System and method for an injection using a syringe needle

• US 10,639,422 B2
• Filed: 02/23/2017
• Issued: 05/05/2020
• Est. Priority Date: 07/23/2008
• Status: Active Grant

• Current Assignee: Avant Medical Corporation
• Original Assignee: Avant Medical Corporation
• Inventors: Slate, John B., Koerner, Richard J., Magers, Corey M., Burk, Michael W.
• Primary Examiner(s): Stigell, Theodore J
• Application Number:
  US15/440,420
• Publication Number:
  US 20170157326A1
• Time in Patent Office: 1,167 Days
• CPC Class Codes: A61M 2005/206 With automatic needle insertion
• CPC Class Codes: A61M 2005/208 Release is possible only when device is pushed against the skin, e.g. using a trigger which is blocked or inactive when the device is not pushed against the skin
• CPC Class Codes: A61M 2005/31588 electrically driven
• CPC Class Codes: A61M 2205/50 with microprocessors or computers
• CPC Class Codes: A61M 2205/6045 having complementary physical shapes for indexing or registration purposes
• CPC Class Codes: A61M 5/20 Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically A61M5/142 , A61M5/46 take precedence; hypodermic projectiles F42B12/54
• CPC Class Codes: A61M 5/326 Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user

Abstract

An auto-injector for injecting a fluid medicament into a patient from a pre-filled syringe requires a disposable cassette that is selectively engageable with the reusable injector. The syringe is latched onto the cassette, and the cassette is then engaged with the injector. Activation of the injector causes a first motor to move the syringe so its needle is extended from a concealed position inside the cassette for injection of the medicament. A second motor on the injector is then activated to expel fluid medicament from the syringe. Then, the first motor is again activated to withdraw the syringe into the cassette for disposal of the cassette/syringe after an injection.

Claims

1. A system for injecting a fluid medicament into a patient which comprises:

a cassette having;

a housing;

a latch mechanism; and

a hypodermic syringe, wherein the latch mechanism is operable to selectively hold the hypodermic syringe in the housing;

an injector configured to removably receive the cassette therein, the cassette having a fixation member for selectively holding the cassette in the injector;

a first motor mounted on the injector, the first motor being engageable with the cassette for moving the hypodermic syringe relative to the housing between a first position and a second position;

a second motor mounted on the injector, the second motor being engageable with the hypodermic syringe for expelling the fluid medicament from the hypodermic syringe; and

a computer mounted on the injector for coordinated control of the first and second motors.

2. A system as recited in claim 1 wherein the hypodermic syringe comprises:

a syringe chamber for holding the fluid medicament therein;

an injection needle extending from the syringe chamber; and

a plunger slidably mounted for advancement into the syringe chamber to expel fluid medicament therefrom through the injection needle.

3. A system as recited in claim 2 wherein the first position is characterized by the injection needle being withdrawn and concealed within the housing, and the second position is characterized by having the injection needle extend from the housing and from the injector for expelling the fluid medicament from the hypodermic syringe.

4. A system as recited in claim 3 wherein the latch mechanism is operable to fixedly hold the hypodermic syringe in the first position.

5. A system as recited in claim 4 wherein a duty cycle requires, in sequence:

computer control of the first motor for movement of the hypodermic syringe at a predetermined speed from the first position to the second position;

computer control of the second motor for advancement of the plunger into the syringe chamber at a predetermined rate for expelling fluid medicament from the hypodermic syringe; and

computer control of the first motor for withdrawal of the hypodermic syringe from the second position to the first position and for activation of the latch mechanism to fixedly hold the hypodermic syringe in the first position.

6. A system as recited in claim 5 wherein the predetermined speed for advancement of the hypodermic syringe from the first position to the second position is approximately 0.1 to 1 m/s.

7. A system as recited in claim 3 wherein the housing is formed with an orifice to allow for extension of the injection needle from the housing, and the system further comprises a skin sensor mounted on the injector adjacent the orifice to generate a contact signal whenever the orifice is positioned against the skin of the patient.

8. A system as recited in claim 1 wherein the cassette further comprises:

a sleeve slidingly coupled to the housing such that the sleeve is selectively movable between the first position and the second position, wherein the hypodermic syringe is fixedly held on the sleeve for movement therewith, and the latch mechanism includes a first part formed on the housing and a second part formed on the sleeve.

9. A system for injecting a fluid medicament into a patient which comprises:

a hypodermic syringe having a syringe chamber for holding the fluid medicament therein, an injection needle extending from the syringe chamber, and a plunger slidably mounted for advancement into the syringe chamber to expel fluid medicament therefrom through the injection needle;

a support means for holding the hypodermic syringe, the support means being operable such that the hypodermic syringe is selectively moveable between a first position wherein the injection needle is withdrawn and concealed and a second position wherein the injection needle extends from the support means for expelling the fluid medicament from the hypodermic syringe; and

an injector configured to removably receive the hypodermic syringe and support means therein, the injector comprising a drive means engaged with the support means and the hypodermic syringe, the drive means being bifurcated to have a first motor for moving the hypodermic syringe between the first and second positions and a second motor for advancing the plunger into the syringe chamber to expel the fluid medicament when the hypodermic syringe is in the second position.

10. A system as recited in claim 9 wherein the support means comprises a cassette including:

a housing; and

a latch mechanism comprising a portion of the housing operable to hold the hypodermic syringe in the first position.

11. A system as recited in claim 10 wherein the cassette further comprises a sleeve slidingly coupled to the housing such that the sleeve is movable between the first position and the second position, wherein the hypodermic syringe is fixedly held on the sleeve for movement therewith, and the latch mechanism comprises the portion of the housing and a portion of the sleeve.

12. A system as recited in claim 10 wherein the first motor is engageable with the housing for moving the hypodermic syringe between the first and second positions.

13. A system as recited in claim 10 further comprising a computer coupled to the drive means for coordinated control of the first motor and the second motor.

14. A system as recited in claim 13 wherein a duty cycle requires, in sequence:

computer control of the first motor for movement of the hypodermic syringe at a predetermined speed from the first position to the second position;

computer control of the second motor for advancement of the plunger into the syringe chamber with a predetermined force at a predetermined rate for expelling fluid medicament from the hypodermic syringe; and

computer control of the first motor for withdrawal of the hypodermic syringe from the first position to the second position and for activation of the latch mechanism to fixedly hold the hypodermic syringe in the first position.

15. A system as recited in claim 14 wherein the predetermined speed for advancement of the hypodermic syringe from the first position to the second position is approximately 0.1 to 1 m/s.