bhasma.

3. The process as claimed in claim 1, wherein said herbs comprise finely powdered form of dried root of Salacia chinensis, dried root of Withania somnifera, dried root of Boerhavia diffusa, dried root of Aristolochia indica, dried root of Aegle marmelos, dried root of Cyperus rotundus, dried root of Hemidesmus indicus, dried root of Glycyrrhiza glabra, dried root of Inula racemosa, dried root of Plumbago rosea, dried fruits of Terminalia chebula, dried fruits of Terminalia bellerica, dried fruits of Emblica officinalis, dried fruits of Piper longum, dried fruits of Piper nigrum, dried bark of Azadirachta indica, dried bark of Myrica nagi, dried bark of Terminalia arjuna, dried plant of Andrographis paniculata, dried plant of Trichosanthes dioica, dried leaves of Gymnema sylvestre, dried heartwood of Santalum alba, dried flowers of Woodfordia fruticosa, dried seeds of Mucuna pruriens, dried seeds of Eugenia jambolana, dried rhizome of Curcuma longa, dried rhizome of Zingiber officinalis and dried stem of Tinospora cordifolia.

4. The process as claimed in claim 1, wherein said grinding decoction further comprises gum acacia.

5. The process as claimed in claim 4, wherein said bhasma comprises Abhraka Bhasma, Vanga Bhasma, Yashada Bhasma, Pravala Bhasma, Loha Bhasma and Swarna Makshika Bhasma.

6. The process as claimed in claim 1, wherein preparation of said grinding decoction comprises of boiling 1 part of herbs comprising equal quantities of each of Salacia chinensis, Cedrus deodara, Tribulus terrestris, Acacia catechu, Andrographis paniculata, Pterocarpus marsupium, Ocimum sanctum, Adhatoda vasica, Aegle marmelos, Carum carvi, Trigonella foenum graecum, Momordica charantia and Areca catechu in 16 parts of water;

and reducing the liquid until ⅛

^th of the liquid remains.