Systems and methods for shunting fluid

• US 10,639,461 B2
• Filed: 03/17/2017
• Issued: 05/05/2020
• Est. Priority Date: 01/22/2013
• Status: Active Grant

• Current Assignee: Anuncia Medical Incorporated
• Original Assignee: Anuncia, Inc.
• Inventors: Anand, P J, Singh, Deep Arjun, Brophy, Morgan, Fallon, Timothy, Degon, Robert, Attar, Matthew, Wong, Anthony, Waller, Allison, East, Andrew, McIntyre, Jon T.
• Primary Examiner(s): Zimbouski, Ariana
• Application Number:
  US15/462,599
• Publication Number:
  US 20170189656A1
• Time in Patent Office: 1,145 Days
• CPC Class Codes: A61M 2025/0019 Cleaning catheters or the like, e.g. for reuse of the device, for avoiding replacement
• CPC Class Codes: A61M 2039/0018 designed for flushing a line, e.g. by a by-pass
• CPC Class Codes: A61M 2205/0205 Materials having antiseptic or antimicrobial properties, e.g. silver compounds, rubber with sterilising agent
• CPC Class Codes: A61M 2205/32 with radio-opaque indicia
• CPC Class Codes: A61M 2205/3344 Measuring or controlling pressure at the body treatment site
• CPC Class Codes: A61M 2230/20 Blood composition characteristics
• CPC Class Codes: A61M 25/007 Side holes, e.g. their profiles or arrangements; Provisions to keep side holes unblocked
• CPC Class Codes: A61M 25/0071 Multiple separate lumens multiple separate lumens throughout the catheter A61M25/0026
• CPC Class Codes: A61M 25/0108 using radio-opaque or ultrasound markers
• CPC Class Codes: A61M 25/0127 Magnetic means; Magnetic markers
• CPC Class Codes: A61M 27/006 Cerebrospinal drainage; Accessories therefor, e.g. valves
• CPC Class Codes: A61M 39/225 Flush valves, i.e. bypass valves for flushing line

Abstract

Systems and methods are provided herein that generally involve shunting fluid, e.g., shunting cerebrospinal fluid in the treatment of hydrocephalus. Self-cleaning catheters are provided which include split tips configured such that pulsatile flow of fluid in a cavity in which the catheter is inserted can cause the tips to strike one another and thereby clear obstructions. Catheters with built-in flow indicators are also provided. Exemplary flow indicators include projections that extend radially inward from the interior surface of the catheter and which include imageable portions (e.g., portions which are visible under magnetic resonance imaging (MRI)). Movement of the flow indicators caused by fluid flowing through the catheter can be detected using MRI, thereby providing a reliable indication as to whether the catheter is partially or completely blocked. Systems and methods for flushing a shunt system are also disclosed herein, as are various systems and methods for opening auxiliary fluid pathways through a shunt system.

Claims

1. A flusher comprising:

an upstream port;

a downstream port;

a shunt valve disposed between the upstream and downstream ports and configured to regulate pressure in an anatomical chamber in fluid communication with the upstream port;

a ventricle channel that extends from the upstream port to a first side of a flush valve;

a flush channel that extends from a second side of the flush valve to a flush dome; and

a bypass channel that extends from the downstream port to the ventricle channel;

wherein the flush valve is configured to allow fluid communication between the first and second sides of the flush valve when a pressure differential across the flush valve exceeds a predetermined threshold; and

wherein the flush dome is collapsible to (i) force fluid through the flush valve, the ventricle channel, and the upstream port, and (ii) prevent fluid flow through the bypass channel, thereby preventing fluid from being forced through the downstream port.

2. The flusher of claim 1, further comprising a ventricular catheter in fluid communication with the upstream port.

3. The flusher of claim 2, wherein collapsing the flush dome opens an auxiliary flow path through the ventricular catheter.

4. The flusher of claim 1, wherein the flush dome is collapsible by exerting finger pressure on the flush dome through the skin of a patient in which the flush dome is implanted.

5. The flusher of claim 1, further comprising a refill valve configured to open after the flush dome is collapsed to refill the flush dome from the bypass channel.

6. The flusher of claim 5, wherein the refill valve comprises an umbrella-type check valve.

7. The flusher of claim 1, wherein the flush dome comprises a needle-pierceable septum.

8. The flusher of claim 1, wherein a pressure setting of the shunt valve is magnetically adjustable.

9. The flusher of claim 1, wherein the bypass channel extends along an exterior of the flush dome and has a length greater than a diameter of the flush dome.

10. The flusher of claim 9, wherein the bypass channel is curved in a plane parallel to a base of the flush dome.

11. A flusher, comprising:

a body with an upstream port and a downstream port;

a shunt valve that allows fluid to flow from the upstream port to the downstream port when a pressure at the upstream port exceeds an opening pressure of the shunt valve;

a flush dome; and

a flush valve disposed between the upstream port and the flush dome;

wherein an actuation force applied to the flusher is effective to;

(i) collapse the flush dome, (ii) open the flush valve to emit a pulse of fluid from the flush dome and through the upstream port, and (iii) block fluid flow between the upstream and downstream ports to prevent the pulse of fluid from flowing through the downstream port;

wherein the actuation force blocks the fluid flow between the upstream and downstream ports by occluding a bypass channel that extends along an exterior of the flush dome.

12. The flusher of claim 11, wherein the bypass channel is occluded at a midpoint of the bypass channel.

13. The flusher of claim 11, further comprising a ventricular catheter in fluid communication with the upstream port.

14. The flusher of claim 13, wherein the actuation force opens an auxiliary flow path through the ventricular catheter.

15. The flusher of claim 11, wherein the actuation force comprises finger pressure applied on the flush dome through the skin of a patient in which the flush dome is implanted.

16. The flusher of claim 11, further comprising a refill valve configured to open after the flush dome is collapsed to refill the flush dome from the bypass channel.

17. The flusher of claim 16, wherein the refill valve comprises an umbrella-type check valve.

18. The flusher of claim 11, wherein the flush dome comprises a needle-pierceable septum.

19. The flusher of claim 11, wherein the bypass channel extends along an exterior of the flush dome and has a length greater than a diameter of the flush dome.