DNA aptamers binding to molecular targeted agents and detection method of molecular targeted medicine using the same
First Claim
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1. A DNA aptamer having a nucleotide sequence of SEQ ID NO:
- 1 specifically binding to Bevacizumab.
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Abstract
The objective of the present invention is to provide a DNA aptamer that can specifically binding to a molecular targeted medicine, a composition comprising the DNA aptamer, and a method for detecting a molecular targeted medicine using the DNA aptamer.
A DNA aptamer comprising specifically binding to a molecular targeted medicine, a composition for detecting a molecular targeted medicine comprising the DNA aptamer, a kid for detecting a molecular targeted medicine, and a method for detecting a molecular targeted medicine comprising using the DNA aptamer.
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12 Claims
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1. A DNA aptamer having a nucleotide sequence of SEQ ID NO:
- 1 specifically binding to Bevacizumab.
- View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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10. A method for detecting Bevacizumab, comprising contacting the DNA aptamer having a nucleotide sequence of SEQ ID NO:
- 1 with a sample obtained from a living body selected from a group consisting of blood, blood serum, blood plasma, saliva, and sputum, and detecting the presence of the molecular targeted medicine by observing the response caused by the binding of the sample and the DNA aptamer.
- View Dependent Claims (11, 12)
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